四川大学化学学院
师资力量

吴 鹏     教授、博士生导师

研究方向:光谱分析;纳米生物分析;环境分析与检测

联系方式:028-85415145          Email:wupeng@scu.edu.cn; wupeng522@gmail.com

个人主页:点击进入

简历

1999.9-2003.6,四川大学化学学院应用化学专业,理学学士

2003.9-2006.6,四川大学化学学院分析化学专业,理学硕士

2006.7-2008.6,四川大学分析测试中心,助教/助理研究员

2008.9-2011.6,南开大学化学学院分析化学专业,理学博士

2011.6-2016.9,四川大学分析测试中心,副研究员

2013.7-2016.11,南京大学化学化工学院,博士后

2016.10-至今,四川大学分析测试中心/化学学院,研究员

主要研究方向

1.    光谱分析

2.    纳米生物分析

3.    环境分析与监测

主要工作业绩

主要工作业绩:

  研究兴趣为单线态氧和室温磷光。近年来的研究工作以室温磷光的光物理和光化学调控为基础,探究其在分析化学、环境化学以及生物医学领域的新应用。创建了若干污染物和生物分子的高灵敏和高选择性分析新方法,为复杂样品的高灵敏和高选择性分析提供了新策略和新途径。已在Angew. Chem.Nat CommunNano Lett.Anal. Chem.等杂志上发表第一/通讯作者SCI论文70余篇,H-index34


主持科研项目:

1.  国家自然科学基金面上项目,基于DNA基质流体室温磷光原理的显色分析,2019-2022

2.  四川省杰出青年基金,基于掺杂量子点的光学传感,2016-2019

3.  国家自然科学基金优秀青年基金,分析化学,2016-2018

4.  国家自然科学基金面上项目,蛋白质介导合成低毒性掺杂量子点及其在光学传感中的应用,2015-2018


主要学术兼职和荣誉:

1.  国家优秀青年基金获得者(2015

2.  四川省杰出青年基金获得者(2015

3.  《中国测试》编委(2012-

代表性成果

(获奖成果、专著、论文、专利)

近年发表的部分论文(全部论文,请点击个人主页):

2021年:

1.         Wang, Y.; Li, J. Z.; Zhou, Z. W.; Zhou, R. H.; Sun, Q.; Wu,   Peng* Halo-Fluorescein for Photodynamic Bacteria Inactivation in   Extremely Acidic Conditions. Nat. Commun. 2021, 12, 526.

 

2.         Li, Y. J.; Zhou, R. H.; Xiao, D. X.; Shi, S. R.; Peng, S. L.;   Wu, S. H.; Wu, Peng*; Lin, Y. F.* Polypeptide uploaded   efficient nanophotosensitizers to overcome photodynamic resistance for   enhanced anticancer therapy. Chem. Eng. J. 2021, 403, 126344.

 

 

2020年:

3.         Wang, Y. Y.; Hu, H.; Dong, T. Y.; Mansour, H.; Zhang, X. F.; Li,   F.*; Wu, Peng* Double Stranded DNA Matrix for   Photosensitization Switching. CCS Chem. 2020, 2, 2394-2404.

 

4.         Zhang, X.; Yang, Q.; Lang, Y. H.; Jiang, X.; Wu, Peng*   Rationale of 3,3’,5,5’-Tetramethylbenzidine (TMB) as the Chromogenic   Substrate in Colorimetric Analysis. Anal. Chem. 2020, 92,   12400-12406.

 

5.         Dong, T. Y.; Mansour, H.; Hu, H.; Wang, G. A.; Watson, C. J. F.;   Yousef, M.; Matamoros, G.; Sanchez, A. L.; MacNeil, A. J.; Wu, Peng*;   Li, F.* Colorimetric Polymerase Chain Reaction Enabled by a Fast   Light-Activated Substrate Chromogenic Detection Platform. Anal. Chem.   2020, 92, 6456-6461.

