四川大学化学学院
师资力量

刘小华     教授(博导)

研究方向:不对称合成

联系方式:          Email:liuxh@scu.edu.cn

个人主页:点击进入

简历:

1996.9-2000.6 湖北师范学院化学系学习,获理学学士学位。

2000.9-2003.6 四川大学化学学院分析化学专业学习,获理学硕士学位。

2003.9-2006.6 四川大学化学学院有机化学专业学习,获理学博士学位。

2006.7-2010.6 四川大学化学学院副教授,硕士生导师。

2010.7-至今   四川大学化学学院教授,2012年担任博士生导师。

2011年获教育部新世纪优秀人才计划资助;2012年获国家自然科学基金委优秀青年基金资助;2013年入选四川省学术和技术带头人后备人选;获霍英东青年教师基金资助;2015年入选第二届国家高层次人才特殊支持计划青年人才,享受国务院政府特殊津贴专家;2016年获国家杰出青年科学基金资助;2017年国家百千万人才工程入选者和有突出贡献中青年专家;2018年入选四川省学术和技术带头人;2020年获全国三八红旗手称号;2021年当选英国皇家化学会会士。

Organic & Biomolecular Chemistry副主编,Chinese Chemical Letter和《化学学报》编委委员,《高等学校化学学报》青年执行编委,中国化学会青年工作委员会委员、中国化学会有机化学学科委员、手性化学专业委员会副主任和物理有机化学专业委员会委员。

主要研究方向

主要从事新型手性催化剂的设计合成、不对称催化反应、手性药物和生理活性化合物的高效高选择性合成研究。详见课题组主页http://www.scu.edu.cn/chem_asl

主要工作业绩

主要从事不对称合成方法学及生理活性化合物的合成研究。目前研究工作集中在新型手性含氮类配体和催化剂的设计合成、不对称催化反应、生理活性化合物合成及催化机理研究。

2009年获教育部高等学校科学研究优秀成果奖自然科学一等奖(第二完成人);2012年获国家自然科学奖二等奖(第二完成人);2013年获德国Thieme出版社Thieme Chemistry Journals Award 2013;2014年获四川大学“唐立新青年科技之星奖”一等奖;2016年获Asian Core Program / Advanced Research Network Lectureship Award;2016年获四川大学青年科技人才奖;2018年获第六届中国化学会-英国皇家化学会青年化学奖;2019年获第十五届中国青年女科学家奖;2019年获教育部高等学校科学研究优秀成果奖自然科学一等奖(第二完成人);2020年获四川省青年科技奖;2021年获中国化学会青年手性化学奖

代表性成果 (获奖成果、专著、论文、专利)

1. Ziwei Zhong, Hongda Wu, Xiaofan Chen, Yao Luo, Longqing Yang, Xiaoming Feng,* Xiaohua Liu,* Visible-Light-Promoted Enantioselective Acylation and Alkylation of Aldimines Enabled by 9-Fluorenone Electron-Shuttle Catalysis, J. Am. Chem. Soc. 2024, 146, 20401−20413.

2. Liuzhen Hou, Longqing Yang, Gaofei Yang, Zhe Luo, Wanlong Xiao, Linhan Yang, Fei Wang, Liu-Zhu Gong, Xiaohua Liu,* Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Dearomative [2 + 2] Photocycloaddition/Ring-Expansion Sequence of Indoles with Diversified Alkenes, J. Am. Chem. Soc. 2024, 146, 23457–23466.

3. Nian Xu,† Maoping Pu,† Han Yu, Gaofei Yang, Xiaohua Liu,* Xiaoming Feng,* Iron-Catalyzed Asymmetric α-Alkylation of 2-Acylimidazoles via Dehydrogenative Radical Cross-Coupling with Alkanes, Angew. Chem. Int. Ed. 2024, 63, e202314256.

4. Yao Luo, Yuqiao Zhou, Fengnan Xiao, Xin He, Ziwei Zhong, Qi-Lin Zhou, Weidi Cao,* Xiaohua Liu,* Xiaoming Feng,* Quinone-Initiated Photocatalytic Enantioselective Giese Radical Addition with Ethers, Thioethers, Amines and Alkanes, ACS Catal. 2024, 14, 1203112041.

5. Tangyu Zhan, Liang Zhou, Yuqiao Zhou, Bingqian Yang, Xiaoming Feng,* Xiaohua Liu,* IronIII-Catalyzed Asymmetric Inverse-Electrondemand Hetero-Diels–Alder Reaction of Dioxopyrrolidines with Simple Olefins, Chem. Sci. 2024, 15, 4797−4803.

6. Yi Li,† Lichao Ning,† Qi Tang, Kexin Lan, Bingqian Yang, Qianchi Lin, Xiaoming Feng,* Xiaohua Liu,* Asymmetric Catalytic [1,3]- or [3,3]-Sigmatropic Rearrangement of 3-Allyloxy-4H-chromenones and Their Analogues, Chem. Sci. 2024, 15, 11005–11012.

7. Min Chen, Longqing Yang, Yuzhen Li, Yinhe Qu, Guihua Pan, Xiaoming Feng,* Xiaohua Liu,* Regioselective and Asymmetric Allylic Alkylation of Vinyl Epoxides for the Construction of Allylic Alcohols via Synergistic Catalysis, Sci. China Chem. 2024, 67, 542550.

8. Aying Yihuo, Maoping Pu, Zheng Tan, Jibang Liao, Jiuqi Tan, Qilin Zhou, Xiaohua Liu,* Xiaoming Feng,* Copper-Catalyzed Asymmetric Dearomatizing Amination of 2-Naphthols: C(sp2)-N Coupling via 1,3-Reductive Elimination, Sci. China Chem. 2024, 67, 2694–2700.

9. Qianping Chen, Yan Zhang, Yanji Song, Yang Zhang, Zhishan Su, Xiaoming Feng, Xiaohua Liu,* Asymmetric Synthesis of Hydroindoles via Desymmetrizing [3+2] Annulation of p‑Quinamines and Arylalkyl ketenes, Org. Lett. 2024, 26, 33663370.

10. Siyuan Wang, Lichao Ning, Zhiqiang Li, Xiaoming Feng*, Xiaohua Liu* Asymmetric Synthesis of Hydrodibenzofurans from Norcaradienes: Kinetic Resolutionvia [3 + 2] Cycloaddition with Quinones, Org. Lett. 2024, 26, 38443849.

11. Hongye Li, Yuqiao Zhou, Zheng Tan, Xiangyu Wang, Yuxin Zhang, Fei Wang, Xiaoming Feng,* Xiaohua Liu,* Enantioselective Sulfonylation to Construct 3-Sulfonylated Oxindoles, Chem. Commun. 2024, 60, 43544357.

12. Yongyan Zhang,† Lichao Ning,† Tianxin Zhu, Zheng Xie, Shunxi Dong, Xiaoming Feng Xiaohua Liu,* Chiral Guanidine Catalyzed Cyclization Reactions of 1,3-Enynes for Lactone Synthesis: Switchable H-bond Catalysis, Org. Chem. Front. 2024, 11, 28972904.

