四川大学化学学院
师资力量

董顺喜     教 授、博导

研究方向:有机化学

联系方式:          Email:dongs@scu.edu.cn

个人主页:点击进入

简历:

教育经历:

2004.092008.06 四川大学  化学专业  理学学士学位 

2008.092013.06 四川大学  有机化学  理学博士学位  导师:冯小明

研究及工作经历:

2013.112016.02 德国亚琛工业大学,洪堡学者  (Carsten Bolm教授)

2016.072017.12 德国明斯特大学,博士后  (Gerhard Erker教授)

2018.012021.08 四川大学,化学学院,特聘研究员

2021.09~至今 四川大学,化学学院,教授

通讯地址:四川省成都市九眼桥望江路29号四川大学化学学院

主要研究方向

新型手性配体或催化剂的设计合成

稀土有机金属配合物催化

生物活性分子的高效合成

主要工作业绩

研究经历

董顺喜博士毕业于四川大学,师从冯小明教授,博士研究方向主要是手性胍类小分子催化剂的设计、合成及其在吖内酯参与的环化反应中的应用。2013作为洪堡学者赴德国亚琛工业大学Carsten Bolm教授课题组开展博士后研究工作,主要从事氨基酸衍生的pentathiepin设计合成以及手性氮杂环卡宾(NHC)催化不对称转化领域研究。2016年,加入德国明斯特大学Gerhard Erker课题组,开展主族元素有机化学研究,主要开展新型受阻Lewis酸碱对(FLP)的设计合成及其反应性研究。进入四川大学化学学院后,主要从事(1)手性双氮氧金属配合物催化;(2)新型手性稀土有机配合物催化剂设计合成及其在不对称CH官能化、氢元素化等反应中的应用研究。截至目前,已取得一系列创新性的研究成果, Acc. Chem. Res., Chem. Soc. Rev., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Org. Lett., Chem. Commun., Chem. -Eur. J. 以及 Dalton. Trans. 等刊物发表 SCI 论文40余篇,多篇工作被Synfacts杂志刊登并给予高度评价。其中以第一作者身份发表 SCI 论文9篇,(共同)通讯作者论文17篇。

主要奖励和荣誉  

2013 获德国洪堡学者博士后奖学金

2019 获四川省引进海内外高层次人才计划

2019 获四川大学双百人才工程” B计划

2019 获教育部高等学校科学研究优秀成果奖自然科学一等奖(排名第四)

2020 获四川大学青年科技学术带头人培育项目资助

2020 四川大学学术新人奖

2021 Thieme Chemistry Journals Award

2021 第十三批四川省学术与技术带头人后备人选

学术任职

2022年~2025 Chinese Chemical Letters 第四届青年编委会委员

代表性成果 (获奖成果、专著、论文、专利)

1. Dong, S. X.; Liu, X. H.,* Feng, X. M.,* Asymmetric Catalytic Rearrangements with α-Diazocarbonyl Compounds, Acc. Chem. Res. 2022, 55, 415428 (封面文章).

2. Wang, Y.; Yihuo, A. Y.; Wang, L. F. Dong, S. X.*; Feng, X. M.* Catalytic Asymmetric Synthesis of Chiral Azo Compounds via Interrupted Japp–Klingemann Reaction with Aryldiazonium Salts, Sci. China Chem. 2022, 65, 546.

3. Zhong, X.; Tan, J. Q.; Qiao, J. L.; Zhou, Y. Q.; Lv, C. D.; Su, Z. S.; Dong, S. X.*; Feng, X. M.* Catalytic Asymmetric Synthesis of Spirocyclobutyl Oxindoles and Beyond via [2+2] Cycloaddition and Sequential Transformations, Chem. Sci. 2021, 12, 9991−9997.

4. Xu, C. R.; Qiao, J. L.; Dong, S. X.*; Zhou, Y. Q.; Liu, X. H.; Feng, X. M.* Asymmetric Synthesis of Dihydro-1,3-Dioxepines by Rh(II)/Sm(III) Relay Catalytic Three-Component Tandem [4+3]-Cycloaddition, Chem. Sci., 2021, 12, 5458.

5. Xiao, W. L.; Mo, Y. H.; Guo, J.; Su, Z. S.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Catalytic Enantioselective Synthesis of Macrodiolides and their Application in Chiral Recognition, Chem. Sci., 2021, 12, 2940.