 

6.         Zhang, X. F.; Fan, X. Y.; Wang, Y. Y.; Lei, F. J.; Li, L.; Liu,   J. W.*; Wu, Peng* Highly Stable Colorimetric Sensing by   Assembly of Gold Nanoparticles with SYBR Green Ifrom   Charge Screening to Charge Neutralization. Anal. Chem. 2020,   92, 1455-1462.

 

7.         Zhang, J. Y.; Wu, S. H.; Ma, L. Z.; Wu, Peng*;   Liu, J. W.* Graphene oxide as a photocatalytic nuclease mimicking nanozyme   for DNA cleavage. Nano Res. 2020, 13, 455-460.

 

8.         Wu, S. H.; Zhou, R. H.; Chen, H. J.; Zhang, J. Y.; Wu,   Peng* Highly Efficient Oxygen Photosensitization of Carbon dots: the   Role of Nitrogen Doping. Nanoscale 2020, 12, 5543-5553.

 

9.         Wang, Y. Y.; Zhou, R. H.; Liu, W. X.; Liu, C.*; Wu, Peng*   Comparison of Benzothiazole-based Dyes for Sensitive DNA Detection. Chin.   Chem. Lett. 2020, 31, 2950-2954.

10.     Li, X. M.; Zheng, T.; Gao, L.; Li, F.*; Hou, X. D.; Wu,   Peng*  Recombinase Polymerase Amplification: from Principle to   Performance. Chem. J. Chin. Univ.-Chin. 2020, 41, 2587-2597.

11.     Zheng, H.; Zhang, X.; Chen, D.; Wu, Peng* Easily   Ignored Interference Light from the Second Order Diffraction of the   Excitation Grating in a Xenon Lamp-based Spectrometer. Results Chem.   2020, 2, 100072.

 

2019年:

12.     Zhang, J. Y.; Wu, S. H.; Lu, X. M.; Wu, Peng*;   Liu, J. W.* Lanthanide Boosted Singlet Oxygen from Diverse Photosensitizers   along with Potent Photocatalytic Oxidation. ACS Nano 2019, 13,   14152-14161.

 

13.     Zhang, J. Y.; Wu, S. H.; Lu, X. M.; Wu, Peng*;   Liu, J. W.* Manganese as a Catalytic Mediator for Photo-oxidation and   Breaking the pH Limitation of Nanozymes. Nano Lett. 2019,   19, 3214-3220.

 

14.     Fan, X. Y.; Wang, Y. Y.; Deng, L.; Li, L.; Zhang, X. F.*; Wu,   Peng* Oxidative Capacity Storage of Transient Singlet Oxygen from   Photosensitization with a Redox Mediator for Improved Chemiluminescent   Sensing. Anal. Chem., 2019, 91, 9407-9412.

 

15.     Xiong, J.; Xu, K. L.*; Hou, X. D.; Wu, Peng*   AuNCs-Catalyzed Hydrogen Selenide Oxidation: Mechanism and Application for   Headspace Fluorescent Detection of Se(IV). Anal. Chem. 2019,   91, 6141-6148.

 

16.     Li, X. M.; Gao, L.; Li, F.; Hou, X. D.; Wu, Peng*   Universal and Label-Free Photosensitization Colorimetric Assays Enabled by   Target-Induced Termini Transformation of dsDNA Resistant to Exo III   Digestion. Chem. Commun. 2019, 55, 7211-7214.

 

17.     Liu, J.; Wu, S. H.; Chu, H. Y.; Wang, C. Z.; Shen, J. W.*; Wei,   Y. M.; Wu, Peng* Low power density 980 nm driven ultrabright   red-emitting upconversion nanoparticles via synergetic Yb3+/Tm3+   cascade-sensitization. J. Mater. Chem. C, 2019, 2019, 7,   13415-13424.

 

18.     Li, C. B.; Wang, Y.; Li, C. H.; Xu, S. X.*; Hou, X. D.; Wu,   Peng* Simultaneously Broadened Visible Light Absorption and Boosted   Intersystem Crossing in Platinum-Doped Graphite Carbon Nitride for Enhanced   Photosensitization. ACS Appl. Mater. Interfaces 2019,   11, 20770-20777.

