简历:
教育经历
2004.09~2008.06 四川大学 化学专业 理学学士学位
2008.09~2013.06 四川大学 有机化学 理学博士学位 导师:冯小明
研究及工作经历
2013.11~2016.02 德国亚琛工业大学,洪堡学者 (Carsten Bolm教授)
2016.07~2017.12 德国明斯特大学,博士后 (Gerhard Erker教授)
2018.01~2021.08 四川大学,化学学院,特聘研究员
2021.09~至今 四川大学,化学学院,教授
通讯地址:四川省成都市九眼桥望江路29号四川大学化学学院
主要研究方向
新型手性配体和催化剂的设计合成
稀土金属有机配合物催化
生物活性分子的高效合成
主要工作业绩
研究经历
董顺喜博士毕业于四川大学,师从冯小明教授,博士研究方向主要是手性胍类小分子催化剂的设计、合成及其在吖内酯参与的环化反应中的应用。2013作为洪堡学者赴德国亚琛工业大学Carsten Bolm教授课题组开展博士后研究工作,主要从事氨基酸衍生的pentathiepin设计合成以及手性氮杂环卡宾(NHC)催化不对称转化领域研究。2016年,加入德国明斯特大学Gerhard Erker课题组,开展新型受阻Lewis酸碱对(FLP)的设计合成及其反应性研究。2018年加入四川大学化学学院,主要从事(1)手性双氮氧/金属配合物催化;(2)新型手性稀土金属有机配合物催化剂设计合成及其在不对称C-H官能化、氢元素化等反应中的应用研究。截至目前,已取得一系列创新性的研究成果,在Acc. Chem. Res., Chem. Soc. Rev., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Nat. Commun., CCS Chem., ACS Catal., Sci. China Chem., Chem. Sci., J. Med. Chem.等刊物发表SCI论文40余篇,多篇工作被Synfacts杂志专题亮点评述。先后主持国家级项目和课题7项,省级重点研发项目1项。课题组发展的新型配体及其稀土金属配合物催化剂已实现商品化:https://www.jkchemical.com/news/detail/12908.
主要奖励和荣誉
2013年 获德国洪堡学者博士后奖学金
2019年 四川省引进海内外高层次人才计划
2019年 四川大学“双百人才工程” B计划
2019年 教育部高等学校科学研究优秀成果奖自然科学一等奖(排名第四)
2020年 四川大学青年科技学术带头人培育项目资助
2020年 四川大学 大学生创新创业教育优秀指导教师
2020年 四川大学 基于智慧教学环境“探究式—小班化“教学质量优秀奖
2020 年 四川大学学术新人奖
2021年 Thieme Chemistry Journals Award
2021 年 第十三批四川省学术与技术带头人后备人选
2023年 参与主讲的《手性技术》被认定为四川省首批高等学校课程思政典型案例(第四主讲人)
2024年The Distinguished Lectureship Award of The CSJ Asian International Symposium
2025年 第五届全国大学生化学实验创新设计大赛“明润-微瑞杯"西南赛区二等奖(指导教师)
2025年 原创性研究成果入选四川省第三批高等学校创新性实验项目
2025年 入选第四批“全国高校黄大年式教师团队”
学术任职
2022年~2025年 Chinese Chemical Letters 第四届青年编委会委员
2025年~2026年 Chinese Chemical Letters 第五届青年编委会委员
代表性成果(获奖成果、专著、论文、专利)
代表性论文:
1.Dong, S. X.; Feng, X. M.; Liu, X. H.* Guanidine-Amide-Based Chiral Organocatalysts and Ligands for Asymmetric Catalysis. Acc. Chem. Res. 2025, 58, DOI: 10.1021/acs.accounts.5c00662.