13. Dong Zhang, Maoping Pu, Zhenzhong Liu, Yuqiao Zhou, Zhendong Yang, Xiaohua Liu,* Yun-Dong Wu,* and Xiaoming Feng,* Enantioselective anti-Dihalogenation of Electron-Deficient Olefin: A Triplet Halo-Radical Pylon Intermediate, J. Am. Chem. Soc. 2023, 145, 48084818.

14. Qianwen He,† Mao-Ping Pu,† Zheng Jiang, Hongyu Wang, Xiaoming Feng,* Xiaohua Liu,* Asymmetric Epoxidation of Alkenes Catalyzed by a Cobalt Complex, J. Am. Chem. Soc. 2023, 145, 1561115618.

15. Guihua Pan, Maoping Pu, Hongyu Wang, Meijia Ying, Yi Li, Shunxi Dong, Xiaoming Feng, Xiaohua Liu,* Catalytic Enantioselective Nucleophilic Addition to Arynes by a New Quaternary Guanidinium Salt Based Phase-Transfer Catalyst, J. Am. Chem. Soc. 2023, 145, 26318−26327.

16. Kaixuan Wang, Longqing Yang, Yi Li, Hongye Li, Zhili Liu, Lichao Ning, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Catalytic Ring-Expansion of 3-Methyleneazetidines with α-Diazo Pyrazoamides towards Proline-Derivatives, Angew. Chem. Int. Ed. 2023, 62, e202307249.

17. Tangyu Zhan, Liangkun Yang, Qiyou Chen, Rui Weng, Xiaohua Liu,* Xiaoming Feng,* Chiral Lewis Acid-Catalyzed Norrish Type II Cyclization to Synthesize α-Oxazolidinones via Enantioselective Protonation, CCS Chem. 2023, 5, 2101–2110.

18. Shunxi Dong, Weidi Cao, Maoping Pu, Xiaohua Liu,* Xiaoming Feng,* Ligand-Acceleration in Chiral Lewis Acid Catalysis, CCS Chem. 2023, 5, 2717–2735.

19. Zhikun Wu, Xiying Zhang, Nian Xu, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Catalytic Aerobic Oxidative Radical Addition/Hydroxylation/1,4-Aryl Migration Reaction of Olefins, ACS Catal. 2023, 13, 815823.

20. Yuhao Mo, Qiyou Chen, Jinzhao Li, Dong Ye, Yuqiao Zhou, Shunxi Dong, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Catalytic Conjugate Addition of Cyanide to Chromones and βSubstituted Cyclohexenones, ACS Catal. 2023, 13, 877886.

21. Shiyang Li, Cefei Zhang, Guihua Pan, Liangkun Yang, Zhishan Su, Xiaoming Feng, Xiaohua Liu,* Enantioselective Photochemical Carbene Insertion into CC and CH Bonds of 1,3-Diketones by a Guanidine-Amide Organocatalyst, ACS Catal. 2023, 13, 46564666.

22. Xinyue Hu, Long Chen, Hongye Li, Qifan Xu, Xiaohua Liu,* Xiaoming Feng,* Enantioselective Catalytic Hantzsch Dihydropyridine Synthesis, ACS Catal. 2023, 13, 6675−6682.

23. Yongyan Zhang, Jin Wu, Lichao Ning, Qianping Chen, Xiaoming Feng, Xiaohua Liu,* Enantioselective Synthesis of Tetrasubstituted Allenes via Addition/Arylation Tandem Reaction of 2-Activated 1,3-Enynes, Sci. China Chem. 2023, 66, 526533.

24. Siyuan Wang, Yuqiao Zhou, Wanlong Xiao, Zegong Li, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Synthesis of Complex Tricyclo[3.2.2.0]nonenes from Racemic Norcaradienes: Kinetic Resolution via Diels–Alder Reaction, Chem. Sci. 2023, 14, 18441851.

25. Peiran Ruan, Cefei Zhang, Jin Wu, Fengnan Xiao, Yongyan Zhang, Qingfa Tan, Zhishan Su, Xiaoming Feng, Xiaohua Liu,* Asymmetric [3+2]-cyclization of a-Iminoamide Surrogates to Construct 3,4-Diaminopyrrolidine-2,5-diones, Chem. Commun. 2023, 59, 8250−8253.

26. Yanji Song, Shi Tang, Qianping Chen, Qingfa Tan, Weidi Cao, Xiaoming Feng, Xiaohua Liu,* Asymmetric Synthesis of Cyclopenta[b]indoles via Organocatalytic Formal (3 + 2) Cyclization of β-Ketoester with Azonaphthalene, Org. Chem. Front. 2023, 10, 2734–2739.

27. Changli He, Xiaoxue Tang, Xin He, Yuqiao Zhou, Xiaohua Liu,* Xiaoming Feng,* Regio- and Enantioselective Conjugate Addition of β-Nitro α,β-Unsaturated Carbonyls to Construct 3-Alkenyl Disubstituted Oxindoles, Chin. Chem. Lett. 2023, 34, 107487.

28. Wei Yang, Zhendong Yang, Long Chen, Yican Lu, Cefei Zhang, Zhishan Su, Xiaohua Liu,* Xiaoming Feng,* Chiral Nickel(II) Complex Catalyzed Asymmetric (3 + 2) Cycloaddition of α-Diazo Pyrazoleamides with 2-Siloxy-1-alkenes, Chin. Chem. Lett. 2023, 33, 107791.

29. Jianglin Qiao, Shiyu Wang, Xiaohua Liu,* Xiaoming Feng,* Enantioselective [3+2] Cycloaddition of Donor-Acceptor Aziridines and Imines to Construct 2,5-trans-Imidazolidines, Chem. Eur. J. 2023, 29, e202203757.

30. Qingfa Tan, Ning Guo, Linhan Yang, Fei Wang, Xiaoming Feng, and Xiaohua Liu,* Asymmetric Organocatalytic 1,6-Conjugate Addition of para-Quinone Methides Using [1,2]-Phospha-Brook Rearrangement, J. Org. Chem. 2023, 88, 9332−9342.

31. Zegong Li, Zi Zeng, Qi Tang, Ziwei Zhong, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Synthesis of 3-Lactone Substituted 2-Oxindoles with Vicinal Quaternary Carbon Centers via Vinylogous Conjugate Addition, Synlett 2023, 34, 2405−2410.

32. Weidi Cao, Xiaohua Liu,* Recent Advances on Catalytic Enantioselective Protonation for Construction of α-Tertiary Carbonyl Compounds, Chin. J. Org. Chem. 2023, 43, 961973.

33. Shunxi Dong, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Catalytic Rearrangements with αDiazocarbonyl Compounds, Acc. Chem. Res. 2022, 55, 415−428.

34. Xiaobin Lin,# Maoping Pu,# Xinpeng Sang, Shiyang Li, Xiaohua Liu,* Yun-Dong Wu,* Xiaoming Feng,* Asymmetric Catalytic (2+1) Cycloaddition of Thioketones to Synthesize Tetrasubstituted Thiiranes, Angew. Chem. Int. Ed. 2022, 61, e202201151.

35. Wanlong Xiao, Lichao Ning, Shuang Xin, Shunxi Dong, Xiaohua Liu,* XiaomingFeng,* Enantioselective [2+2] Cycloaddition of Allenyl Imidewith Mono-, or Disubstituted Alkenes, Angew. Chem. Int. Ed. 2022, 61, e202211596.