 

19.     Wang, Y.; Chen, H. J.; Li, C. H.; Wu, Peng*   Octachloro-fluorescein: Synthesis and photosensitizer performance evaluation.   Dyes Pigment., 2019, 170, 107635.

 

20.     Zhang, J. Y.; Zhou, R. H.; Tang, D. D.; Hou, X. D.*; Wu,   Peng* Optically-active nanocrystals for inner filter effect-based   fluorescence sensing: Achieving better spectral overlap. Trends Anal.   Chem., 2019, 110, 183-190.

Figure 1

 

21.     Ding, Y.; Li, X. M.; Zhang, X. F.; Li, F.*; Hou, X. D.; Wu,   Peng* Systematic Probing the Sequence Selectivity of Exonuclease III   with a Photosensitization Colorimetric Assay. ACS Omega, 2019,   4, 13382-13387.

22.     Wang, Y. Y.; Dong, Z.; Hu, H.; Yang, Q.*; Hou, X. D.; Wu,   Peng* DNA-Modulated Photosensitization: Current Status and Future   Aspects in Biosensing and Environmental Monitoring. Anal. Bioanal.   Chem., 2019, 411, 4415-4423. (Invited Contribution)

23.     Zhou, R. H.; Lu, X. M.; Yang, Q.*; Wu, Peng*   Nanocrystals for large Stokes shift-based optosensing. Chin. Chem.   Lett., 2019, 30, 1843-1848.

24.     Wu, S. H.; Zhang, J. Y.; Wu, Peng* Photo-Modulated   Nanozyme for Biosensing and Biomedical Applications. Anal. Methods,   2019, 11, 5081-5088.

25.     Li, C. H.; Wu, Peng* Cu‐Doped Quantum Dots: a New   Class of Near-Infrared Emitting Fluorophores for Bioanalysis and Bioimaging. Luminescence,   2019, 34, 782-789.

 

2018年:

1.         Zhang, J. Y.; Lu, X. M.; Tang, D. D.; Wu, S. H.; Hou, X. D.;   Liu, J. W.*; Wu, Peng* Phosphorescent Carbon Dots for Highly   Efficient Oxygen Photosensitization and as Photooxidative Nanozymes. ACS   Appl. Mater. Interfaces, 2018, 10, 40808-40814.

 

2.         Zhang, X. F.; Deng, L.; Huang, C. P.; Zhang, J. Y.; Hou, X. D.; Wu,   Peng*; Liu, J. W.* Photosensitization of Molecular Oxygen on Graphene   Oxide for Ultrasensitive Signal Amplification. Chem. Eur. J., 2018,   24, 2602-2608.

TOC

 

3.         Huang, C. P.; Fan, X. Y.; Yuan, Q. M.; Zhang, X. F.*; Hou, X.   D.; Wu, Peng* Colorimetric determination of uranyl (UO2+2) in   seawater via DNAzyme-modulated photosensitization. Talanta, 2018,   185, 258-263.

Scheme 1

 

4.         Deng, L.; Wu, Y. H.; Xu, S. X.; Tang, Y. R.; Zhang, X. F.*; Wu,   Peng* Improving the Signal-to-Background Ratio during Catalytic   Hairpin Assembly through Both-End Blocked DNAzyme. ACS Sens.,   2018, 3, 1190-1195.

Graph1 - Copy

 

5.         Lu, X. M.; Zhang, J. Y.; Xie, Y.-N.; Zhang, X. F.; Jiang, X.   M.*; Hou, X. D.; Wu, Peng* Ratiometric Phosphorescent Probe for   Thallium in Serum, Water, and Soil Samples Based on Long-Lived,   Spectrally-Resolved Mn-doped ZnSe Quantum Dots and Carbon Dots. Anal.   Chem., 2018, 90, 2939-2945.

