四川大学化学学院
师资力量

于珊珊     副教授

研究方向:手性荧光探针

联系方式:028-85418580          Email:yushanshan@scu.edu.cn

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教育及工作经历

2013.11–至今    四川大学化学学院,副教授

2008.8 – 2013.8  美国弗吉尼亚大学化学系,有机化学,博士,导师:Lin Pu

2004.9 – 2008.6  武汉大学化学与分子科学学院,学士

荣誉和奖励

四川省科技进步(自然科学类)二等奖,2019,基于联萘酚结构的荧光探针。完成人:余孝其、于珊珊、李坤

代表性论文

1.  Tian, J.; Wang, Y.; Chen, Y.; Zhao, F.; Jiang, Y.; Yu, S.; Yu, X.; Pu, L., Chemoselective and enantioselective fluorescent recognition of glutamic and aspartic acids. Chem. Commun. 2020, 56 (95), 15012-15015.

2.  Zhao, F.; Wang, Y.; Wu, X.; Yu, S.; Yu, X.; Pu, L., Sulfonation of 3,3 '-Diformyl-BINOL for Enantioselective Fluorescent Recognition of Amino Acids in Water. Chem. Eur. J. 2020, 26 (32), 7258-7262.

3.  Zhao, F.; Tian, J.; Wu, X.; Li, S.; Chen, Y.; Yu, S.; Yu, X.; Pu, L., A near-IR Fluorescent Probe for Enantioselective Recognition of Amino Acids in Aqueous Solution. J. Org. Chem. 2020, 85 (11), 7342-7348.

4.  Wang, X.; Jiang, Y.; Chen, Y.; Yu, S.; Shi, D.; Zhao, F.; Chen, Y.; Wang, Y.; Huo, B.; Yu, X.; Pu, L., Opposite Enantioselectivity of Mg(II) Versus Zn(II) in the Fluorescent Recognition of Amino Acids. J. Org. Chem. 2020, 85 (7), 4901-4905.

5.  Iqbal, S.; Yu, S.; Jiang, L.; Wang, X.; Chen, Y.; Wang, Y.; Yu, X.; Pu, L., Simultaneous Determination of Concentration and Enantiomeric Composition of Amino Acids in Aqueous Solution by Using a Tetrabromobinaphthyl Dialdehyde Probe. Chem. Eur. J. 2019, 25 (42), 9967-9972.

6.  Jiang, L.; Tian, J.; Zhao, F.; Yu, S.; Shi, D.; Wang, X.; Yu, X.; Pu, L., Fluorescent Recognition of Functional Secondary Amines in the Fluorous Phase. Eur. J. Org. Chem. 2019, 2019 (14), 2533-2538.

7.  Zhao, F.; Du, Y.; Tian, J.; Shi, D.; Wang, Y.; Hu, L.; Yu, S.; Yu, X.; Pu, L., Enantioselective Fluorescent Recognition of Amino Acids in Aqueous Solution by Using a Chiral Aldehyde Probe. Eur. J. Org. Chem. 2018, (16), 1891-1895.

8.  Hu, L.; Wang, Y.; Duan, P.; Du, Y.; Tian, J.; Shi, D.; Wang, X.; Yu, S.; Yu, X.; Pu, L., Fluorescent Discrimination of Primary Alkyl Amines by Using a Binaphthyl Ladder Polymer. Eur. J. Org. Chem. 2018, (16), 1896-1901.

9.  Iqbal, S.; Yu, S.; Zhao, F.; Wang, Y.; Tian, J.; Jiang, L.; Du, Y.; Yu, X.; Pu, L., Discriminating three biothiols by using one fluorescent probe. Tetrahedron Lett. 2018, 59 (37), 3397-3400.

10.  Shi, D.; Wang, X.; Yu, S.; Zhao, F.; Wang, Y.; Tian, J.; Hu, L.; Yu, X.; Pu, L., Fluorescent Recognition of 1,3-Diaminopropane in the Fluorous Phase - Greatly Enhanced Sensitivity and Selectivity. Eur. J. Org. Chem. 2018, (8), 1053-1059.

11.  Wang, P.; Wang, L.; Yu, S.; Wang, Q.; Pu, L., O-Alkylation of 3-Formyl-BINOL and Its Strong Effect on the Fluorescence Recognition of 1,3-Diaminopropane. Eur. J. Org. Chem. 2018, (36), 4972-4977.

12.  Wang, X.; Shi, D.; Xu, Y.; Yu, S.; Zhao, F.; Wang, Y.; Hu, L.; Tian, J.; Yu, X.; Pu, L., Reaction of Zn(II) with a BINOL-amino-acid Schiff base: An unusual off-on-off fluorescence response. Tetrahedron Lett. 2018, 59 (24), 2332-2334.

13.  Yu, S.; Pu, L., 8.07 - Fluorescent Sensing of Chirality A2 - Atwood, Jerry L. In Comprehensive Supramolecular Chemistry II, Elsevier: Oxford, 2017; pp 129-160.

14.  Hu, L.; Yu, S.; Wang, Y.; Yu, X.; Pu, L., Enhanced Fluorescence of 3,3 '-Diformyl BINOL by Functional Secondary Amines. Org. Lett. 2017, 19 (14), 3779-3782.

15.  Chen, L.; Yu, S.; Xiao, M.; Huang, Z.; Wen, K.; Xu, Y.; Zhao, F.; Yu, X.; Pu, L., Recognition of Chiral Amines by a Terpyridine-Zn-II-Complex-Based Circular-Dichroism Sensor. Eur. J. Org. Chem. 2017, (16), 2338-2343.