36. Lifeng Wang, Yuqiao Zhou, Zhishan Su, Fengcai Zhang, Weidi Cao, Xiaohua Liu,* Xiaoming Feng,* [3,3]-Sigmatropic Rearrangements of Naphthyl 1-Propargyl Ethers: para-Propargylation and Catalytic Asymmetric Dearomatization, Angew. Chem. Int. Ed. 2022, 61, e202211785.

37. Han Yu, Tangyu Zhan, Yuqiao Zhou, Long Chen, Xiaohua Liu,* Xiaoming Feng,* Visible-Light-Activated Asymmetric Addition of Hydrocarbons to Pyridine-Based Ketones, ACS Catal. 2022, 12, 5136−5144.

38. Yao Luo, Qi Wei, Liangkun Yang, Yuqiao Zhou, Weidi Cao, Zhishan Su, Xiaohua Liu,* Xiaoming Feng,* Enantioselective Radical Hydroacylation of α,β-Unsaturated Carbonyl Compounds with Aldehydes by Triplet Excited Anthraquinone, ACS Catal. 2022, 12, 1298412992.

39. Jiawen Lang, Siyuan Wang, Changli He, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Synthesis of Isochromanone Derivatives via Trapping Carboxylic Oxonium Ylides and Aldol Cascade, Chem. Sci. 2022, 13, 1163−1168.

40. Linfeng Hu, Jinzhao Li, Yongyan Zhang, Xiaoming Feng, Xiaohua Liu,* Enantioselective [1,2]-Stevens Rearrangement of Thiosulfonates to Construct Dithio-substituted Quaternary Carbon Centers, Chem. Sci. 2022, 13, 4103–4108.

41. Yi Li, Shuang Xin, Rui Weng, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Synthesis of Chromanone Lactones via Vinylogous Conjugate Addition of Butenolide to 2-Ester Chromones, Chem. Sci. 2022, 13, 8871–8875.

42. Peiran Ruan, Qiong Tang, Zun Yang, Xiaohua Liu,* Xiaoming Feng,* Enantioselective Formal [2+2+2] Cycloaddition of 1,3,5-Triazinanes to Construct Tetrahydropyrimidin-4-one Derivatives, Chem. Commun. 2022, 58, 1001−1004.

43. Chaoqi Ke, Qiuhui Cao, Yao Luo, Xiaohua Liu,* Xiaoming Feng,* Catalytic Asymmetric Amination of Azlactones with Azobenzenes, Chem. Commun. 2022, 58, 5881−5884.

44. Qingfa Tan, Qianping Chen, Zitong Zhu, Xiaohua Liu,* Asymmetric Organocatalytic Sulfenylation for the Construction of a Diheteroatom-bearing Tetrasubstituted Carbon Centre, Chem. Commun. 2022, 58, 9686–9689.

45. Yi Li, Wang-Yuren Li, Xiaoxue Tang, Xiaohua Liu,* Xiaoming Feng,* Synthesis of Chiral Pyridine-oxazolines via Catalytic Asymmetric Heine Reaction of meso-N-(2-picolinoyl)-aziridines, Org. Chem. Front. 2022, 9, 1531−1535.

46. Jinzhao Li, Lichao Ning, Qingfa Tan, Xiaoming Feng, Xiaohua Liu,* Asymmetric Sonogashira C(sp3 )-C(sp) Bond Coupling Enabled by Copper(I) Complex of New Guanidine-hybrid Ligand, Org. Chem. Front. 2022, 9, 6312−6318.

47. Fei Tan,# Maoping Pu,# Jun He, Jinzhao Li, Jian Yang, Shunxi Dong, Xiaohua Liu,* Yun-Dong Wu,* Xiaoming Feng,* Catalytic Asymmetric Homologation of Ketones with α-Alkyl-α-diazoesters, J. Am. Chem. Soc. 2021, 143, 2394−2402.

48. Wei Yang,# Maoping Pu,# Xiaobin Lin, Min Chen, Yanji Song, Xiaohua Liu,* Yun-Dong Wu,* Xiaoming Feng,* Enantioselective Formal Vinylogous N−H Insertion of Secondary Aliphatic Amines Catalyzed by a High-Spin Cobalt(II) Complex, J. Am. Chem. Soc. 2021, 143, 9648−9656.

49. Wen Liu,# Maoping Pu,# Jun He, Tinghui Zhang, Shunxi Dong, Xiaohua Liu,* Yun-Dong Wu,* Xiaoming Feng,* Iron-Catalyzed Enantioselective Radical Carboazidation and Diazidation of , a,b-Unsaturated Carbonyl Compounds, J. Am. Chem. Soc. 2021, 143, 11856−11863.

50. Long Chen,# Maoping Pu,# Shiyang Li, Xinpeng Sang, Xiaohua Liu,* Yun-Dong Wu,* and Xiaoming Feng,* Enantioselective Synthesis of Nitriles Containing a Quaternary Carbon Center by Michael Reactions of Silyl Ketene Imines with 1‑Acrylpyrazoles, J. Am. Chem. Soc. 2021, 143, 19091–19098.

51. Yong Xia, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Catalytic Reactions of Donor-Acceptor Cyclopropanes, Angew. Chem. Int. Ed. 2021, 60, 9192–9204.

52. Jinzhao Li, Yuhao Mo, Liqiao Yan, Xiaoming Feng, Zhishan Su,* Xiaohua Liu,* Organocatalytic Stereoselective [8+2] Cycloaddition of Tropones with Azlactones, CCS Chem. 2021, 3, 784–793.

53. Xia Zhong, Ziwei Zhong, Zhikun Wu, Zhen Ye, Yuxiang Feng, Shunxi Dong, Xiaohua Liu,* Qian Peng,* Xiaoming Feng,* Chiral Lewis Acid-bonded Picolinaldehyde Enables Enantiodivergent Carbonyl Catalysis in Mannich/Condensation Reaction of Glycine Ester, Chem. Sci. 2021, 12, 43534360.

54. Lihua Xie, Yi Li, Shunxi Dong, Xiaoming Feng, Xiaohua Liu,* Catalytic Asymmetric Formal [3+2] Cycloaddition of Isatogens with Azlactones to Construct Indolin-3-one Derivatives, Chem. Commun., 2021, 57, 239−242.

55. Qingfa Tan, Han Yu, Yao Luo, Fenzhen Chang, Xiaohua Liu,* Yuqiao Zhou,* Xiaoming Feng,* Asymmetric Catalytic [4+3] Cycloaddition of ortho-Quinone Methides with Oxirances, Chem. Commun., 2021, 57, 3018−3021.

56. Linfeng Hu, Weidi Cao, Kaixuan Wang, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Synthesis of Dihydrocarbazoles through Friedel-Crafts Alkylation/annulation Sequential Reaction of Indoles, Chem. Commun., 2021, 57, 13138−13141.

57. Jian Xu, Runze Li, Nian Xu, Xiaohua Liu,* Fei Wang,* Xiaoming Feng,* Enantioselective [4 + 2] Cycloaddition/Cyclization Cascade Reaction and Total Synthesis of cis-Bis(cyclotryptamine) Alkaloids, Org. Lett. 2021, 23, 1856−1861.