2.Yang, J.#; Yang, L. Q.#; Zhao, Y. X.; Hou, L. Z.; Qiu, Y.; Pan, G. H.; Liu, X. H.*; Feng, X. M.*; Dong, S. X.* Asymmetric Dearomative [2 + 2] Photocycloaddition of Quinoline and Indole Derivatives with Bicyclo[1.1.0]butanes. J. Am. Chem. Soc. 2025, 147, 35755.

3.Wang, S. Y. #; Ning L. C.#; Mao, T.; Zhou, Y. Q.; Pu, M. P.; Feng, X. M.; Dong, S. X.* Anti-Markovnikov Hydroallylation Reaction of Alkenes via Scandium-Catalyzed Allylic C‒H activation. Nat. Commun. 2025, 16, 1423.

4.Liu, Z. Z. #; Wu, H. L. #; Zhang, H. L.; Wang, F.; Liu, X. H.; Dong, S. X. *; Hong, X. *; Feng, X. M. * Iron-Catalyzed Asymmetric Imidation of Sulfides via Sterically Biased Nitrene Transfer. J. Am. Chem. Soc. 2024, 146, 18050.

5.Tan, Z.; Chen, L.; Li, L. Y.; Li, Y. Z.; Luo, Y.; Wang, F.; Dong, S. X.*; Feng, X M.* Asymmetric Synthesis of α-Methylene-γ-butyrolactones via Tandem Allylboration/Lactonization: a Kinetic Resolution Process. Angew. Chem. Int. Ed. 2023, 62, e202306146.

6.Dong, S. X.; Liu, X. H.*; Feng, X. M.* Asymmetric Catalytic Rearrangements with a-Diazocarbonyl Compounds. Acc. Chem. Res. 2022, 55, 415. (封面论文).


7.Lin, Q. C.; Zheng, S. J.; Chen, L.; Wu, J.; Li, Z. J.; Liu, P. Z.; Dong, S. X.*; Liu, X. H.; Peng, Q.*; Feng, X. M.* Catalytic Regio- and Enantioselective Protonation for the Synthesis of Chiral Allenes: Synergistic Effect of the Counterion and Water. Angew. Chem. Int. Ed. 2022, 61, e202203650 (封面论文).


8.Chen, Y. S.; Liu, Y.; Li, Z. J.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Tandem Insertion/[1,3]-Rearrangement: Highly Enantioselective Construction of α-Aminoketones. Angew. Chem. Int. Ed. 2020, 59, 8052.

9.Tang, Q.; Fu, K.; Ruan, P. R.; Dong, S. X.*; Su, Z. S; Liu, X. H.; Feng, X. M.* Asymmetric Catalytic Formal 1,4-Allylation of β,γ-Unsaturated α-Ketoesters via Allylboration/Oxy-Cope Rearrangement. Angew. Chem. Int. Ed. 2019, 58, 11846.

10.Dong, S. X.; Feng, X. M.; Liu, X. H.* Chiral Guanidine and Their Derivatives in Asymmetric Synthesis. Chem. Soc. Rev. 2018, 47, 8525.

11.Zhu, C. H.#; Zhou, Y. Q.#; Zhang, J.; Li, J. F.; Zhang, Y. X.; Wang, F.; Feng, X. M.*; Dong, S. X.* Rare-Earth Metal Catalyzed Asymmetric Addition/Hydroamidination of Nitriles and Allylamines for the Concise Synthesis of Chiral Imidazolines. CCS Chem. 2025, 7, 148.

12.Sang, X. P.; Xu, W. T.; Zhou, Y. Q.; Chen, M.; Lin, L. L.; Ji, M. H.; Wang, F.; Dong, S. X.*; Feng, X. M.* Synergistic Catalytic Synthesis of Chiral γ-Butenolides by Trapping Carboxylic Oxonium Ylides with Enones and Isatins. Sci. China Chem. 2025, 68, 5007.