16.  Wang, Y.; Hu, L.; Zhao, F.; Yu, S.; Tian, J.; Shi, D.; Wang, X.; Yu, X.; Pu, L., Polymer Amplified Enantioselectivity in the Fluorescent Recognition of Prolinol. Chem. Eur. J. 2017, 23 (70), 17678-17681.

17.  Xiao, M.; Yu, S.; Chen, L.; Huang, Z.; Wen, K.; Xu, Y.; Zhao, F.; Yu, X.; Pu, L., Fluorous-Phase-Based Chiral Assay with Circular Dichroism Spectroscopy. Eur. J. Org. Chem. 2017, (11), 1413-1417.

18.  Xu, Y.; Shi, D.; Wang, X.; Yu, S.; Yu, X.; Pu, L., Development of Aldehyde-Based Fluorescent Probes for Highly Selective Recognition of 1,3-Diaminopropane. Eur. J. Org. Chem. 2017, 2017 (33), 4990-4994.

19.  Du, J.; Yu, S.; Huang, Z.; Chen, L.; Xu, Y.; Zhang, G.; Chen, Q.; Yu, X.; Pu, L., Highly selective ratiometric fluorescent recognition of histidine by tetraphenylethene-terpyridine-Zn(ii) complexes. RSC Adv. 2016, 6 (30), 25319-25329.

20.  Xu, Y.; Yu, S.; Chen, Q.; Chen, X.; Li, Y.; Yu, X.; Pu, L., Fluorescent Recognition of 1,2-Diamines by a 1,1′-Binaphthyl-Based Trifluoromethyl Ketone. Chem. Eur. J. 2016, 22 (34), 12061-12067.

21.  Xu, Y.; Yu, S.; Chen, Q.; Chen, X.; Xiao, M.; Chen, L.; Yu, X.; Xu, Y.; Pu, L., Greatly Enhanced Fluorescence by Increasing the Structural Rigidity of an Imine: Enantioselective Recognition of 1,2-Cyclohexanediamine by a Chiral Aldehyde. Chem. Eur. J. 2016, 22 (17), 5963-5968.

22.  Xu, Y.; Yu, S.; Wang, Y.; Hu, L.; Zhao, F.; Chen, X.; Li, Y.; Yu, X.; Pu, L., Ratiometric Fluorescence Sensors for 1,2-Diamines Based on Trifluoromethyl Ketones. Eur. J. Org. Chem. 2016, 2016 (35), 5868-5875.

23.  Wen, K.; Yu, S.; Huang, Z.; Chen, L.; Xiao, M.; Yu, X.; Pu, L., Rational design of a fluorescent sensor to simultaneously determine both the enantiomeric composition and the concentration of chiral functional amines. J. Am. Chem. Soc. 2015, 137 (13), 4517-24.

24.  Yu, S.; Pu, L., Recent progress on using BINOLs in enantioselective molecular recognition. Tetrahedron 2015, 71 (5), 745-772.

25.  Zhou, X.; Huang, Z.; Cao, Y.; Yu, S.; Yu, X.; Zhao, G.; Pu, L., Spectroscopic studies on the interaction of terpyridine-CuCl2 with cysteine. RSC Adv. 2015, 5 (66), 53905-53910.

26.  Huang, Z.; Yu, S.; Wen, K.; Yu, X.; Pu, L., Zn(II) promoted dramatic enhancement in the enantioselective fluorescent recognition of functional chiral amines by a chiral aldehyde. Chem. Sci. 2014, 5 (9), 3457-3462.

27.  Huang, Z.; Yu, S.; Zhao, X.; Wen, K.; Xu, Y.; Yu, X.; Xu, Y.; Pu, L., A Convenient Fluorescent Method to Simultaneously Determine the Enantiomeric Composition and Concentration of Functional Chiral Amines. Chem. Eur. J. 2014, 20 (50), 16458-16461.

28.  Yu, S.; Plunkett, W.; Kim, M.; Wu, E.; Pu, L., 1,1'-Bi-2-naphthol-fluoroacetyl compounds in fluorescent recognition of amines. Org. Chem. Front. 2014, 1 (4), 395-404.

29.  Yu, S.; Pu, L., Chiral Recognition by Fluorescence: One Measurement for Two Parameters. Advances in Chemistry 2014, 2014, 14.

30.  Yu, S. S.; Pu, L., One enantiomeric fluorescent sensor pair to discriminate four stereoisomers of threonines. Science China-Chemistry 2013, 56 (3), 301-306.

31.  Yu, S. S.; Plunkett, W.; Kim, M.; Wu, E.; Sabat, M.; Pu, L., Molecular Recognition of Aliphatic Diamines by 3,3 '-Di(trifluoroacetyl)-1,1 '-bi-2-naphthol. J. Org. Chem. 2013, 78 (24), 12671-12680.

32.  Yu, S. S.; Plunkett, W.; Kim, M.; Pu, L., Simultaneous Determination of Both the Enantiomeric Composition and Concentration of a Chiral Substrate with One Fluorescent Sensor. J. Am. Chem. Soc. 2012, 134 (50), 20282-20285.

33.  Yu, S. S.; DeBerardinis, A. M.; Turlington, M.; Pu, L., Study of the Fluorescent Properties of Partially Hydrogenated 1, 1 '-Bi-2-naphthol-amine Molecules and Their Use for Enantioselective Fluorescent Recognition. J. Org. Chem. 2011, 76 (8), 2814-2819.

34.  Yu, S. S.; Pu, L., Pseudoenantiomeric Fluorescent Sensors in a Chiral Assay. J. Am. Chem. Soc. 2010, 132 (50), 17698-17700.

 

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