58. Qianwen He, Dong Zhang, Fengcai Zhang, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Catalytic Epoxidation of Terminal Enones for the Synthesis of Triazole Antifungal Agents, Org. Lett. 2021, 23, 6961−6966.

59. Wenkun Yang, Pei Dong, Jian Xu, Jian Yang, Xiaohua Liu,* Xiaoming Feng,* Enantioselective synthesis of 3-substituted 3-amino-2-oxindoles via amination with anilines, Chem. Eur. J. 2021, 27, 92729275.

60. Chaoqi Ke, Zhenzhong Liu, Sai Ruan, Xiaoming Feng, Xiaohua Liu,* Organocatalytic Asymmetric Synthesis of Benzothiazolopyrimidines via a [4 + 2] Cycloaddition of Azlactones with 2-Benzothiazolimines, Org. Chem. Front. 2021, 8, 5705−5709.

61. Peng Zhao, Zegong Li, Jun He, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Catalytic 1,3-Dipolar Cycloaddition of α-Diazoesters for Synthesis of 1-Pyrazoline-based Spirochromanones and Beyond, Sci. China Chem. 2021, 64, 1355−1360.

62. Peng Zhao, Zi Zeng, Xiaoming Feng,* Xiaohua Liu,* Multisubstituted Pyrazole Synthesis via [3+2] Cycloaddition/Rearrangement/N-H Insertion Cascade Reaction of α-Diazoesters and Ynones, Chin. Chem. Lett. 2021, 32, 132−135.

63. Yi Li, Hao Pan, Wangyuren Li, Xiaoming Feng, Xiaohua Liu,* Enantioselective Nucleophilic Aromatic Substitution Reaction of Azlactones to Synthesize Quaternary α-Amino Acid Derivatives, Synlett 2021, 32, 587−592.

64. Weidi Cao, Xiaohua Liu,* Asymmetric Formal Hetero-Ene Reaction of Allylgold Intermediates, Chin. J. Org. Chem. 2021, 41, 857−858.

65. Dong Zhang, Zhisan Su, Qianwen He, Zhikun Wu, Yuqiao Zhou, Chenjing Pan, Xiaohua Liu,* Xiaoming Feng,* Diversified Transformations of Tetrahydroindolizines to Construct Chiral 3-Arylindolizines and Dicarbofunctionalized 1,5-Diketones, J. Am. Chem. Soc. 2020, 142, 15975−15985.

66. Xiying Zhang, Wangbin Wu, Weidi Cao, Han Yu, Xi Xu, Xiaohua Liu,* Xiaoming Feng,* Enantioselective Radical-Polar Crossover Reactions of Indanonecarboxamides with Alkenes, Angew. Chem. Int. Ed. 2020, 59, 4846−4850.

67. Tengfei Kang, Liuzhen Hou, Sai Ruan, Weidi Cao, Xiaohua Liu,* Xiaoming Feng,* Lewis acid-catalyzed asymmetric reactions of β,γ-unsaturated 2-acyl imidazoles, Nat. Commun. 2020, 11, 3869.

68. Xiaobin Lin, Zheng Tan, Wenkun Yang, Wei Yang, Xiaohua Liu,* Xiaoming Feng,* Chiral Cobalt(ΙΙ) Complex Catalyzed Asymmetric [2,3]-Sigmatropic Rearrangement of Allylic Selenides with α-Diazo Pyrazoleamides, CCS Chem. 2020, 2, 1423–1433.

69. Jian Xu, Ziwei Zhong, Mingyi Jiang, Yuqiao Zhou, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Catalytic Concise Synthesis of Hetero-3,3ʹ-Bisoxindoles for the Construction of Bispyrroloindoline Alkaloids, CCS Chem. 2020, 2, 1894–1902.

70. Zhen Wang, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Catalysis Enabled by Chiral N,N'-Dioxide–Nickel(II) Complexes, Aldrichimica ACTA, 2020, 53, 3−10.

71. Qianchi Lin, Bowen Hu, Xi Xu, Shunxi Dong, Xiaohua Liu,* Xiaoming Feng,* Chiral N,Nʹ-Dioxide/Mg(OTf)2 Complex-Catalyzed Asymmetric [2,3]-Rearrangement of in situ Generated Ammonium Salts, Chem. Sci. 2020, 11, 3068−3073.

72. Bin Shen, Qianwen He, Shunxi Dong, Xiaohua Liu,* Xiaoming Feng,* Chiral Cobalt(II) Complex Catalyzed Enantioselective Aza-Piancatelli Rearrangement/Diels-Alder Cascade Reaction, Chem. Sci. 2020, 11, 3862−3867.

73. Lifeng Wang, Pengfei Zhou, Qianchi Lin, Shunxi Dong, Xiaohua Liu,* Xiaoming Feng,* Chiral Fe(II) Complex Catalyzed Enantioselective [1,3] O-to-C Rearrangement of Alkyl Vinyl Ethers and Synthesis of Chromanols and Beyond, Chem. Sci. 2020, 11, 10101−10106.

74. Sai Ruan, Xia Zhong, Quangang Chen, Xiaoming Feng, Xiaohua Liu,* An Asymmetric Hydrocyanation/Michael reaction of a-Diazoacetates via Cu(I)/Chiral Guanidine Catalysis, Chem. Commun. 2020, 56, 2155−2158.

75. Wei Yang, Xiaobin Lin, Yongyan Zhang, Weidi Cao, Xiaohua Liu,* Xiaoming Feng,* Nickel(II)-catalyzed asymmetric thio-Claisen rearrangement of α-diazo pyrazoleamides with thioindoles, Chem. Commun. 2020, 56, 10002−10005.

76. Dong Zhang, Shunxi Dong, Qianwen He, Yao Luo, Yun Liu, Xiaohua Liu,* Xiaoming Feng,* Enantioselective Dicarbofunctionalization of (E)-Alkenyloxindoles with Pyridinium Salts by Chiral Lewis Acid/Photo Relay Catalysis, Chem. Commun. 2020, 56, 12757−12760.

77. Haipeng Hu, Jinxiu Xu, Fang Wang, Shunxi Dong, Xiaohua Liu,* Xiaoming Feng,* Chiral ScIII-N,N′‑Dioxide-Catalyzed 1,3-Dipolar Cycloaddition of Diaziridines with Chalcones, Org. Lett. 2020, 22, 93−97.

78. Xi Xu, Shunxi Dong, LiLi Feng, Sijing Wang, Xiaohua Liu,* Xiaoming Feng,* Kinetic Resolution of Propargylic Ethers via [2,3]-Wittig Rearrangement to Synthesize Chiral α‑Hydroxyallenes, Org. Lett. 2020, 22, 2692−2696.

79. Hang Zhang, Yao Luo, Chenhao Zhu, Shunxi Dong, Xiaohua Liu,* Xiaoming Feng,* Catalytic Asymmetric Addition Reactions of Formaldehyde N,Nʹ‑Dialkylhydrazone to Synthesize Chiral Nitrile Derivatives, Org. Lett. 2020, 22, 5217−5222.