13.Zhang, J.; Ning, L. C.; Qiu, Y.; Ji, M. H.; Wang, S. Y.; Wang, Y. J.; Wang, F.; Feng, X. M.; Dong, S. X.* Enantioselective Intramolecular C–H Alkylation of Pyridine Derivatives with Alkene by Rare-Earth Catalysts: Facile Synthesis of Chiral Tetrahydro-1,5-naphthyridines. Chin. Chem. Lett. 2025, DOI: 10.1016/j.cclet.2025.111442.

14.Yang, G. F.; Yang, L. Q.; Liu, Z. Z.; Song, Y. L.; Qu, Y. H.; Dong, S. X.*; Feng, X. M.* Construction of Chiral Spiro-Bridged Rings with Four Consecutive Stereocenters via Dearomative Diels–Alder Reactions of Anthracenes. Org. Lett. 2025, 27, 5112.

15.Luo, Q. L.; Zhou, Y. Q.; Zhang, J.; Dong, S. X.*; Feng, X. M*. Asymmetric Catalytic (3+2) Cyclization and Sequential Reaction to Construct Dihydrofuran- and Azepine-Based Spirooxindoles. Org. Lett. 2025, 27, 2133.

16.Li, W. Y. R.; Yang, L. Q.; Tang, X. X.; Yan, W. J.; Wu, Z.; Wang, F.; Dong, S. X.*; Feng, X. M*. Asymmetric α-Selective Allylation of Amide Unit of Maleimides and Alkenyloxindoles by Dual-functional InIII/N,N'-dioxide Complex. Org. Chem. Front. 2025, 12, 2946 (Selected as 2025 Organic Chemistry Frontiers HOT articles).

17.Zeng, Z.#; Yang, L. Q. #; Xiao, Z. J.; Chen, L.; Zhong, Z. W.; Wang, F.; Liu, X. H.; Dong, S. X.*; Feng, X. M.* A Remarkable Influence of La(III)/N,N'‑Dioxide Structure on Asymmetric Formal Substitution of 3‑Bromo-3-substituted Oxindoles with TMSCN. ACS Catal. 2024, 14, 2908.

18.Mo, Y. H.; Ning, L. C.; Luo, Z.; Yang, L. K.; Tang, S.; Dong, S. X.* Zhou, Q. L.; Feng, X. M.* Asymmetric Photoenolization/Diels-Alder Reaction of 2-Methylbenzaldehydes and 2-Alkylbenzophenones with Chromones. ACS Catal. 2024, 14, 6687.

19.Luo, Q. L.; Mao, T.; Luo, Y.; Zhang, Y. X.; Wang, F.; Dong, S. X.*; Feng, X. M*. Enantioselective Synthesis of Spiro[cyclopentane-1,3’-oxindole] Scaffolds with Five Consecutive Stereocenters. Org. Lett. 2024, 26, 6402.

20.Tan, Z.; YiHuo, A. Y.; Wu, Z. Wang, F.; Dong, S. X.*; Feng, X. M. Concise Synthesis of Chiral γ-Butenolides via an Allylation/Lactonization Cascade Reaction. Chem. Commun. 2024, 60, 7926.

21.Zhu, C. H.; Mao, T.; Feng, X. M.; Dong, S. X*. Rare-Earth-Metal-Catalyzed Regioselective Hydrosilylation of Internal Alkenes and Alkynes. Synthesis 2024, 56, 3903.

22.Li, D.; Wang, Y. J.; Wang, S. Y.; Dong, S. X.* The Effect of Basic Ligands and Alkenes on the Regioselectivity of C–H Additions of Tertiary Amines to Alkenes. Chem. Eur. J. 2024, 30, e202401014.

23.Cao, D. Y.; Xi, R. Y.; Li, H. Y.; Zhang, Z. H.; Shi, X. K.; Li, S. S.; Jin, Y. J.; Liu, W. L.; Zhang, G. L.; Liu, X. H.; Dong, S. X.*; Feng, X. M.*; Wang, F.* Discovery of a Covalent Inhibitor of Pro-Caspase-1 Zymogen Blocking NLRP3 Inflammasome Activation and Pyroptosis. J. Med. Chem. 2024, 67, 15873.

