简历：
2006.9-2010.6 四川大学化学学院化学专业，学士
2010.9-2015.6 四川大学化学学院有机化学专业，博士（导师：冯小明教授）
2015.9-2018.2 新加坡南洋理工大学，博士后（导师：Choon-Hong Tan教授）
2018.4-2021.8 四川大学化学学院 副教授
2021.9-至今 四川大学化学学院 教授
主要研究方向
不对称催化、光催化、自由基化学、有机硅化学、手性药物和生物活性化合物的合成
主要工作业绩
主要从事不对称合成研究，发展了系列不对称催化新反应、新方法和新策略，为一些具有生物活性手性化合物的合成提供了高效新途径。以第一作者或通讯作者在CCS Chem.、J. Am. Chem. Soc.、Angew. Chem.、Nat. Commun.等化学期刊发表SCI论文40余篇，其中应邀撰写综述或亮点评述7篇，多篇论文被选为封面论文、VIP论文或被Synfacts、Synlett、Org. Chem. Highlights等杂志评述，授权中国发明专利2项。主持国家自然科学基金面上项目、青年科学基金项目、四川省科技厅应用基础研究项目，作为骨干成员参与国家自然科学基金重大研究计划集成项目和区域联合基金项目。2019年获教育部自然科学奖一等奖（第五完成人），2021年入选四川省高层次人才引进计划，授予四川省特聘专家称号；2021年入选四川大学青年科技领军人才培育计划和“双百人才工程”B计划，获四川大学大学生创新创业与实践教育优秀指导教师称号；2024年获第四届全国有机自由基化学会议优秀报告奖和Wiley威立中国高贡献作者奖。
代表性成果 （获奖成果、专著、论文、专利）
1. Mingyi Jiang, Zengcheng Yu, Linhan Yang, Fei Wang, Weidi Cao,* Xiaohua Liu,* Xiaoming Feng,* Reductant-Free Enantioselective Aza-Reformatsky Reaction Enabled by Synergistic Visible Light Photocatalysis and Lewis Acid Catalysis, Angew. Chem. Int. Ed. 2025, 64, e202500756.
2. Liangkun Yang,† Lichao Ning,† Han Yu, Shiyang Li, Ming Yang, Linhan Yang, Fei Wang, Xiaohua Liu, Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Photocycloaddition of Triplet Aldehydes with Benzocyclobutenones, CCS Chem. 2025, 7, 573–581.
3. Han Yu,† Zun Yang,† Hongda Wu, Yao Luo, Weidi Cao,* Xiaohua Liu,* Xiaoming Feng,* Visible Light-Promoted Enantioselective Catalytic Alkylation of α-Ketoamides with Hydrocarbons, ChemCatChem 2025, 17, e202402112.
4. Liuzhen Hou,† Longqing Yang,† Gaofei Yang, Zhe Luo, Wanlong Xiao, Linhan Yang, Fei Wang, Liu-Zhu Gong, Xiaohua Liu,* Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Dearomative [2 + 2] Photocycloaddition/Ring-Expansion Sequence of Indoles with Diversified Alkenes, J. Am. Chem. Soc. 2024, 146, 23457–23466. (Cover Picture, highlighted by Synlett)
5. Liangkun Yang,† Shiyang Li,† Lichao Ning, Hansen Zhao, Liang Zhou, Weidi Cao,* Xiaoming Feng,* Aza-[4+2]-Cycloaddition of Benzocyclobutenones into Isoquinolinone Derivatives Enabled by Photoinduced Regio-Specific C–C Bond Cleavage, Nat. Commun. 2024, 15, 10866.
6. Yao Luo, Yuqiao Zhou, Fengnan Xiao, Xin He, Ziwei Zhong, Qi-Lin Zhou, Weidi Cao,* Xiaohua Liu,* Xiaoming Feng,* Quinone-Initiated Photocatalytic Enantioselective Giese Radical Addition with Ethers, Thioethers, Amines and Alkanes, ACS Catal. 2024, 14, 12031−12041.
7. Liuzhen Hou, Weidi Cao,* Xiaoming Feng,* Applications of Organosilanes in Visible Light-induced Catalytic Asymmetric Reactions, ChemCatChem 2024, 16, e202400385. (Invited review collected in the issue of ChineseCatChem)
8. Lili Feng, Xiaofan Chen, Ning Guo, Yuqiao Zhou, Lili Lin, Weidi Cao,* Xiaoming Feng,* Visible-Light-Induced Chemo-, Diastereo- and Enantioselective α-C(sp3)−H Functionalization of Alkyl Silanes, Chem. Sci. 2023, 14, 4516−4522.
9. Xinpeng Sang, Yuhao Mo, Shiya Li, Xiaohua Liu, Weidi Cao,* Xiaoming Feng,* Bimetallic Tandem Catalysis-Enabled Enantioselective Cycloisomerization/Carbonyl–ene Reaction for Construction of 5-Oxazoylmethyl a-Silyl Alcohol, Chem. Sci. 2023, 14, 8315−8320.
