四川大学化学学院
师资力量

赵南蓉     教 授(博导)

研究方向:物理化学

联系方式:18628002677          Email:zhaonanr@scu.edu.cn

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简历:

学习经历

1991-1998:西南大学,物理科学与技术学院,本科,硕士

1998-2001:四川大学,化学学院,博士

工作经历

2001-2002:四川大学,物理科学与技术学院,副教授

2002-2003:德国柏林工业大学,博士后

2004-2007:日本名古屋工业大学,博士后

2008-至今:四川大学,化学学院,教授,博士生导师

主要研究方向

采用理论及计算机模拟的方法,探索生物体系中动力学过程的物理化学机制,发展复杂体系统计力学的研究:

1. 活性生物体系中大分子折叠、环化及反应速率过程

2. 聚合物溶液中蛋白扩散及反应动力学

3. 纳米聚合物复合体系的界面效应

4. 针对单分子拉伸力实验的介观统计理论

5. 酶构型涨落及单分子酶反应动力学

主要工作业绩

1. 国家自然科学基金(面上):活性生物体系扩散-反应动力学的介观统计理论研究,2019.01-2022.12

2. 四川省应用基础研究(重点):细胞中蛋白结构、功能与稳定性研究,2018.01-2020.12

3. 国家自然科学基金(面上):亚浓聚合物溶液中蛋白扩散及反应动力学的介观统计理论研究,2017.01-2020.12

4. 国家自然科学基金(面上):拉伸力作用下大分子构象变化动力学的介观统计理论研究,2014.01-2017.12

5. 四川省应用基础计划:生物单分子检测技术的研究及应用,2014.07-2016.06

6. 国家自然科学基金(面上):蛋白质环境效应的介观非马尔可夫统计模型研究,2012.01-2015.12

7. 教育部新世纪优秀人才支持计划:酶构型及反应动力学的介观统计研究,2012.01-2014.12

8. 四川大学优秀青年学者基金:酶构型及反应动力学的非平衡统计研究,2011.03-2013.12

9. 四川省国际合作计划:非平衡热力学在几类典型生物体系中的应用,2011.01-2013.12

10. 国家自然科学基金(面上):酶构型涨落及单分子酶反应动力学的介观统计理论,2010.01-2012.12

11. 教育部留学回国人员科研启动基金:粘滞-耗散效应对流体反应系统化学热力学行为的影响,2009.01-2011.12

主要奖励和荣誉

1. 2004年:日本学术振兴会(JSPS)博士后基金

2. 2011年:教育部新世纪优秀人才支持计划

3. 2012年:四川大学优秀青年学者科研基金

4. 2013年:四川省学术和技术带头人后备人选

5. 2017年:四川大学十佳师德奖

6. 2018年:四川大学第四届星火校友奖教金 

代表性成果 (获奖成果、专著、论文、专利)

1. B. J. Zhang, T. Lei and N. R. Zhao*, Comparative study of polymer looping kinetics in passive and active environments, Phys. Chem. Chem. Phys. 23, 12171 (2021).

2.  F. Tan, Y. Chen and N. R. Zhao*, Effects of active crowder size and activity–crowding coupling on polymer translocation, Soft Matter 17, 1940 (2021).

3.  B. J. Zhang, F. Tan and N. R. Zhao*, Polymer looping kinetics in active heterogeneous environments, Soft Matter 17, 10334 (2021).

4.  F. E. Feng, T. Lei and N. R. Zhao*, Tunable depletion force in active and crowded environments, Phys. Rev. E 103, 022604 (2021).