24.Dong, S. X.; Cao, W. D.; Pu, M. P.; Liu, X. H.*; Feng, X. M.* Ligand Acceleration in Chiral Lewis Acid Catalysis. CCS Chem. 2023, 5, 2717.

25.Li, D. W.; Ning, L. C.; Luo, Q. L.; Wang, S. Y.; Feng, X. M.; Dong, S. X.*. C-H alkylation of pyridines with olefins catalyzed by imidazolin-2-iminato-ligated rare-earth alkyl complexes. Sci. China Chem. 2023, 66, 1804.

26.Wang. S. Y.; Zhu, C. H.; Ning, L. C.; Li, D. W.; Feng, X. M; Dong, S. X.* Regioselective C-H alkylation of anisoles with olefins by cationic imidazolin-2-iminato scandium(III) alkyl complexes. Chem. Sci. 2023, 14. 3132 (cover picture).


27.Zhu, C. H.; Zhou, Y. Q.; Yang, J.; Feng, X. M.; Dong, S. X.* Lanthanide-catalyzed Regio- and Enantioselective Hydrosilylation of Aryl-substituted Terminal and Internal Alkenes. Org. Chem. Front. 2023, 10, 1263.

28.Wang, S. J.; Zhang, C.; F.; Li, D.; Zhou, Y. Q.; Su, Z. S.; Feng, X. M.; Dong, S. X.* New Chiral N-Heterocyclic Olefin Bifunctional Organocatalysis in α-Functionalization of β-Ketoesters. Sci. China Chem. 2023, 66, 147.

29.Wang, S. J.; Yang, J.; Zeng, H. H.; Zhou, Y. Q.; Wang, F.; Feng, X. M.; Dong, S. X.* Asymmetric Formal Coupling of β-Ketoesters with Quinones Promoted by a Chiral Bifunctional N-Heterocyclic Olefin. Org. Lett. 2023, 25, 7247.

30.Wang, Y.; Yihuo, A. Y.; Wang, L. F. Dong, S. X.*; Feng, X. M.* Catalytic Asymmetric Synthesis of Chiral Azo Compounds via Interrupted Japp–Klingemann Reaction with Aryldiazonium Salts. Sci. China Chem. 2022, 65, 546.

31.Dong, P.; Li, Z. J.; Liu, X. H.; Dong, S. X.*; Feng, X. M.* Asymmetric Synthesis of Polycyclic Spiroindolines via the Dy-catalyzed Cascade Reaction of 3-(2-Isocyanoethyl)indoles with Aziridines. Org. Chem. Front. 2022, 9, 4591.

32.Tang, X. X.; Su, Z. S.; Lin, Q. C.; Lin, L. L.; Dong, S. X.*; Feng, X. M.* Asymmetric Catalytic α-Selective Allylation of Ketones with Allyltrifluoroborates using Dual-functional Chiral InIII/N,N′-dioxide Complex. Chin. J. Chem. 2022, 40, 1793.

33.Zhong, X.; Tan, J. Q.; Qiao, J. L.; Zhou, Y. Q.; Lv, C. D.; Su, Z. S.; Dong, S. X.*; Feng, X. M.* Catalytic Asymmetric Synthesis of Spirocyclobutyl Oxindoles and Beyond via [2+2] Cycloaddition and Sequential Transformations. Chem. Sci. 2021, 12, 9991.

34.Xu, C. R.; Qiao, J. L.; Dong, S. X.*; Zhou, Y. Q.; Liu, X. H.; Feng, X. M.* Asymmetric Synthesis of Dihydro-1,3-Dioxepines by Rh(II)/Sm(III) Relay Catalytic Three-Component Tandem [4+3]-Cycloaddition. Chem. Sci. 2021, 12, 5458. This article is part of the themed collection: 2021 Chemical Science HOT Article Collection. Highlighted by Synfacts 2021, 17, 0518.