10. Ning Guo, Yao Luo, Lili Feng, Zhili Liu, Weidi Cao,* Xiaoming Feng,* Radical Conjugate Addition of Acylsilane Enabled by Synergistic Photoredox and Lewis Acid Catalysis, Asian J. Org. Chem. 2023, 12, e202300164.
11. Qianchi Lin, Siyuan Wang, Rui Weng, Weidi Cao,* Xiaoming Feng,* Chiral Lewis Acid-Catalyzed Asymmetric Multicomponent Michael Reaction through [1,2]-Phospha-Brook Rearrangement, Org. Lett. 2023, 25, 6262−6266.
12. Wanlong Xiao, Fang Li, Xiaohua Liu, Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Synthesis of Axially and Centrally Chiral 1,2-Dihydrobenzofuro[3,2-b]pyridines through a [2+2] Cycloaddition/Retroelectrocyclization/Re-Cycloaddition Cascade, Org. Lett. 2023, 25, 8005–8009.
13. Fengcai Zhang, Yuqiao Zhou, Hansen Zhao, Long Chen, Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric [3 + 2] Cycloaddition of Exocyclic Enol Ethers for the Synthesis of Spiroketals, Precis. Chem. 2023, 1, 423–428.
14. Liuzhen Hou, Xiaohua Liu, Weidi Cao,* Xiaoming Feng,* Recent Advances in Visible Light-induced Asymmetric Transformations of Carbonyl Compounds into Chiral Alcohols, ChemCatChem 2023, 15, e202300893.
15. Weidi Cao, Xiaohua Liu,* Recent Advances on Catalytic Enantioselective Protonation for Construction of α-Tertiary Carbonyl Compounds, Chin. J. Org. Chem. 2023, 43, 961–973.
16. Liuzhen Hou, Yuqiao Zhou, Han Yu, Tangyu Zhan, Weidi Cao,* Xiaoming Feng,* Enantioselective Radical Addition to Ketones through Lewis Acid-Enabled Photoredox Catalysis, J. Am. Chem. Soc. 2022, 144, 22140−22149. (Most Read Articles, highlighted by Synfacts)
17. Guihua Pan, Changli He, Min Chen, Qian Xiong, Weidi Cao,* Xiaoming Feng,* Synthesis of Dihydroisoquinoline and Dihydropyridine Derivatives via Asymmetric Dearomative Three-component Reaction, CCS Chem. 2022, 4, 2000−2008.
18. Liangkun Yang, Wang-Yuren Li, Liuzhen Hou, Tangyu Zhan, Weidi Cao,* Xiaohua Liu, Xiaoming Feng,* NickelⅡ-catalyzed Asymmetric Photoenolization/Mannich Reaction of (2-Alkylphenyl) Ketones, Chem. Sci. 2022, 13, 8576–8582.
19. Fengcai Zhang, Xinpeng Sang, Yuqiao Zhou, Weidi Cao,* Xiaoming Feng,* Enantioselective Synthesis of Azetidines through [3 + 1]-Cycloaddition of Donor−Acceptor Aziridines with Isocyanides, Org. Lett. 2022, 24, 1513−1517. (Highlighted by Org. Chem. Highlights)
20. Changqiang He, Zhikun Wu, Yuqiao Zhou, Weidi Cao,* Xiaoming Feng,* Asymmetric Catalytic Nitrooxylation and Azidation of β-Keto Amides/esters with Hypervalent Iodine Reagents, Org. Chem. Front. 2022, 9, 703−708.
21. Li Dai, Wen Liu, Yuqiao Zhou, Zi Zeng, Xinyue Hu, Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Halogenation/Semipinacol Rearrangement of 3-Hydroxyl-3-vinyl Oxindoles: A Stereodivergent Kinetic Resolution Process, Angew. Chem. Int. Ed. 2021, 60, 26599–26603.
22. Mingming Guan, Shiyu Wang, Yao Luo, Weidi Cao,* Xiaohua Liu, Xiaoming Feng,* Catalytic Asymmetric Addition of Thiols to Silyl Glyoxylates for Synthesis of Multi-hetero-atom Substituted Carbon Stereocenter, Chem. Sci. 2021, 12, 7498–7503.
23. Mingyi Jiang, Kaiqi Hu, Yuqiao Zhou, Qian Xiong, Weidi Cao,* Xiaoming Feng,* Enantioselective Isocyanide-based Multicomponent Reaction with Alkylidene Malonates and Phenols, Org. Lett. 2021, 23, 5261–5265.
24. Weidi Cao, Xiaohua Liu,* Asymmetric Formal Hetero-Ene Reaction of Allylgold Intermediates, Chin. J. Org. Chem. 2021, 41, 857−858.
25. Ziwei Zhong, Zhijie Xiao, Xiaohua Liu, Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Synthesis of 3,2'-Pyrrolinyl Spirooxindoles via Conjugate Addition/Schmidt-type Rearrangement of Vinyl Azides and (E)-Alkenyloxindoles, Chem. Sci. 2020, 11, 11492−11497.