TOC

 

6.         Zhou, R. H.; Sun, S.-K.; Li, C. H.; Wu, L.; Hou, X. D.*; Wu,   Peng* Enriching Mn-Doped ZnSe Quantum Dots onto Mesoporous Silica   Nanoparticles for Enhanced Fluorescence/Magnetic Resonance Imaging Dual-Modal   Bio-Imaging. ACS Appl. Mater. Interfaces, 2018, 10,   34060-34067.

Scheme 1

 

7.         Zhang, J. Y.; Tang, D. D.; Yao, Y. D.; Hou, X. D.*; Wu,   Peng* Aggregation-Induced Phosphorescence Enhancement of Mn-Doped ZnS   Quantum Dots: the Role of Dot-to-Dot Distance. Nanoscale, 2018,   10, 9236-9244.

 

8.         Tang, D. D.; Zhang, J. Y.; Zhou, R. X.; Xie, Y.-N.; Hou, X. D.;   Xu, K. L.*; Wu, Peng* Phosphorescent Inner Filter Effect-based   Sensing of Xanthine Oxidase and its Inhibitors with Mn-doped ZnS Quantum   Dots. Nanoscale, 2018, 10, 8477-8482.

Scheme 1

 

9.         Hu, H.; He, H. W.; Zhang, J. Y.; Hou, X. D.; Wu, Peng*   Optical sensing at the Nanobiointerface of Metal Ion-Optically-Active   Nanocrystals. Nanoscale, 2018, 10, 5035-5046.

Figure 1

 

2017年:

1.         Hu, H.; Zhang, J.; Ding, Y.; Zhang, X.; Xu, K. L.*; Hou, X.; Wu,   Peng*; Modulation of the Singlet Oxygen Generation from the Double   Strand DNA-SYBR Green I Complex Mediated by T-Melamine-T Mismatch for Visual   Detection of Melamine. Anal. Chem. 2017, 89, 5101-5106.

TOC

 

2.         Li, C. B.; Xu, Q.; Xu, S. X.; Zhang, X. F.*; Hou, X. D.; Wu,   Peng* Synergy of Adsorption and Photosensitization of Graphene Oxide   for Improved Removal of Organic Pollutants. RSC Adv., 2017, 7,   16204-16209.

Scheme 1

 

3.         Zhang, J. Y.; Lu, X. M.; Lei, Y.; Hou, X. D.*; Wu, Peng*   Exploring Tunable Excitation of QDs to Maximize the Overlap with Absorber for   Inner Filter Effect-based Phosphorescent Sensing of Alkaline Phosphatase. Nanoscale,   2017, 9, 15606-15611.

 

4.         Cao, G.; Xu, F.; Wang, S.-L.; Xu, K. L.*; Hou, X.; Wu, Peng*;   Gold Nanoparticle-based Colorimetric Assay for Selenium Detection via Hydride   Generation. Anal. Chem., 2017, 89, 4695-4700.

TOC

 

2016年:

1.         Xu, S. X.; Li, X. M.; Li, C. B.; Li, J. L.; Zhang, X. F.*; Wu,   Peng*; Hou, X. D. In Situ Generation and Consumption of H2O2   by Bienzyme-Quantum Dots Bioconjugates for Improved Chemiluminescence   Resonance Energy Transfer. Anal. Chem., 2016, 88, 6418-6424.

TOC

 

2.         He, H. W.; Li, C. H.; Tian Y. F.*; Wu, Peng*; Hou,   X. D. Phosphorescent Differential Sensing of Physiological Phosphates with   Lanthanide Ions-Modified Mn-Doped ZnCdS Quantum Dots. Anal. Chem.,   2016, 88, 5892-5897.

Scheme

 

3.         Wu, Peng;   Hou, X. D.; Xu, J.-J.*; Chen, H.-Y.* Ratiometric Fluorescent, Electrochemiluminescent,   and Photoelectrochemical Chemo/Biosensing based on Semiconductor Quantum   Dots. Nanoscale, 2016, 8, 8427-8442.