80. Xiaobin Lin, Wei Yang, Wenkun Yang, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Catalytic [2,3] Stevens and Sommelet–Hauser Rearrangements of a-Diazo Pyrazoleamides with Sulfides, Angew. Chem. Int. Ed. 2019, 58, 13492–13498.

81. Qian Xiong, Shunxi Dong, Yushuang Chen, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Synthesis of Tetrazole and Dihydroisoquinoline Derivatives by Isocyanidebased Multicomponent Reactions, Nat. Commun. 2019, 10, 2116.

82. Yu Zhang, Fengcai Zhang, Long Chen, Jian Xu, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Synthesis of P-Stereogenic Compounds via Thulium(III)-Catalyzed Desymmetrization of Dialkynylphosphine Oxides, ACS Catal. 2019, 9, 4834−4840.

83. Wangbin Wu, Weidi Cao, Linfeng Hu, Zhishan Su, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Baeyer–Villiger Oxidation: Classical and Parallel Kinetic Resolution of 3-Substituted Cyclohexanones and Desymmetrization of meso-Disubstituted Cycloketones, Chem. Sci. 2019, 10, 7003−7008.

84. Jian Yang, Peiran Ruan, Wei Yang, Xiaoming Feng, Xiaohua Liu,* Enantioselective carbene insertion into the N–H bond of benzophenone imine, Chem. Sci. 2019, 10, 10305−10309.

85. Lihua Xie, Shunxi Dong, Qian Zhang, Xiaoming Feng, Xiaohua Liu,* Asymmetric Construction of Dihydrobenzofuran-2,5-dione Derivatives via Desymmetrization of p-Quinols with Azlactones, Chem. Commun. 2019, 55, 87−90.

86. Pengfei Zhou, Xiaohua Liu,* Wangbin Wu, Chaoran Xu, Xiaoming Feng,* Catalytic Asymmetric Construction of β‑Azido Amides and Esters via Haloazidation, Org. Lett. 2019, 21, 1170−1175.

87. Hang Zhang, Yao Luo, Dawei Li, Qian Yao, Shunxi Dong, Xiaohua Liu,* Xiaoming Feng,* Enantioselective Synthesis of 4-Hydroxy-dihydrocoumarins via Catalytic Ring Opening/Cycloaddition of Cyclobutenones, Org. Lett. 2019, 21, 2388–2392.

88. Jiawen Lang, Yi Li, Tengfei Kang, Xiaoming Feng, Xiaohua Liu,* Organocatalytic Asymmetric Michael/Dieckmann Cyclization Reaction of Alkynones To Construct Spirocyclopentene Oxindoles, Org. Lett. 2019, 21, 6897−6902.

89. Weidi Cao, Xiaoming Feng, Xiaohua Liu,* Reversal of enantioselectivity in chiral metal complex-catalyzed asymmetric reactions, Org. Biomol. Chem. 2019, 17, 6538−6550.

90. Shunxi Dong, Xiaoming Feng, Xiaohua Liu,* Chiral Guanidines and Their Derivatives in Asymmetric Synthesis, Chem. Soc. Rev. 2018, 47, 8525–8540.

91. Xiaobin Lin, Yu Tang, Wei Yang, Fei Tan, Lili Lin, Xiaohua Liu,* Xiaoming Feng,* Chiral Nickel(II) Complex Catalyzed Enantioselective Doyle-Kirmse Reaction of α-Diazo Pyrazoleamides, J. Am. Chem. Soc. 2018, 140, 3299–3305.

92. Yu Tang, Jian Xu, Jian Yang, Lili Lin, Xiaoming Feng, and Xiaohua Liu,* Asymmetric Three-Component Reaction for the Synthesis of Tetrasubstituted Allenoates via Allenoate-Copper Intermediates, Chem. 2018, 4, 16581672.

93. Haifeng Zheng, Yan Wang, Chaoran Xu, Xi Xu, Lili Lin, Xiaohua Liu,* Xiaoming Feng,* Stereodivergent Synthesis of Vicinal Quaternary-quaternary Stereocenters and Bioactive Hyperolactones, Nat. Commun. 2018, 1968−1974.

94. Yuhang Zhou, Lili Lin, Xiaohua Liu,* Xinyue Hu, Yan Lu, Xiying Zhang, Xiaoming Feng,* Catalytic Asymmetric Diels-Alder Reaction/[3,3] Sigmatropic Rearrangement Cascade of 1-Thiocyanatobutadienes, Angew. Chem. Int. Ed. 2018, 57, 9113–9116.

95. Fei Tan, Xiaohua Liu,* Yan Wang, Shunxi Dong, Han Yu, Xiaoming Feng,* Chiral Lewis Acid Catalyzed Reactions of a-Diazoester Derivatives: Construction of Dimeric Polycyclic Compounds, Angew. Chem. Int. Ed. 2018, 57, 16176–16179.

96. Xiaohua Liu, Xiaoming Feng,* Dual Nickel and Br➢nsted Acid Catalysis for Hydroalkenylation, Angew. Chem. Int. Ed. 2018, 57, 16604–16605.

97. Songsong Guo, Pei Dong, Yushuang Chen, Xiaoming Feng, Xiaohua Liu,* Chiral Guanidine/Copper Catalyzed Asymmetric Azide-Alkyne Cycloaddition/[2+2] Cascade Reaction, Angew. Chem. Int. Ed. 2018, 57, 16852–16856.

98. Yulong Kuang, Bin Shen, Li Dai, Qian Yao, Xiaohua Liu,* Lili Lin, Xiaoming Feng,* Diastereodivergent Asymmetric Michael-Alkylationreactions Using Chiral N,N′-Dioxide/Metal Complexes, Chem. Sci. 2018, 9, 688–692.

99. Quangang Chen, Lihua Xie, Zhaojing Li, Yu Tang, Peng Zhao, Lili Lin, Xiaoming Feng and Xiaohua Liu,* Copper/Guanidine-catalyzed Asymmetric Alkynylation of Isatin-Derived Ketimines, Chem. Commun. 2018, 54, 678−681.

100. Peng Zhao, Simeng Wu, Chaoqi Ke, Xiaohua Liu,* Xiaoming Feng,* Chiral Lewis Acid-Catalyzed Enantioselective Cyclopropanation and C–H Insertion Reactions of Vinyl Ketones with α-Diazoesters, Chem. Commun. 2018, 54, 9837–9840.

101. Jing Guo, Xiaohua Liu,* Changqiang He, Fei Tan, Shunxi Dong and Xiaoming Feng,* Nickel(II)-catalyzed Enantioselective α-Alkylation of b-Ketoamides with Phenyliodonium Ylide via a Radical Process, Chem. Commun. 2018, 54, 12254–12257.

102. Jian Yang, Chaoqi Ke, Dong Zhang, Xiaohua Liu,* Xiaoming Feng,* Enantioselective Synthesis of 2,2,3-Trisubstituted Indolines via Bimetallic Relay Catalysis of α-Diazoketones with Enones, Org. Lett. 2018, 20, 4536–4539.

