四川大学化学学院
师资力量

董顺喜     教 授、博导

研究方向:有机化学

联系方式:15719421858          Email:dongs@scu.edu.cn

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教育经历:

2004.092008.06 四川大学   化学专业 理学学士学位

2008.092013.06 四川大学   有机化学 理学博士学位 导师:冯小明

研究及工作经历:

2013.112016.02 德国亚琛工业大学   洪堡学者 (Carsten Bolm教授)

2016.072017.12 德国明斯特大学   博士后 (Gerhard Erker教授)

2018.01~至今 四川大学化学学院 特聘研究员

通讯地址:四川省成都市九眼桥望江路29号四川大学化学学院

主要研究方向

新型手性配体或催化剂的设计合成

稀土有机金属配合物催化

生物活性分子的高效合成

主要工作业绩

研究经历

董顺喜博士毕业于四川大学,师从冯小明教授,博士研究方向主要是手性胍类小分子催化剂的设计、合成及其在吖内酯参与的环化反应中的应用。2013作为洪堡学者赴德国亚琛工业大学Carsten Bolm教授课题组开展博士后研究工作,主要从事氨基酸衍生的pentathiepin设计合成以及手性氮杂环卡宾(NHC)催化不对称转化领域研究。2016年,加入德国明斯特大学Gerhard Erker课题组,开展主族元素有机化学研究,主要开展新型受阻Lewis酸碱对(FLP)的设计合成及其反应性研究。进入四川大学化学学院后,主要从事(1)手性双氮氧催化金属配合物催化;(2)新型手性稀土有机配合物催化剂设计合成及其在不对称CH官能化、氢元素化等反应中的应用研究。目前为止,已取得一系列创新性的研究成果, Chem. Soc. Rev., J. Am.   Chem. Soc., Angew. Chem. Int. Ed., Org. Lett., Chem. Commun., Chem. -Eur.   J. 以及 Dalton. Trans.   等刊物发表 SCI 论文30余篇,多篇工作被Synfacts杂志刊登并给予高度评价。其中以第一作者身份发表 SCI 论文8篇,(共同)通讯作者论文12

 

主要奖励及荣誉

2013 获德国洪堡学者博士后奖学金

2019 获四川省引进海内外高层次人才计划

2019 获四川大学双百人才工程” B计划

2019 获教育部高等学校科学研究优秀成果奖自然科学一等奖(排名第四)

2020 获四川大学青年科技学术带头人培育项目资助

2020 四川大学学术新人奖

2021 Thieme Chemistry Journals Award

代表性成果 (获奖成果、专著、论文、专利)

论文发表情况

(1) Xiao, W. L.; Mo, Y. H.; Guo, J.; Su, Z. S.; Dong, S. X.*; Liu, X. H.;   Feng, X. M.* Catalytic   Enantioselective Synthesis of Macrodiolides and their Application in Chiral   Recognition, Chem. Sci., 2021, DOI: 10.1039/D0SC06162J.

(2) Chen, Y. S.; Liu, Y.; Li, Z. J.; Dong,   S. X.*; Liu, X. H.; Feng, X. M.* Tandem   Insertion/[1,3]-Rearrangement: Highly Enantioselective Construction of a-Aminoketones, Angew. Chem. Int. Ed. 2020, 59, 8052.

(3) Wang, F.; Feng, L. L.; Dong,   S. X.*; Liu, X. H.; Feng, X. M.* Chiral N,N′-Dioxide–Iron(III)-Catalyzed   Asymmetric Sulfoxidation with Hydrogen Peroxide, Chem.   Commun. 2020, 56, 3233.

(4) Li, D. W.; Wang, S. J.; Ge, S. L.; Dong,   S. X.*; Feng, X. M. Asymmetric Synthesis   of Axially Chiral Anilides via Organocatalytic Atroposelective N-Acylation, Org. Lett. 2020, 22, DOI:   10.1021/acs.orglett.0c01581.