35.Xiao, W. L.; Mo, Y. H.; Guo, J.; Su, Z. S.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Catalytic Enantioselective Synthesis of Macrodiolides and their Application in Chiral Recognition. Chem. Sci., 2021, 12, 2940.

36.Xiong, Q.; Luo, Q. L.; Zhang, T. H.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Catalytic Asymmetric Multicomponent Reaction of Isocyanide, Isothiocyanate and Alkylidene Malonates. Chem. Commun. 2021, 57, 7288.

37.Tang, X. X.; Su, Z. S., Yan, L. Q.; Tang, Q.; Dong, S. X.*; Lin, L. L. Xiaoming Feng, X. M.* Diastereo- and Enantioselective Synthesis of 3-Allyl-3-hydroxyoxindoles via Allylation of Isatins. Org. Lett. 2021, 23, 8419.

38.Dong, P.; Chen, L.; Yang, Z. D.; Dong, S. X.*; Feng, X. M.* Asymmetric Cycloisomerization/[3+2] Cycloaddition for Synthesis of Chiral Spiroisobenzofuran-1,3'-pyrrolidine Derivatives. Org. Chem. Front. 2021, 8, 6874.

39.Wang, F.; Feng, L. L.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Chiral N,N′-Dioxide-Iron(III)-Catalyzed Asymmetric Sulfoxidation with Hydrogen Peroxide. Chem. Commun. 2020, 56, 3233.

40.Li, D. W.; Wang, S. J.; Ge, S. L.; Dong, S. X.*; Feng, X. M. Asymmetric Synthesis of Axially Chiral Anilides via Organocatalytic Atroposelective N-Acylation. Org. Lett. 2020, 22, 5331.

41.Dong, S. X.; Daniliuc, C. G.; Kehr, G.; Erker, G.* Formation of Active Cyclic Five-membered Frustrated Phosphane/Borane Lewis Pairs and their Cycloaddition Reactions. Chem. Eur. J. 2020, 26, 745.

42.Luo, Y.; Zhang, H.; Wang, S. Y.; Zhou, Y. Q.; Dong, S. X.*; Feng, X. M.* Asymmetric Catalytic Diverse Ring Opening/Cycloadditions of Cyclobutenones with (E)-Alkenyloxindoles and (E)-Dioxopyrrolidines. Org. Lett. 2020, 22, 2645.

43.Ge, S. L.; Zhang, Y. Y.; Tan, Z.; Li, D. W.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Bimetallic Catalytic Tandem Reaction of Acyclic Enynones: Enantioselective Access to Tetrahydrobenzofuran Derivatives. Org. Lett. 2020, 22, 3551. Highlighted by Synfacts, 2020, 16, 0820.

44.Xiong, Q. Li, G. L.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Enantioselective Synthesis of Hydrothiazole Derivatives via an Isocyanide-Based Multicomponent Reaction. Org. Lett. 2019, 21, 8771.

45.Liu, W.; Zhou, P. F.; Lang, J. W.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, A Nickel(II)-Catalyzed Asymmetric Intramolecular Alder-ene Reaction of 1,7-Dienes. Chem. Commun. 2019, 55, 4479.

46.Li, X. Q.; Xiong, Q.; Guan, M. M.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Divergent Synthesis of Enantioenriched β-Functional Amines via Desymmetrization of meso-Aziridines with Isocyanides. Org. Lett. 2019, 21, 6096.

47.Zhong, X.; Tang, Q., Zhou, P. F.; Zhong, Z. W. Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Asymmetric Synthesis of Polysubstituted Methylenecyclobutanes via Catalytic [2+2] Cycloaddition Reaction of N-Allenamides. Chem. Commun. 2018, 54, 10511. Highlighted by Synfacts 2018, 14, 1154.