103. Li Dai, Lili Lin, Jianfeng Zheng, Dong Zhang, Xiaohua Liu,* Xiaoming Feng,* N,N′-Dioxide/Gd(OTf)3 Complex-Promoted Asymmetric Aldol Reaction of Silyl Ketene Imines with Isatins: Water Plays an Important Role, Org. Lett. 2018, 20, 53148–5318.

104. Tengfei Kang, Peng Zhao, Jian Yang, Lili Lin, Xiaoming Feng, and Xiaohua Liu,* Asymmetric Catalytic Double Michael Additions for the Synthesis of Spirooxindoles, Chem. Eur. J. 2018, 24, 3703−3706.

105. Jianlin Zhang, Wanlong Xiao, Haipeng Hu, Lili Lin, Xiaohua Liu,* Xiaoming Feng,* Catalytic Asymmetric [8+3] Annulation Reactions of Tropones or Azaheptafulvenes with meso-Aziridines, Chem. Eur. J., 2018, 24, 13428–13431.

106. Han Yu, Shunxi Dong, Qian Yao, Long Chen, Dong Zhang, Xiaohua Liu,* Xiaoming Feng,* N,N¢-Dioxide-Metal Complexes Mediated Enantioselective [2+2] Photocycloadditions of Enones and Olefins with Visible Light, Chem. Eur. J. 2018, 24, 19361–19367.

107. Sai Ruan, Xiaobin Lin, Lihua Xie, Lili Lin, Xiaoming Feng and Xiaohua Liu,* Asymmetric Synthesis of 3-Aminodihydrocoumarins via the Chiral Guanidine Catalyzed Cascade Reaction of Azlactones, Org. Chem. Front. 2018, 5, 32–35.

108. Yong Xia, Fenzhen Chang, Lili Lin, Yali Xu, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Ring-Opening of Cyclopropyl Ketones with β-Naphthols Catalyzed by a Chiral N,N′-Dioxide-Scandium(III) Complex, Org. Chem. Front. 2018, 5, 1293–1296.

109. Jianlin Zhang, Xiaohua Liu,* Songsong Guo, Changqiang He, Wanlong Xiao, Lili Lin, Xiaoming Feng,* Enantioselective Formal [4 + 2] Annulation of ortho-Quinone Methides with ortho-Hydroxyphenyl α,β-Unsaturated Compounds, J. Org. Chem. 2018, 83, 10175–10185.

110. Xiaohua Liu, Shunxi Dong, Lili Lin, Xiaoming Feng,* Chiral Amino Acids-Derived Catalysts and Ligands, Chin. J. Chem. 2018, 36, 791–797.

111. Weidi Cao, Xiaohua Liu,* Xiaoming Feng, Chiral Organobases: Properties and Applications in Asymmetric Catalysis, Chin. Chem. Lett. 2018, 29, 1201−1208.

112. Xiaohua Liu, Haifeng Zheng, Yong Xia, Lili Lin, and Xiaoming Feng,* Asymmetric Cycloaddition and Cyclization Reactions Catalyzed by Chiral N,N¢-Dioxide−Metal Complexes, Acc. Chem. Res. 2017, 50, 2621−2631

113. Jianfeng Zheng, Lili Lin, Li Dai, Qiong Tang, Xiaohua Liu,* and Xiaoming Feng,* Nickel-Catalyzed Conjugate Addition of Silyl Ketene Imines to In Situ Generated Indol-2-ones: Highly Enantioselective Construction of Vicinal All-Carbon Quaternary Stereocenters, Angew. Chem. Int. Ed. 2017, 56, 13107–13111.

114. Jun Li, Lili Lin, Bowen Hu, Pengfei Zhou, Tianyu Huang, Xiaohua Liu,* and Xiaoming Feng,* Gold(I)/Chiral N,N¢-Dioxide–Nickel(II) Relay Catalysis for Asymmetric Tandem Intermolecular Hydroalkoxylation/Claisen Rearrangement, Angew. Chem. Int. Ed. 2017, 56, 885–888.

115. Tianyu Huang, Xiaohua Liu,* Jiawen Lang, Jian Xu, Lili Lin, and Xiaoming Feng,* Asymmetric Aerobic Oxidative Cross-Coupling of Tetrahydroisoquinolines with Alkynes, ACS Catal. 2017, 7, 5654−5660.

116. Yuting Liao, Baixin Zhou, Yong Xia, Xiaohua Liu,* Lili Lin, and Xiaoming Feng,* Asymmetric [3 + 2] Cycloaddition of 2,2′-Diester Aziridines To Synthesize Pyrrolidine Derivatives, ACS Catal. 2017, 7, 3934−3939.

117. Yu Zhang, Yuting Liao, Xiaohua Liu,* Xi Xu, Lili Lin and Xiaoming Feng,* Catalytic Asymmetric Hydroxylative Dearomatization of 2-Naphthols: Synthesis of Lacinilene Derivatives, Chem. Sci., 2017, 8, 6645−6649.

118. Weiwei Luo, Lili Lin, Yu Zhang, Xiaohua Liu,* and Xiaoming Feng,* Construction of Distant Stereocenters by Enantioselective Desymmetrizing Carbonyl-Ene Reaction, Org. Lett. 2017, 19, 3374−3377.

119. Qian Zhang, Songsong Guo, Jian Yang, Kunru Yu, Xiaoming Feng, Lili Lin, and Xiaohua Liu,* Asymmetric Formal [3 + 2]-Cycloaddition of Azomethine Imines with Azlactones To Synthesize Bicyclic Pyrazolidinones, Org. Lett. 2017, 19, 5826−5829.

120. Baiwei Ma, Weiwei Luo, Lili Lin, Xiaohua Liu* and Xiaoming Feng,* A Chiral Cobalt(II) Complex Catalyzed Asymmetric Formal [3+2] Cycloaddition for the Synthesis of 1,2,4-Triazolines, Chem. Commun. 2017, 53, 4077−4079.

121. Chaoran Xu, Haifeng Zheng, Bowen Hu, Xiaohua Liu,* Lili Lin and Xiaoming Feng,* Chiral Cobalt(II) Complex Catalyzed Friedel–Crafts Aromatization for the Synthesis of Axially Chiral Biaryldiols, Chem. Commun. 2017, 53, 9741−9744.

122. Guojin Wang, Yu Tang, Yu Zhang, Xiaohua Liu,* Lili Lin, and Xiaoming Feng,* Enantioselective Synthesis of N-H-Free 1,5-Benzothiazepines, Chem. Eur. J. 2017, 23, 554–557.

123. Baiwei Ma, Xiaobin Lin, Lili Lin, Xiaoming Feng,* and Xiaohua Liu,* Chiral N,N¢‑Dioxide Organocatalyzed Asymmetric Electrophilic α‑Cyanation of β‑Keto Esters and β‑Keto Amides, J. Org. Chem. 2017, 82, 701−708.

124. Yushuang Chen, Xiaohua Liu,* Weiwei Luo, Lili Lin, Xiaoming Feng, Asymmetric Organocatalytic Michael/Michael/Henry Sequence to Construct Cyclohexanes with Six Vicinal Stereogenic Centers, Synlett, 2017, 28, 966–969.