5. A. P. Chen, B. J. Zhang and N. R. Zhao*A comparative study of semi-flexible linear and ring polymer conformational change in an anisotropic environment, Phys. Chem. Chem. Phys. 22, 9137 (2020)

 

6. B. J. Zhang, R. Yan, and N. R. Zhao*,? Dynamics and glass transition temperature of polystyrene films supported on hydroxyl terminated substrates, AIP Advances???? 10, 045322 (2020)

 

7.  X. L. Cao, B. J. Zhang and N. R. Zhao*, Effective temperature scaled dynamics of a flexible polymer in an active bath. Mol. Phys. e1730992 (2020)

 

8.  X. L. Cao, B. J. Zhang and N. R. Zhao*, Contrastive factors of activity and crowding on conformational properties of a flexible polymer, Chem. Phys. Lett. 745, 137213 (2020)

9. C.L. Yuan, A.P. Chen, B.J. Zhang and N. R. Zhao*, Activity-crowding coupling effect on diffusion dynamics of a self-propelled particle in polymer solutions, Phy. Chem. Chem. Phys. 21, 24112 (2019)

10. X. L. Cao, B. J. Zhang and N. R. Zhao*, Crowding-Activity Coupling Effect on Conformational Change of a Semi-Flexible Polymer, Polymers 11, 1021 (2019).

11. Y. K. Bian, R. Yan, P. Li and N. R. Zhao*, Unusual crowding-induced chain looping kinetics in hard-sphere fluids: a contrastive study with polymer solutions, Soft Matter 15, 4976 (2019).

12. A. P. Chen and N. R. Zhao*, Comparative study of the crowding-induced collapse effect in hard-sphere, flexible polymer and rod-like polymer systems, Phy. Chem. Chem. Phys. 21, 12335 (2019).

13. Y. K. Bian, X. L. Cao, P. Li and N. R. Zhao*, Understanding chain looping kinetics in polymer solutions: crowding effects of microviscosity and collapse, Soft Matter 14, 8060 (2018).

14. B. J. Zhang, X. L. Cao, G. Zhou* and N. R. Zhao*, Anomalous diffusion of polystyrene from an attractive substrate based on all-atom simulation, Phys. Chem. Chem. Phys. 20, 25304 (2018).

15. J. Qing, A. P. Chen and N. R. Zhao*, Quantifying the protein–protein association rate in polymer solutions: crowding-induced diffusion and energy modifications, Phys. Chem. Chem. Phys. 20, 27937 (2018). 

16. A. P. Chen, N. R. Zhao* and Z. H. Hou*, The effect of hydrodynamic interactions on nanoparticle diffusion in polymer solutions: a multiparticle collision dynamics study, Soft Matter 13, 8625 (2017).

17. J. Wang, Y. K. Bian, X. L. Cao and N. R. Zhao*, Understanding diffusion of intrinsically disordered proteins in polymer solutions: A disorder plus collapse model, AIP Advances 7, 115120 (2017).

18. J. Qing, A. P. Chen and N. R. Zhao*, A new scaling for the rotational diffusion of molecular probes in polymer solutions, Phys. Chem. Chem. Phys. 19, 32687 (2017).

19. X. Q. Feng, A. P. Chen, J. Wang, N. R. Zhao* and Z. H. Hou*, Understanding protein diffusion in polymer solutions: a hydration with depletion model, J. Phys. Chem. B 120, 10114 (2016).

20.Y. H. Dong, X. Q. Feng, N. R. Zhao* and Z. H. Hou*, Diffusion of nanoparticles in semidilute polymer solutions: A mode-coupling theory study, J. Chem. Phys. 143, 024903 (2015).21. Y. K. Bian, Z. L. Wang, A. P. Chen and N. R. Zhao*, Fluctuating bottleneck model studies on kinetics of DNA escape from α-hemolysin nanopores, J. Chem. Phys. 143, 184908 (2015).

22. P. Li, Y. H. Dong, N. R. Zhao* and Z. H. Hou*, Distance fluctuation of a single molecule in Lennard-Jones liquid based on generalized Langevin equation and mode coupling theory, J. Chem. Phys. 140, 154109 (2014).

23. Y. Zheng, Y. K. Bian, N. R. Zhao* and Z. H. Hou*, Stretching of single poly-ubiquitin molecules revisited: Dynamic disorder in the nonexponential unfolding kinetics, J. Chem. Phys. 140, 125102 (2014).

 

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