6. Xiong, Q.; Luo, Q. L.; Zhang, T. H.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Catalytic Asymmetric Multicomponent Reaction of Isocyanide, Isothiocyanate and Alkylidene Malonates, Chem. Commun., 2021, 57, 7288.

7. Tang, X. X.; Su, Z. S., Yan, L. Q.; Tang, Q.; Dong, S. X.;* Lili Lin, Xiaoming Feng*, Diastereo- and Enantioselective Synthesis of 3 Allyl-3-hydroxyoxindoles via Allylation of Isatins, Org. Lett. 2021, 23, 8419.

8. Dong, P.; Chen, L.; Yang, Z. D.; Dong, S. X.*; Xiaoming Feng*, Asymmetric Cycloisomerization/[3+2] Cycloaddition for Synthesis of Chiral Spiroisobenzofuran-1,3'-pyrrolidine Derivatives, Org. Chem. Front. 2021, 8, 6874.

9. Chen, Y. S.; Liu, Y.; Li, Z. J.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Tandem Insertion/[1,3]-Rearrangement: Highly Enantioselective Construction of a-Aminoketones, Angew. Chem. Int. Ed. 2020, 59, 8052.

10. Wang, F.; Feng, L. L.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Chiral N,N-DioxideIron(III)-Catalyzed Asymmetric Sulfoxidation with Hydrogen Peroxide, Chem. Commun. 2020, 56, 3233.

11. Li, D. W.; Wang, S. J.; Ge, S. L.; Dong, S. X.*; Feng, X. M. Asymmetric Synthesis of Axially Chiral Anilides via Organocatalytic Atroposelective N-Acylation, Org. Lett. 2020, 22, 5331.

12. Dong, S. X.; Daniliuc, C. G.; Kehr, G.; Erker, G.* Formation of Active Cyclic Five-membered Frustrated Phosphane/Borane Lewis Pairs and their Cycloaddition Reactions, Chem. Eur. J. 2020, 26, 745.

13. Luo, Y.; Zhang, H.; Wang, S. Y.; Zhou, Y. Q.; Dong, S. X.*; Feng, X. M.* Asymmetric Catalytic Diverse Ring Opening/Cycloadditions of Cyclobutenones with (E)-Alkenyloxindoles and (E)-Dioxopyrrolidines, Org. Lett. 2020, 22, 2645.

14. Ge, S. L.; Zhang, Y. Y.; Tan, Z.; Li, D. W.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Bimetallic Catalytic Tandem Reaction of Acyclic Enynones: Enantioselective Access to Tetrahydrobenzofuran Derivatives, Org. Lett. 2020, 22, 3551. Highlighted by Synfacts, 2020, 16, 0820

15. Tang, Q.; Fu, K.; Ruan, P. R.; Dong, S. X.*; Su, Z. S; Liu, X. H.; Feng, X. M.* Asymmetric Catalytic Formal 1,4-Allylation of β,γ-Unsaturated α-Ketoesters via Allylboration/Oxy-Cope Rearrangement, Angew. Chem. Int. Ed. 2019, 58, 11846.

16. Xiong, Q. Li, G. L.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Enantioselective Synthesis of Hydrothiazole Derivatives via an Isocyanide-Based Multicomponent Reaction, Org. Lett. 2019, 21, 8771.

17. Liu, W.; Zhou, P. F.; Lang, J. W.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, A nickel(II)-catalyzed asymmetric intramolecular Alder-ene reaction of 1,7-dienes, Chem. Commun. 2019, 55, 4479.

18. Li, X. Q.; Xiong, Q.; Guan, M. M.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Divergent Synthesis of Enantioenriched β-Functional Amines via Desymmetrization of meso-Aziridines with Isocyanides, Org. Lett. 2019, 21, 6096.

19. Dong, S. X.; Feng, X. M.; Liu, X. H.* Chiral Guanidine and Their Derivatives in Asymmetric Synthesis, Chem. Soc. Rev. 2018, 47, 8525.

20. Zhong, X.; Tang, Q., Zhou, P. F.; Zhong, Z. W. Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Asymmetric Synthesis of Polysubstituted Methylenecyclobutanes via Catalytic [2+2] Cycloaddition Reaction of N-Allenamides, Chem. Commun. 2018, 54, 10511.