125. Yong Xia, Lili Lin, Fenzhen Chang, Yuting Liao, Xiaohua Liu,* and Xiaoming Feng,* Asymmetric Ring Opening/Cyclization/Retro-Mannich Reaction of Cyclopropyl Ketones with Aryl 1,2-Diamines for the Synthesis of Benzimidazole Derivatives, Angew. Chem. Int. Ed. 2016, 55, 12228–12232.

126. Haipeng Hu, Yangbin Liu, Lili Lin, Yuheng Zhang, Xiaohua Liu,* and Xiaoming Feng*, Kinetic Resolution of 2H-Azirines by Asymmetric Imine Amidation, Angew. Chem. Int. Ed. 2016, 55, 10098–10101.

127. Qian Yao, Yuting Liao, Lili Lin, Xiaobin Lin, Jie Ji, Xiaohua Liu,* and Xiaoming Feng,* Efficient Synthesis of Chiral Trisubstituted 1,2-Allenyl Ketones by Catalytic Asymmetric Conjugate Addition of Malonic Esters to Enynes, Angew. Chem. Int. Ed. 2016, 55, 1859–1863.

128. Yangbin Liu, Xiaohua Liu,* Haipeng Hu, Jing Guo, Yong Xia, Lili Lin, and Xiaoming Feng,* Synergistic Kinetic Resolution and Asymmetric Propargyl Claisen Rearrangement for the Synthesis of Chiral Allenes, Angew. Chem. Int. Ed. 2016, 55, 4054–4058.

129. Quangang Chen, Yu Tang, Tianyu Huang, Xiaohua Liu,* Lili Lin, and Xiaoming Feng, Copper/Guanidine-Catalyzed Asymmetric Alkynylation of Isatins, Angew. Chem. Int. Ed. 2016, 55, 5286–5289.

130. Tengfei Kang, Shulin Ge, Lili Lin, Yan Lu, Xiaohua Liu,* and Xiaoming Feng,* A Chiral N,N-Dioxide–ZnII Complex Catalyzes the Enantioselective [2+2] Cycloaddition of Alkynones with Cyclic Enol Silyl Ethers, Angew. Chem. Int. Ed. 2016, 55, 5541–5544.

131. Jun Li, Lili Lin, Bowen Hu, Xiangjin Lian, Gang Wang, Xiaohua Liu,* and Xiaoming Feng,* Bimetallic Gold(I)/Chiral N,N-Dioxide Nickel(II) Asymmetric Relay Catalysis: Chemo- and Enantioselective Synthesis of Spiroketals and Spiroaminals, Angew. Chem. Int. Ed. 2016, 55, 6075–6078.

132. Fei Tan, Xiaohua Liu,* Xiaoyu Hao, Yu Tang, Lili Lin, and Xiaoming Feng, Asymmetric Catalytic Insertion of α-Diazo Carbonyl Compounds into O−H Bonds of Carboxylic Acids, ACS Catal. 2016, 6, 6930−6934.

133. Gang Wang, Xiaohua Liu,* Yushuang Chen, Jian Yang, Jun Li, Lili Lin, and Xiaoming Feng,* Diastereoselective and Enantioselective Alleno-aldol Reaction of Allenoates with Isatins to Synthesis of Carbinol Allenoates Catalyzed by Gold, ACS Catal. 2016, 6, 2482−2486.

134. Jing Guo, Yangbin Liu, Xiangqiang Li, Xiaohua Liu,* Lili Lin and Xiaoming Feng,* Nickel(II)-Catalyzed Enantioselective Cyclopropanation of 3-Alkenyl-oxindoles with Phenyliodonium Ylide via Free Carbine, Chem. Sci. 2016, 7, 2717–2721.

135. Yuting Liao, Xiaohua Liu,* Yu Zhang, Yali Xu, Yong Xia, Lili Lin and Xiaoming Feng,* Asymmetric [3 + 2] Cycloaddition of Donor–Acceptor Aziridines with Aldehydes via Carbon–Carbon Bond Cleavage, Chem. Sci. 2016, 7, 3775–3779.

136. Weiwei Luo, Xiao Yuan, Lili Lin, Pengfei Zhou, Xiaohua Liu* and Xiaoming Feng,* A N,N′-Dioxide/Mg(OTf)2 Complex Catalyzed Enantioselective α-Addition of Isocyanides to Alkylidene Malonates, Chem. Sci. 2016, 7, 4736–4740.

137. Jing Guo, Lili Lin, Yangbin Liu, Xiangqiang Li, Xiaohua Liu,* and Xiaoming Feng,* Nickel(II)-Catalyzed Enantioselective α-Vinylation of β-Keto Amides/Esters with Hypervalent Iodine Salts, Org. Lett. 2016, 18, 5540−5543.

138. Xiaobin Lin, Sai Ruan, Qian Yao, Chengkai Yin, Lili Lin, Xiaoming Feng, and Xiaohua Liu,* Kinetic Resolution of Oxaziridines via Chiral Bifunctional Guanidine-Catalyzed Enantioselective α-Hydroxylation of β-Keto Esters, Org. Lett. 2016, 18, 3602−3605.

139. Songsong Guo, Xiaohua Liu,* Bin Shen, Lili Lin, and Xiaoming Feng, Organocatalytic Asymmetric Cascade Reaction of 2-Hydroxyphenyl-Substituted Enones and Isocyanates To Construct 1,3-Benzoxazin-2-ones, Org. Lett. 2016, 18, 5070–5073.

140. Yangbin Liu, Haipeng Hu, Lili Lin, Xiaoyu Hao, Xiaohua Liu* and Xiaoming Feng,* Enantioselective Construction of Branched 1,3-Dienyl Substituted Quaternary Carbon Stereocenters by Asymmetric Allenyl Claisen Rearrangement, Chem. Commun. 2016, 52, 11963–11966.

141. Yu Zhang, Yuting Liao, Xiaohua Liu,* Qian Yao, Yuhang Zhou, Lili Lin, and Xiaoming Feng,* Catalytic Michael/Ring-Closure Reaction of α,β-Unsaturated Pyrazoleamides with Amidomalonates: Asymmetric Synthesis of (-)-Paroxetine, Chem. Eur. J. 2016, 22, 15119–15124.

142. Yong Xia, Lili Lin, Fenzhen Chang, Xuan Fu, Xiaohua Liu*, Xiaoming Feng,* Asymmetric Ring-Opening of Cyclopropyl Ketones with Thiol, Alcohol, and Carboxylic Acid Nucleophiles Catalyzed by a Chiral N,N′-Dioxide–Scandium(III) Complex, Angew. Chem. Int. Ed. 2015, 54, 13748–13752.

143. Haifeng Zheng, Xiaohua Liu,* Chaoran Xu, Yong Xia, Lili Lin, Xiaoming Feng,* Regio- and Enantioselective Aza-Diels–Alder Reactions of 3-Vinylindoles: A Concise Synthesis of the Antimalarial Spiroindolone NITD609, Angew. Chem. Int. Ed., 2015, 54, 10958−10962.

144. Yu Tang, Quangang Chen, Xiaohua Liu,* Gang Wang, Lili Lin, and Xiaoming Feng, Direct Synthesis of Chiral Allenoates from the Asymmetric C-H Insertion of α-Diazoesters into Terminal Alkynes, Angew. Chem. Int. Ed., 2015, 54, 9512−9516.