(5) Dong, S. X.; Daniliuc, C. G.;   Kehr, G.; Erker, G.* Formation of Active   Cyclic Five-membered   Frustrated Phosphane/Borane Lewis Pairs and their Cycloaddition Reactions, Chem. Eur. J. 2020, 26, 745.

(6) Luo, Y.; Zhang, H.; Wang, S. Y.; Zhou, Y. Q.; Dong, S. X.*; Feng, X. M.* Asymmetric   Catalytic Diverse Ring Opening/Cycloadditions of Cyclobutenones with (E)-Alkenyloxindoles   and (E)-Dioxopyrrolidines,   Org. Lett. 2020, 22, 2645.

(7) Ge, S. L.; Zhang, Y. Y.; Tan, Z.; Li, D. W.; Dong, S. X.*; Liu, X. H.;   Feng, X. M.*, Bimetallic   Catalytic Tandem Reaction of Acyclic Enynones: Enantioselective Access to   Tetrahydrobenzofuran Derivatives, Org.   Lett. 2020, 22, 3551. Highlighted   by Synfacts, 2020, 16, 0820

(8) Tang, Q.; Fu, K.; Ruan, P. R.; Dong,   S. X.*; Su, Z. S; Liu, X. H.; Feng, X. M.* Asymmetric   Catalytic Formal 1,4-Allylation of β,γ-Unsaturated α-Ketoesters via   Allylboration/Oxy-Cope Rearrangement,   Angew. Chem. Int. Ed. 2019, 58, 11846.

(9) Xiong, Q. Li, G. L.; Dong,   S. X.*; Liu, X. H.; Feng, X. M.*, Enantioselective   Synthesis of Hydrothiazole Derivatives via an Isocyanide-Based   Multicomponent Reaction, Org. Lett. 2019, 21, 8771.

(10) Liu, W.; Zhou, P. F.; Lang, J. W.; Dong,   S. X.*; Liu, X. H.; Feng, X. M.*, A   nickel(II)-catalyzed asymmetric intramolecular Alder-ene reaction of   1,7-dienes, Chem. Commun. 2019, 55,   4479.

(11) Li, X. Q.; Xiong, Q.; Guan, M. M.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Divergent   Synthesis of Enantioenriched β-Functional Amines via Desymmetrization of   meso-Aziridines with Isocyanides, Org.   Lett. 2019, 21, 6096.

(12) Dong, S. X.; Feng, X. M.; Liu, X. H.* Chiral   Guanidine and Their Derivatives

in   Asymmetric Synthesis, Chem. Soc. Rev. 2018,   47, 8525.

(13) Zhong, X.; Tang, Q., Zhou, P. F.; Zhong, Z. W. Dong, S. X.*;   Liu, X. H.; Feng, X. M.*, Asymmetric   Synthesis of Polysubstituted Methylenecyclobutanes via Catalytic [2+2]   Cycloaddition Reaction of N-Allenamides, Chem.   Commun. 2018, 54, 10511.

(14) Dong, S. X.; Frings, M.; Cheng,   H. C.; Wen, J.; Zhang, D.; Rabbe, G.; Bolm, C.* "Organocatalytic   Kinetic Resolution of Sulfoximines"   J. Am. Chem. Soc. 2016, 138, 2166. Highlight by Synfacts   (2016, 634)

Abstract Image

(15) Dong, S. X.; Liu X. H*.; Zhu,   Y.; He, P.; Lin, L. L.; Feng, X. M.* "Organocatalytic   Oxyamination of Azlactones: Kinetic Resolution of Oxaziridines and   Asymmetric Synthesis of Oxazolin-4-ones"   J. Am. Chem. Soc. 2013, 135, 10026. Highlight by Synfacts   (2013, 1006)