图片1

 

4.         Li, C. H.; Wu, Peng*; Hou, X. D.* Plasma-Assisted   Quadruple-Channel Optosensing of Proteins and Cells with Mn-Doped ZnS Quantum   Dots. Nanoscale, 2016, 8, 4291-4298.

 

5.         Xia, H.; Hu, J.; Tang, J.; Xu, K. L.; Hou, X. D.*; Wu,   Peng* A RGB-Type Quantum Dot-based Sensor Array for Sensitive Visual   Detection of Trace Formaldehyde in Air. Sci. Rep., 2016, 6,   36794.

Figure 5

 

2015年之前:

1.         Wu, Peng;   Xu, C. Y.; Hou, X. D.; Xu, J.-J.*; Chen, H.-Y.* Dual-emitting quantum dot   nanohybrid for imaging of latent fingerprints: simultaneous identification of   individuals and traffic light-type visualization of TNT. Chem. Sci.,   2015, 6, 4445-4450.

2.         Zhang, X. F.; Huang, C. P.; Xu, S. X.; Chen, J. B.; Zeng, Y.; Wu,   Peng*; Hou, X. D.* Photocatalytic Oxidation of TMB with the Double   Strand DNA-SYBR Green I Complex for Label-Free and Universal Colorimetric   Bioassay. Chem. Commun., 2015, 51, 14465-14468.

3.         Wu, Peng;   Pan, J.-B.; Li, X.-L.; Hou, X. D.; Xu, J.-J.*; Chen, H.-Y.* Long-Lived Charge   Carriers in Mn-doped CdS Quantum Dots for Photoelectrochemical Cytosensing. Chem.   Eur. J., 2015, 21, 5129-5135.

4.         Li, M.; Xu, C. Y.; Wu, L.*; Wu, Peng*; Hou, X. D.   Dually Enriched Cu:CdS@ZnS QDs with both Polyvinylpyrrolidone Twisting and   SiO2 Loading for Improved Cell Imaging. Chem. Commun., 2015,   51, 3552-3555.

5.         Xu, C. Y.; Zhou, R. H.; He, W. W.; Wu, L.; Wu, Peng*;   Hou, X. D. Fast Imaging of Eccrine Latent Fingerprints with Nontoxic Mn-Doped   ZnS QDs. Anal. Chem., 2014, 86, 3279-3283.

6.         Wu, Peng;   Hou, X. D.; Xu, J.-J.*; Chen, H.-Y.* Electrochemically-Generated versus   Photo-excited Luminescence from Semiconductor Nanomaterials: Bridging the   Valley between Two Worlds. Chem. Rev., 2014, 114, 11027-11059.

7.         Wu, Peng;   Zhao, T.; Zhang, J. Y.; Wu, L.; Hou, X. D.* Analyte-Activable Probe for   Protease Based on Cytochrome C-Capped Mn: ZnS Quantum Dots. Anal. Chem.,   2014, 86, 10078-10083.

8.         Wu, Peng;   Zhang, J. Y.; Wang, S. L.; Zhu, A. R.; Hou, X. D.* Sensing during In Situ   Growth of Mn-Doped ZnS QDs: A Phosphorescent Sensor for Detection of H2S in   Biological Samples. Chem. Eur. J., 2014, 20, 952-956.

9.         Wu, Peng;   Zhao, T.; Wang, S. L.; Hou, X. D.* Semiconductor quantum dots-based metal ion   probes. Nanoscale, 2014, 6, 43-64.

10.     Wu, Peng;   Yan, X.-P.* Doped quantum dots for chemo/biosensing and bioimaging. Chem.   Soc. Rev., 2013, 42, 5489-5521.

11.     Wu, Peng;   Zhao, T.; Tian, Y. F.; Wu, L.; Hou, X. D.* Protein-Directed Synthesis of   Mn-Doped ZnS Quantum Dots: A Dual-Channel Biosensor for Two Proteins. Chem.   Eur. J., 2013, 19, 7473-7479.