书籍和教材章节:
1.Dong, S. X.; Zhao, J. N.; Feng, X. M.* Comprehensive Chirality, Second Edition, Volume 6, Chapter 1. Introduction and Remarks, Elsevier, 2023.
2.Zhao, J. N.; Dong, S. X.; Feng, X. M.* Comprehensive Chirality, Second Edition, Volume 6, Chapter 9. [4+2]-Cycloadditions (Inverse-Electron-Demand Hetero-Diels–Alder Reaction), Elsevier, 2023.
3.Wang, S. J.; Feng, X. M.; Dong, S. X.* Electronic Encyclopedia of Reagents for Organic Synthesis, 1H-Imidazole,2,3-dihydro-1,3-bis[4-methyl-2,6-bis[(1R)-1-phenylethyl] phenyl]-2-methylidene, Wiley, 2024, accepted, ID: RN02602.
4.董顺喜,第一章 烷烃,有机化学(第六版),主编:付海燕,高等教育出版社,2025.
Before SCU:
48.Dong, S. X.; Frings, M.; Cheng, H. C.; Wen, J.; Zhang, D.; Rabbe, G.; Bolm, C.* Organocatalytic Kinetic Resolution of Sulfoximines. J. Am. Chem. Soc. 2016, 138, 2166. Highlight by Synfacts 2016, 12, 634.
49.Dong, S. X.; Liu X. H.*; Zhu, Y.; He, P.; Lin, L. L.; Feng, X. M.* Organocatalytic Oxyamination of Azlactones: Kinetic Resolution of Oxaziridines and Asymmetric Synthesis of Oxazolin-4-ones. J. Am. Chem. Soc. 2013, 135, 10026. Highlight by Synfacts (2013, 1006).
50.Dong, S. X.; Liu, X. H.; Chen, X. H.; Mei, F.; Gao, B.; Lin, L. L.; Feng, X. M.* Chiral Bisguanidine-Catalyzed Inverse-Electron-Demand Hetero-Diels-Alder Reaction of Chalcones with Azlactones. J. Am. Chem. Soc. 2010, 132, 10650. Highlight by Synfacts (2010, 1105).
51.Dong, S. X.; Frings, M.; Zhang, D.; Guo. Q. Q.; Danilliuc, C. G.; Cheng, H. C.; Bolm, C.* Organocatalytic Asymmetric Synthesis of trans-γ-Lactams. Chem. Eur. J. 2017, 23, 13888.
52.Dong, S. X.; Wang, L.; Wang, T.; Daniliuc, C. G.; Brinkkötter, M.; Eckert, H.; Kehra. G.; Erker, G. Formation and Reactions of Active Five-membered Phosphane/borane Frustrated Lewis Pair Ring Systems. Dalton Trans. 2018, 47, 4449.
53.Dong, S. X.; Liu, X. H*.; Zhang, Y. L.; Lin, L. L.; Feng, X. M *. Asymmetric Synthesis of 3,4-Diaminochroman-2-ones Promoted by Guanidine and Bisguanidium Salt. Org. Lett. 2011, 13, 5060.
54.Liu, X. H.; Dong, S. X.; Lin, L. L.; Feng, X. M.* Chiral Amino Acids-Derived Catalysts and Ligands. Chin. J. Chem, 2018, 36, 791.
55.Guo, J.; Dong, S. X.; Zhang, Y. L.; Kuang, Y. L.; Feng, X. M.* Chiral Scandium(III)-Catalyzed Enantioselective α-Arylation of N-Unprotected 3-Substituted Oxindoles with Diaryliodonium Salts. Angew. Chem., Int. Ed. 2013, 52, 10245. Highlight by Synfacts (2013, 1262).
56.Wang, L.; Dong, S. X.; Daniliuc, C. G.; Liu, L.; Grimme, S.; Knitsch, R.; Eckert, H.; Hansen, M. R.; Kehra. G.; Erker, G. Formation of Macrocyclic Ring Systems by Carbonylation of Trifunctional P/B/B Frustrated Lewis Pairs. Chem. Sci. 2018, 9, 1544.