(16) Dong, S. X.; Liu, X. H.; Chen,   X. H.; Mei, F.; Gao, B.; Lin, L. L.; Feng, X. M.* "Chiral   Bisguanidine-Catalyzed Inverse-Electron-Demand Hetero-Diels-Alder Reaction   of Chalcones with Azlactones" J. Am.   Chem. Soc. 2010, 132, 10650. Highlight by Synfacts   (2010, 1105)

(17) Dong, S. X.; Frings, M.; Zhang,   D.; Guo. Q. Q.; Danilliuc, C. G.; Cheng, H. C.; Bolm, C.* "Organocatalytic   Asymmetric Synthesis of trans-γ-Lactams"   Chem. Eur. J. 2017, 23, 13888.

(18) Dong, S. X.; Wang, L.; Wang, T.;   Daniliuc, C. G.; Brinkkötter, M.; Eckert, H.; Kehra. G.; Erker, G. "Formation   and Reactions of Active Five-membered Phosphane/borane Frustrated Lewis Pair   Ring Systems" Dalton Trans. 2018,   47, 4449.

(19) Dong, S. X.; Liu, X. H*.; Zhang,   Y. L.; Lin, L. L.; Feng, X. M *. "Asymmetric   Synthesis of 3,4-Diaminochroman-2-ones Promoted by Guanidine and   Bisguanidium Salt" Org. Lett. 2011,   13, 5060.

(20) Liu, X. H.; Dong, S. X.; Lin, L. L.; Feng, X. M.*   " Chiral   Amino Acids-Derived Catalysts and Ligands   " Chin. J. Chem, 2018, 36, 791.

(21) Guo, J.; Dong, S. X.; Zhang, Y. L.; Kuang, Y. L.; Feng,   X. M.* "Chiral   Scandium(III)-Catalyzed Enantioselective α-Arylation of N-Unprotected   3-Substituted Oxindoles with Diaryliodonium Salts" Angew. Chem., Int. Ed. 2013, 52,   10245. Highlight by Synfacts (2013, 1262)

(22) Wang, L.; Dong, S. X.; Daniliuc, C. G.; Liu, L.;   Grimme, S.; Knitsch, R.; Eckert, H.; Hansen, M. R.; Kehra. G.; Erker,   G."Formation   of Macrocyclic Ring Systems by Carbonylation of Trifunctional P/B/B Frustrated   Lewis Pairs" Chem. Sci. 2018, 9,   1544.

(23) Xu, X.; Zhang, J. L.; Dong, S. X.; Lin. L. L.; Lin, X.   B.; Liu, X. H.; Feng, X. M.* "Nickel(II)-Catalyzed   Asymmetric Propargyl [2,3]-Wittig Rearrangement of Oxindole Derivatives: A   Remarkable Chiral Amplification Effect"   Angew. Chem., Int. Ed. 2018, 57, 8734.

(24) Zhu, Y.; Liu, X. H.;* Dong, S. X.; Zhou, Y. H.; Li, W.;   Lin, L. L.; Feng, X. M.* "Asymmetric   N-H Insertion of Secondary and Primary Anilines under the Catalysis of   Palladium and Chiral Guanidine Derivatives"   Angew. Chem., Int. Ed. 2014, 53, 1636.

(25) Wen, J.; Cheng, H. C.; Dong, S. X.; Bolm, C.* "Copper-Catalyzed   S-C/S-N Bond Interconversions" Chem. Eur.   J. 2016, 22, 5547.

(26) Chen, X. Y.; Bohmann, R. A.; Wang, L.; Dong, S. X.;   Räuber, C.; Bolm, C.* "Palladium/Copper-Cocatalyzed   Oxidative Amidobrominations of Alkenes"   Chem. Eur. J. 2015, 21, 10330.

(27) Cheng, H.; Dong, W.; Dannenberg, C. A.; Dong, S. X.;   Guo, Q.; Bolm, C.* "Ruthenium-Catalyzed   Hydroarylations of Oxa- and Azabicyclic Alkenes"   ACS Cat. 2015, 5, 2770.