21. Dong, S. X.; Frings, M.; Cheng, H. C.; Wen, J.; Zhang, D.; Rabbe, G.; Bolm, C.* "Organocatalytic Kinetic Resolution of Sulfoximines" J. Am. Chem. Soc. 2016, 138, 2166. Highlight by Synfacts (2016, 634)

22. Dong, S. X.; Liu X. H*.; Zhu, Y.; He, P.; Lin, L. L.; Feng, X. M.* "Organocatalytic Oxyamination of Azlactones: Kinetic Resolution of Oxaziridines and Asymmetric Synthesis of Oxazolin-4-ones" J. Am. Chem. Soc. 2013, 135, 10026. Highlight by Synfacts (2013, 1006)

23. Dong, S. X.; Liu, X. H.; Chen, X. H.; Mei, F.; Gao, B.; Lin, L. L.; Feng, X. M.* "Chiral Bisguanidine-Catalyzed Inverse-Electron-Demand Hetero-Diels-Alder Reaction of Chalcones with Azlactones" J. Am. Chem. Soc. 2010, 132, 10650. Highlight by Synfacts (2010, 1105)

24. Dong, S. X.; Frings, M.; Zhang, D.; Guo. Q. Q.; Danilliuc, C. G.; Cheng, H. C.; Bolm, C.* "Organocatalytic Asymmetric Synthesis of trans-γ-Lactams" Chem. Eur. J. 2017, 23, 13888.

25. Dong, S. X.; Wang, L.; Wang, T.; Daniliuc, C. G.; Brinkkötter, M.; Eckert, H.; Kehra. G.; Erker, G. "Formation and Reactions of Active Five-membered Phosphane/borane Frustrated Lewis Pair Ring Systems" Dalton Trans. 2018, 47, 4449.

26. Dong, S. X.; Liu, X. H*.; Zhang, Y. L.; Lin, L. L.; Feng, X. M *. "Asymmetric Synthesis of 3,4-Diaminochroman-2-ones Promoted by Guanidine and Bisguanidium Salt" Org. Lett. 2011, 13, 5060.

27. Liu, X. H.; Dong, S. X.; Lin, L. L.; Feng, X. M.* " Chiral Amino Acids-Derived Catalysts and Ligands " Chin. J. Chem, 2018, 36, 791.

28. Guo, J.; Dong, S. X.; Zhang, Y. L.; Kuang, Y. L.; Feng, X. M.* "Chiral Scandium(III)-Catalyzed Enantioselective α-Arylation of N-Unprotected 3-Substituted Oxindoles with Diaryliodonium Salts" Angew. Chem., Int. Ed. 2013, 52, 10245. Highlight by Synfacts (2013, 1262)

29. Wang, L.; Dong, S. X.; Daniliuc, C. G.; Liu, L.; Grimme, S.; Knitsch, R.; Eckert, H.; Hansen, M. R.; Kehra. G.; Erker, G."Formation of Macrocyclic Ring Systems by Carbonylation of Trifunctional P/B/B Frustrated Lewis Pairs" Chem. Sci. 2018, 9, 1544.

30. Xu, X.; Zhang, J. L.; Dong, S. X.; Lin. L. L.; Lin, X. B.; Liu, X. H.; Feng, X. M.* "Nickel(II)-Catalyzed Asymmetric Propargyl [2,3]-Wittig Rearrangement of Oxindole Derivatives: A Remarkable Chiral Amplification Effect" Angew. Chem., Int. Ed. 2018, 57, 8734.

31. Zhu, Y.; Liu, X. H.;* Dong, S. X.; Zhou, Y. H.; Li, W.; Lin, L. L.; Feng, X. M.* "Asymmetric N-H Insertion of Secondary and Primary Anilines under the Catalysis of Palladium and Chiral Guanidine Derivatives" Angew. Chem., Int. Ed. 2014, 53, 1636.

32. Wen, J.; Cheng, H. C.; Dong, S. X.; Bolm, C.* "Copper-Catalyzed S-C/S-N Bond Interconversions" Chem. Eur. J. 2016, 22, 5547.

