简历:
学习及工作经历
2021.11-至今 四川大学化学学院,特聘研究员,博士生导师
2019.11-2021.10 德国维尔茨堡大学,博士后,合作导师:Holger Braunschweig 教授
2014.07-2019.09 新加坡南洋理工大学,博士后,合作导师:Rei Kinjo 教授
2010.09-2014.07 中国科学院大学,博士,导师:杨镜奎教授,吴海臣研究员
2007.09-2010.07 四川大学生物材料中心,硕士,导师:樊渝江教授
2003.09-2007.07 四川大学材料学院,学士
研究兴趣
我们主要关注主族元素新化合物(s区和p区元素),特别是低价态和低配位数主族元素化合物的合成、结构、成键,以及它们在小分子活化和转移,复杂化合物构建和催化反应中的机理和应用研究。研究兴趣包括:主族元素的极性反转;低价和低配位主族元素化合物的类过渡金属性质;结构新颖的主族元素卡宾、烯烃、炔烃和其它小分子类似物;弱配位离子;惰性化学键的活化等。
(课题组诚招博士后、硕(博)士研究生、研究助理以及联合培养学生,同时欢迎对元素有机化学感兴趣的本科生进入实验室参与科研项目和完成毕业设计)
主要工作业绩
硼化合物被广泛应用于合成化学(硼氢化反应、Suzuki-Miyaura反应等)、材料科学(复合材料、功能高分子材料等)和生命医学领域(分子探针、肿瘤治疗等)。有机硼化合物缺电子硼中心的极性反转,赋予了硼原子碱性和亲核性,为研究元素间新化学键的控制形成和断裂,以及新化合物的合成,提供了新的思路和方法。以此为突破口,卢伟博士在博后期间先后研究了亲核性硼锂试剂、硼-金属键化合物、硼硼双键化合物及平面碳硼烷的合成、结构和化学性质,取得了一些创新性成果和突破性研究进展。相关成果以第一作者发表于J. Am. Chem. Soc.,Angew. Chem. Int. Ed.,Nat. Commun.和Chem. Sci.等期刊。其中两篇论文分别在2019年和2020年入选“JACS青年研究者虚拟专刊”。
主要奖励和荣誉
2019年,SNIC Prof Lee Soo Ying Early Career Research Award (Gold) (新加坡)
2021年,国家级青年人才
2021年,四川大学双百B人才项目
2023年,四川省天府峨眉计划青年项目
代表性成果
加入四川大学后:
2. Qing Luo, Tingting Liu, Linlin Huang, Cheng Yang, Wei Lu*. Aromative Dephosphinidenation of a Bisphosphirane-Fused Anthracene toward E-H (E = H, Si, N and P) Bond Activation. Angew. Chem., Int. Ed. 2024, e202405122. https://doi.org/10.1002/anie.202405122.
1. Wei Lu, Nicola Hensiek, Koushik Saha, Rian D Dewhurst, Marcel Härterich, Conor Pranckevicius, Stephan Hagspiel, Maximilian Dietz, Ivo Krummenacher, Holger Braunschweig*. Electron-precise Dicationic Tetraboranes: Syntheses, Structures and Rearrangement to a Alkylidene Borate-Borenium Zwitterion and a 1, 3-Azaborinine. Chem. Eur. J. 2023, e202300644.
加入四川大学前:
1. Lu, W.; Jayaraman, A.;Fantuzzi, F.; Dewhurst, R. D.; Härterich, M.; Dietz, M.; Hagspiel, S.; Krummenacher, I.; Hammond, K.; Cui, J.; Braunschweig, H.* An Unsymmetrical, Cyclic Diborene Based on a Chelating CAAC Ligand and its Small-Molecule Activation and Rearrangement Chemistry. Angew. Chem., Int. Ed. 2021, https://doi.org/10.1002/anie.202113947. (Selected as a hot paper)
2. Lu, W.; Dinh Cao Huan Do.; Kinjo, R.* A flat carborane with multiple aromaticity beyond Wade–Mingos’ rules. Nat. Commun. 2020, 11, 3370. (Highlighted as Editor's Focus in Nature Communications); (Featured in Nature Research Chemistry Community)
3. Lu, W.; Li, Y.; Kinjo, R.* Crystalline Tetraatomic Boron(0) Species. J. Am. Chem. Soc. 2019, 141, 5164–5168. (Highlighted in chemistryviews) (selected by JACS for JACS Young Investigators Virtual Issue 2020)
4. Lu, W.; Xu, K.; Li, Y.; Hirao, H.; Kinjo, R.* Facile Activation of Homoatomic σ Bonds in White Phosphorus and Diborane by a Diboraallene. Angew. Chem., Int. Ed. 2018, 130, 15691-15695.
5. Lu, W.; Li, Y.; Ganguly, R.; Kinjo, R.* Boron Analogue of Vinylidene Dication Supported by Phosphines. J. Am. Chem. Soc. 2018, 140, 1255–1258. (selected by JACS for JACS Young Investigators Virtual Issue 2019)
6. Lu, W.; Kinjo, R.* Coordination of Asymmetric Diborenes towards Cationic Coinage Metals (Au, Ag, Cu). Chem. Eur. J. 2018, 24, 15656–15662.
7. Lu, W.; Kinjo, R.* Complexation of Asymmetric Diborenes with Magnesium Bromide. Chem. Commun. 2018, 54, 8842–8844.
8. Lu, W.; Li, Y.; Ganguly, R.; Kinjo, R.* Crystalline Neutral Allenic Diborene. Angew. Chem., Int. Ed. 2017, 56, 9829–9832. (Selected as a hot paper)
9. Lu, W.; Li, Y.; Ganguly, R.; Kinjo, R.* Alkene–Carbene Isomerization induced by Borane: Access to an Asymmetrical Diborene. J. Am. Chem. Soc. 2017, 139, 5047–5050.
10. Lu, W.; Hu, H.; Li, Y.; Ganguly, R.; Kinjo, R.* Isolation of 1,2,4,3-Triazaborol-3-yl-metal (Li, Mg, Al, Au, Zn, Sb, Bi) Derivatives and Reactivity toward CO and Isonitriles. J. Am. Chem. Soc. 2016, 138, 6650–6661.
11. Lu, W.; Gao, J.; Yang, J.;* Liu, L.; Zhao, Y.; Wu, H.* Regioselective Alkyl Transfer from Phosphonium Ylides to Functionalized Polyfluoroarenes. Chem. Sci. 2014, 5, 1934-1939.
12. Kong, L.; Lu, W.; Li, Y.; Ganguly, R.; Kinjo, R.* Formation of Boron-Main Group Element Bonds by Reactions with a Tricoordinate Organoboron L2PhB: (L = oxazol-2-ylidene). Inorg. Chem. 2017, 56, 5586-5593.
13. Kong, L.; Lu, W.; Li, Y.;Ganguly, R.; Kinjo, R.* Azaborabutadienes: Synthesis by Metal-free Carboboration of Nitriles and Utility as Building Blocks for B,N-heterocycles. Angew. Chem., Int. Ed. 2016, 55, 14718-14722.
14. Kong, L.; Lu, W.; Li, Y.;Ganguly, R.; Kinjo, R.* Isolation of a Diborane(6) Dication: Formation and Cleavage of an Electron-Precise B(sp3)-B(sp3) Bond.J. Am. Chem.Soc. 2016, 138, 8623–8629.