(28) Yao, Q.; Yu, H.; Zhang, H.; Dong, S. X.; Chang, F. Z.;   Lin, L. L.; Liu, X. H.; Feng, X. M.* "Lewis   acid catalyzed asymmetric [4+2] cycloaddition of cyclobutenones to   synthesize α,β-unsaturated δ-lactones"   Chem. Commun. 2018, 54, 3375.

(29) Chen, X. H.; Dong, S. X.; Qiao, Z.; Zhu, Y.; Xie, M. S.; Lin,   L. L.; Liu, X. H.;* Feng, X. M.* "Guanidine   Organocatalyst for Asymmetric Mannich-Type Reaction between α-Isothiocyanato   Imide and Sulfonyl Imines" Chem. Eur.   J. 2011, 17, 2583.

(30) Zhang, Y. L.; Dong, S. X.; Liu, X. H.; Xie. M. S.; Zhu,   Y.; Lin, L. L.; Feng, X. M.* "Asymmetric   Synthesis of cis-4-Aminobenzopyran Derivatives Catalyzed by N,N'-Dioxide-Sc(OTf)3   Complex" Chem. Eur. J. 2011, 17, 13684.

(31) Yang, Y.; Dong, S. X.; Liu, X. H.; Lin, L. L.; Feng, X.   M.* "Chiral   guanidine-catalyzed asymmetric direct vinylogous Michael reaction of   α,β-unsaturated γ-butyrolactams with alkylidene malonates" Chem. Commun., 2012, 48, 5040.

(32) Xiao, X.; Liu X. H*.; Dong, S. X.; Cai, Y.   F.; Lin, L. L.; Feng, X. M.* "Asymmetric   Synthesis of 2,3-Dihydroquinolin-4-one Derivatives Catalyzed by Chiral   Bisguanidium Salt" Chem. Eur. J.   2012, 18, 15922.

(33) Zhu, Y.; Xie, M. S.; Dong,   S. X.; Zhao, X. H.; Lin, L. L.; Liu, X. H.; Feng, X. M.*   "Asymmetric   Cycloaddition of β,γ-Unsaturated α-Ketoesters with Electron-Rich Alkenes   Catalyzed by a Chiral Er(OTf)3/N,N′-Dioxide Complex:   Highly Enantioselective Synthesis of 3,4-Dihydro-2H-pyrans" Chem. Eur. J. 2011, 17, 8202.

(34) Wang, J.; Liu, X. H.;* Dong, S. X.; Lin, L. L.; Feng, X. M.* "Asymmetric   Organocatalytic Cyclopropanation of Cinnamone Derivatives with Stabilized   Sulfonium Ylides" J. Org. Chem.,   2013, 78, 6322.

(35) Xiong, Y.; Wang, F.; Dong,   S. X.; Liu, X. H.; Feng, X. M.* "Asymmetric   Bisprolinamide-Catalyzed Cross-Aldol Reaction of Aldehydes" Synlett. 2008, 1, 73.

(36) Zhu, Y.; Chen, X. H.; Xie, M. S.; Dong, S. X.; Qiao, Zhen.; Lin, L.   L.; Liu, X. H.; Feng, X. M.* "Asymmetric   Diels–Alder and Inverse-Electron-Demand Hetero-Diels–Alder Reactions of   β,γ-Unsaturated α-Ketoesters with Cyclopentadiene Catalyzed by N,N′-Dioxide   Copper(II) Complex" Chem. Eur. J. 2010,   16, 11963.

(37) Wen, Y. H.; Gao, B.; Fu, Y. Z.; Dong,   S. X.; Liu, X. H.; Feng, X. M.* "Asymmetric   Three-Component Strecker Reactions Catalyzed by trans-4-Hydroxy-L-proline-Derived   N,N′-Dioxides" Chem. Eur.   J. 2008, 14, 6789.

 

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