33. Chen, X. Y.; Bohmann, R. A.; Wang, L.; Dong, S. X.; Räuber, C.; Bolm, C.* "Palladium/Copper-Cocatalyzed Oxidative Amidobrominations of Alkenes" Chem. Eur. J. 2015, 21, 10330.

34. Cheng, H.; Dong, W.; Dannenberg, C. A.; Dong, S. X.; Guo, Q.; Bolm, C.* "Ruthenium-Catalyzed Hydroarylations of Oxa- and Azabicyclic Alkenes" ACS Cat. 2015, 5, 2770.

35. Yao, Q.; Yu, H.; Zhang, H.; Dong, S. X.; Chang, F. Z.; Lin, L. L.; Liu, X. H.; Feng, X. M.* "Lewis acid catalyzed asymmetric [4+2] cycloaddition of cyclobutenones to synthesize α,β-unsaturated δ-lactones" Chem. Commun. 2018, 54, 3375.

36. Chen, X. H.; Dong, S. X.; Qiao, Z.; Zhu, Y.; Xie, M. S.; Lin, L. L.; Liu, X. H.;* Feng, X. M.* "Guanidine Organocatalyst for Asymmetric Mannich-Type Reaction between α-Isothiocyanato Imide and Sulfonyl Imines" Chem. Eur. J. 2011, 17, 2583.

37. Zhang, Y. L.; Dong, S. X.; Liu, X. H.; Xie. M. S.; Zhu, Y.; Lin, L. L.; Feng, X. M.* "Asymmetric Synthesis of cis-4-Aminobenzopyran Derivatives Catalyzed by N,N'-Dioxide-Sc(OTf)3 Complex" Chem. Eur. J. 2011, 17, 13684.

38. Yang, Y.; Dong, S. X.; Liu, X. H.; Lin, L. L.; Feng, X. M.* "Chiral guanidine-catalyzed asymmetric direct vinylogous Michael reaction of α,β-unsaturated γ-butyrolactams with alkylidene malonates" Chem. Commun., 2012, 48, 5040.

39. Xiao, X.; Liu X. H*.; Dong, S. X.; Cai, Y. F.; Lin, L. L.; Feng, X. M.* "Asymmetric Synthesis of 2,3-Dihydroquinolin-4-one Derivatives Catalyzed by Chiral Bisguanidium Salt" Chem. Eur. J. 2012, 18, 15922.

40. Zhu, Y.; Xie, M. S.; Dong, S. X.; Zhao, X. H.; Lin, L. L.; Liu, X. H.; Feng, X. M.* "Asymmetric Cycloaddition of β,γ-Unsaturated α-Ketoesters with Electron-Rich Alkenes Catalyzed by a Chiral Er(OTf)3/N,N-Dioxide Complex: Highly Enantioselective Synthesis of 3,4-Dihydro-2H-pyrans" Chem. Eur. J. 2011, 17, 8202.

41. Wang, J.; Liu, X. H.;* Dong, S. X.; Lin, L. L.; Feng, X. M.* "Asymmetric Organocatalytic Cyclopropanation of Cinnamone Derivatives with Stabilized Sulfonium Ylides" J. Org. Chem., 2013, 78, 6322.

42. Xiong, Y.; Wang, F.; Dong, S. X.; Liu, X. H.; Feng, X. M.* "Asymmetric Bisprolinamide-Catalyzed Cross-Aldol Reaction of Aldehydes" Synlett. 2008, 1, 73.

43. Zhu, Y.; Chen, X. H.; Xie, M. S.; Dong, S. X.; Qiao, Zhen.; Lin, L. L.; Liu, X. H.; Feng, X. M.* "Asymmetric DielsAlder and Inverse-Electron-Demand Hetero-DielsAlder Reactions of β,γ-Unsaturated α-Ketoesters with Cyclopentadiene Catalyzed by N,N-Dioxide Copper(II) Complex" Chem. Eur. J. 2010, 16, 11963.

44. Wen, Y. H.; Gao, B.; Fu, Y. Z.; Dong, S. X.; Liu, X. H.; Feng, X. M.* "Asymmetric Three-Component Strecker Reactions Catalyzed by trans-4-Hydroxy-L-proline-Derived N,N-Dioxides" Chem. Eur. J. 2008, 14, 6789.

 

 

关闭