12.     Zhao, T.; Hou, X. D.; Xie, Y.-N.; Wu, L.*; Wu, Peng*   Phosphorescent sensing of Cr3+ with protein-functionalized Mn-doped ZnS   quantum dots. Analyst, 2013, 138, 6589-6594.

13.     Wu, Peng;   Miao, L.-N.; Wang, H.-F.; Shao, X.-G.; Yan, X.-P.* A multidimensional sensing   device for the discrimination of proteins based on manganese-doped ZnS   quantum dots. Angew. Chem. Int. Ed., 2011, 50, 8118-8121.

14.     Wu, Peng;   Yan, X.-P.* A simple chemical etching strategy to generate   "ion-imprinted" sites on the surface of quantum dots for selective   fluorescence turn-on detecting of metal ions. Chem. Commun., 2010,   46, 7046-7048.

15.     Wu, Peng;   Yan, X.-P.* Ni2+-modulated homocysteine-capped CdTe quantum dots   as a turn-on photoluminescent sensor for detecting histidine in biological   fluids. Biosens. Bioelectron., 2010, 26, 485-490.

16.     Wu, Peng;   He, Y.; Wang, H.-F.; Yan, X.-P.* Conjugation of glucose oxidase onto Mn-doped   ZnS quantum dots for phosphorescent sensing of glucose in biological fluids. Anal.   Chem., 2010, 82, 1427-1433.

17.     Wu, Peng;   He, L.; Zheng, C. B.; Hou, X. D.*; Sturgeon, R. E. Applications of chemical   vapor generation in non-tetrahydroborate media to analytical atomic   spectrometry. J. Anal. At. Spectrom., 2010, 25, 1217-1246.

18.     Wu, Peng;   Zhang, Y. C.; Liu, R.; Lv, Y.; Hou, X. D.* Comparison of tungsten coil   electrothermal vaporization and thermospray sample introduction methods for   flame furnace atomic absorption spectrometry. Talanta, 2009,   77, 1778-1782.

19.     Wu, Peng;   Li, Y.; Yan, X.-P.* CdTe quantum dots (QDs) based kinetic discrimination of   Fe2+ and Fe3+, and CdTe QDs-Fenton hybrid system for   sensitive photoluminescent detection of Fe2+. Anal. Chem.,   2009, 81, 6252-6257.

20.     Wu, Peng;   Chen, H.; Cheng, G. L.; Hou, X. D.* Exploring surface chemistry of   nano-TiO(2) for automated speciation analysis of Cr(III) and Cr(VI) in   drinking water using flow injection and ET-AAS detection. J. Anal. At.   Spectrom., 2009, 24, 1098-1104.

21.     Wu, Peng;   Wen, X. D.; He, L.; He, Y. H.; Chen, M. Z.; Hou, X. D.* Evaluation of   tungsten coil electrothermal vaporization-Ar/H-2 flame atomic fluorescence   spectrometry for determination of eight traditional hydride-forming elements   and cadmium without chemical vapor generation. Talanta, 2008,   74, 505-511.

22.     Wu, Peng;   Liu, R.; Berndt, H.; Lv, Y.; Hou, X. D.* Highly sensitive pneumatic   nebulization flame furnace atomic absorption spectrometry: complete sample   aerosol introduction and on-line preconcentration of cadmium by atom trap. J.   Anal. At. Spectrom., 2008, 23, 37-42.

23.     Wu, Peng;   Gao, Y.; Cheng, G. L.; Yang, W. S.; Lv, Y.*; Hou, X. D.* Selective   determination of trace amounts of silver in complicated matrices by   displacement-cloud point extraction coupled with thermospray flame furnace atomic   absorption spectrometry. J. Anal. At. Spectrom., 2008, 23,   752-757.

24.     Wu, Peng;   Zhang, Y. C.; Lv, Y.; Hou, X. D.* Cloud point extraction-thermospray flame   quartz furnace atomic absorption spectrometry for determination of ultratrace   cadmium in water and urine. Spectrochim. Acta Part B, 2006, 61,   1310-1314.

 

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