26. Liuzhen Hou, Tengfei Kang, Liangkun Yang, Weidi Cao,* Xiaoming Feng,* Enantioselective Imino-Ene Reaction of N-Sulfonyl Ketimines with Silyl Enol Ethers: Access to Chiral Benzosultams, Org. Lett. 2020, 22, 1390−1395.
27. Yu Zhang, Hao Pan, Wen Liu, Weidi Cao,* Xiaoming Feng,*Asymmetric Catalytic Synthesis of Epoxides via Three-Component Reaction of Diazoacetates, 2‑Oxo-3-ynoates, and Nitrosoarenes, Org. Lett. 2020, 22, 6744−6749.
28. Xiangqiang Li, Mingyi Jiang, Tangyu Zhan, Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Three-component Hydroacyloxylation/1,4-Conjugate Addition of Ynamides, Chem Asian J. 2020, 15, 1953−1956.
29. Weidi Cao, Xiaohua Liu, Xiaoming Feng,* Chiral N,Nʹ-dioxide and Their Metal Complexes in Asymmetric Catalysis (in Chinese), Chin. Sci. Bull. 2020, 65, 2941−2951.
30. Bin Shen, Wen Liu, Weidi Cao,* Xiaohua Liu, Xiaoming Feng,* Asymmetric Synthesis of α,β-Epoxy-γ-lactams through Tandem Darzens/Hemiaminalization Reaction, Org. Lett. 2019, 21, 4713−4716.
31. Yan Wang, Kaixuan Wang, Weidi Cao,* Xiaohua Liu, Xiaoming Feng,* Diastereo- and Enantioselective 1,6-Conjugate Addition of 2‑Azaarylacetamides to para-Quinone Methides, Org. Lett. 2019, 21, 6063−6067.
32. Weidi Cao, Xiaoming Feng, Xiaohua Liu,* Reversal of Enantioselectivity in Chiral Metal Complex-catalyzed Asymmetric Reactions, Org. Biomol. Chem. 2019, 17, 6538−6550.
33. Wen Liu, Weidi Cao,* Haipeng Hu, Lili Lin, Xiaoming Feng,* Dynamic Kinetic Asymmetric Transformations of β-Halo-α-Keto Esters by N,N′-Dioxide/Ni(II)-Catalyzed Carbonyl-Ene Reaction, Chem. Commun. 2018, 54, 8901−8904. (Highlighted by Synfacts)
34. Hang Zhang, Qian Yao, Weidi Cao,* Shulin Ge, Jinxiu Xu, Xiaohua Liu and Xiaoming Feng,* Catalytic Enantioselective Ene-type Reactions of Vinylogous Hydrazone: Construction of α-Methylene-g-butyrolactone Derivatives, Chem. Commun. 2018, 54, 12511–12514.
35. Lifeng Wang, Weidi Cao,* Hongjiang Mei, Linfeng Hu, Xiaoming Feng,* Catalytic Asymmetric Synthesis of Chiral Spiro-Cyclopropyl Oxindoles from 3-Alkenyl-Oxindoles and Sulfoxonium Ylides, Adv. Synth. Catal. 2018, 360, 4089-4093. (VIP)
36. Changqiang He, Weidi Cao,* Jianlin Zhang, Shulin Ge, Xiaoming Feng,* Chirall N,N'-Dioxide/Scandium(III)-Catalyzed Asymmetric Alkylation of N-Unprotected 3-Substituted Oxindoles, Adv. Synth. Catal. 2018, 360, 4301-4305. (Highlighted by Synfacts)
37. Weidi Cao, Xiaohua Liu,* Xiaoming Feng, Chiral Organobases: Properties and Applications in Asymmetric Catalysis, Chin. Chem. Lett. 2018, 29, 1201−1208.
38. Weidi Cao, Davin Tan, Richmond Lee,* Choon-Hong Tan,* Enantioselective 1,2-Anionotropic Rearrangement of Acylsilane through a Bisguanidinium Silicate Ion Pair, J. Am. Chem. Soc. 2018, 140, 1952−1955.
39. Weidi Cao, Xiaohua Liu, Jing Guo, Lili Lin, Xiaoming Feng,* Asymmetric Tandem 1,5-Hydride Shift/Ring Closure for the Synthesis of Chiral Spirooxindole Tetrahydroquinolines, Chem. Eur. J. 2015, 21, 1632−1636.
40. Weidi Cao, Xiaohua Liu, Ruixue Peng, Peng He, Lili Lin, Xiaoming Feng,* Catalytic Asymmetric Cross-Dehydrogenative Coupling: Activation of C–H Bonds by a Cooperative Bimetallic Catalyst System, Chem. Commun. 2013, 49, 3470−3472.
41. Weidi Cao, Xiaohua Liu, Wentao Wang, Lili Lin, Xiaoming Feng,* Highly Enantioselective Synthesis of Tetrahydroquinolines via Cobalt(II)-Catalyzed Tandem 1,5-Hydride Transfer/Cyclization, Org. Lett. 2011, 13, 600−603. (Highlighted by Synfacts)