145. Xiaohu Zhao, Xiaohua Liu,* Hongjiang Mei, Jing Guo, Lili Lin, Xiaoming Feng,* Asymmetric Dearomatization of Indoles through Michael/Friedel–Crafts-Type Cascade to Construct Polycyclic Spiroindolines, Angew. Chem. Int. Ed. 2015, 54, 40324035.

146. Yong Xia, Xiaohua Liu,* Haifeng Zheng, Lili Lin, Xiaoming Feng,* Asymmetric Synthesis of 2,3-Dihydropyrroles by Ring-Opening/Cyclization of Cyclopropyl Ketones Using Primary Amines, Angew. Chem. Int. Ed. 2015, 54, 227230.

147. Kunru Yu, Xiaohua Liu,* Xiaobin Lin, Lili Lin and Xiaoming Feng, Organocatalytic Dynamic Kinetic Resolution of Azlactones to Construct Chiral N-Acyl Amino Acid Oxime Esters; Chem. Commun., 2015, 51, 14897−14900.

148. Bing Fang, Xiaohua Liu,* Jiannan Zhao, Yu Tang, Lili Lin, Xiaoming Feng,* Chiral Bifunctional Guanidine-Catalyzed Enantioselective Aza-Henry Reaction of Isatin-Derived Ketimines, J. Org. Chem. 2015, 80, 3332−3338

149. Yan Lu, Min, Wang, Xiaohu Zhao, Xiaohua Liu,* Lili Lin, Xiaoming Feng*, Reaction of Isatin-Derived Ketimines Iso- Reaction of Isatin-Derived Ketimines, Synlett 2015, 26, 1545−1548.

150. Yin Zhu, Xiaohua Liu,* Shunxi Dong, Yuhang Zhou, Wei Li, Lili Lin, and Xiaoming Feng,* Asymmetric N-H Insertion of Secondary and Primary Anilines under the Catalysis of Palladium and Chiral Guanidine Derivatives, Angew. Chem. Int. Ed. 2014, 53, 1636–1640.

151. Xiaohua Liu, Lili Lin and Xiaoming Feng,* Chiral N,N¢-Dioxide Ligands: Synthesis, Coordination Chemistry and Asymmetric Catalysis, Org. Chem. Front. 2014, 1, 298–302.

152. Zuliang Zhang, Xiaohua Liu,* Zhen Wang, Xiaohu Zhao, Lili Lin, Xiaoming Feng,* Chiral Co(II) Complex Catalyzed Asymmetric Michael Reactions of β-Ketoamides to Nitroolefins and Alkynones, Tetrahedron Lett. 2014, 55, 3797−3801.

153. Xiaohua Liu, Ke Zheng, Xiaoming Feng,* Advancements in Catalytic Asymmetric Intermolecular Ene-Type Reactions, Synthesis 2014; 46, 2241−2257.

154. Shunxi Dong, Xiaohua Liu,* Yin Zhu, Peng He, Lili Lin, Xiaoming Feng,* Organocatalytic Oxyamination of Azlactones: Kinetic Resolution of Oxaziridines and Asymmetric Synthesis of Oxazolin-4-ones, J. Am. Chem. Soc. 2013, 135, 10026‒10029.

155. Min Wang, Xiaohua Liu,* Peng He, Lili Lin, Xiaoming Feng,* Enantioselective Synthesis of 1,2,4-Triazolines by Chiral Iron(II)-Complex Catalyzed Cyclization of α-Isocyano Esters and Azodicarboxylates, Chem. Commun. 2013, 49, 2572–2574.

156. Jingjing Yao, Xiaohua Liu*, Peng He, Yin Zhu, Xiangjin Lian, Lili Lin, Xiaoming Feng,* Chiral-Zn(NTf2)2-Complex-Catalyzed Diastereo- and Enantioselective Direct Conjugate Addition of Arylacetonitriles to Alkylidene Malonates, Chem. Eur. J. 2013, 19, 16424−16430.

157. Zhenling Chen, Lili Lin, Min Wang, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Synthesis of trans-β-Lactams by a Kinugasa Reaction on Water, Chem. Eur. J. 2013, 19, 7561–7567.

158. Jing Wang, Xiaohua Liu,* Shunxi Dong, Lili Lin, Xiaoming Feng,* Asymmetric Organocatalytic Cyclopropanation of Cinnamone Derivatives with Stabilized Sulfonium Ylides, J. Org. Chem. 2013, 78, 6322‒6327.

159. Yang Yang, Shunxi Dong, Xiaohua Liu,* Lili Lin, Xiaoming Feng,* Chiral Guanidine-Catalyzed Asymmetric Direct Vinylogous Michael Reaction of α,β-Unsaturated γ-Butyrolactams with Alkylidene Malonates, Chem. Commun. 2012, 48, 5040–5042.

160. Xiao Xiao, Xiaohua Liu,* Shunxi Dong, Yunfei Cai, Lili Lin, Xiaoming Feng,* Asymmetric Synthesis of 2,3-Dihydroquinolin-4-one Derivatives Catalyzed by Chiral Bisguanidium Salt, Chem. Eur. J. 2012, 18, 15922–15925. 

161. Yangbin Liu, Xiaohua Liu*, Min Wang, Peng He, Lili Lin, Xiaoming Feng*, Enantioselective Synthesis of 3,4-Dihydropyran Derivatives via Organocatalytic Michael Reaction of α,β-Unsaturated Enones, J. Org. Chem. 2012, 77, 4136–4142.

162. Xiaohua Liu, Lili Lin, Xiaoming Feng,* Chiral N,N¢-Dioxides: New Ligands and Organocatalysts for Catalytic Asymmetric Reactions, Acc. Chem. Res. 2011, 44, 574–587.

163. Shunxi Dong, Xiaohua Liu,* Yulong Zhang, Lili Lin, and Xiaoming Feng,* Asymmetric Synthesis of 3,4-Diaminochroman-2-ones Promoted by Guanidine and Bisguanidium Salt, Org. Lett. 2011, 13, 50605063. 

164. Jing Wang, Wentao Wang, Xiaohua Liu,* Zongrui Hou, Lili Lin, Xiaoming Feng,* Highly Enantioselective Direct Michael Addition of 1H-Benzotriazole to Chalcones Catalyzed by Sc(OTf)3/N,N¢-Dioxide Complex, Eur. J. Org. Chem. 2011, 2039–2042.

165. Xiaohong Chen, Shunxi Dong, Zhen Qiao, Yin Zhu, Mingsheng Xie, Lili Lin, Xiaohua Liu,* Xiaoming Feng,* Guanidine Organocatalyst for the Asymmetric Mannich-Type Reaction between α-Isothiocyanato Imide and Sulfonyl Imines, Chem. Eur. J. 2011, 17, 2583–2586.

166. Min Wang, Lili Lin, Jian Shi, Xiaohua Liu,* Yulong Kuang, Xiaoming Feng,* Asymmetric Crossed-Conjugate Addition of Nitroalkenes to Enones by a Chiral Bifunctional Diamine Organocatalyst, Chem. Eur. J. 2011, 17, 2365–2368.

167. Peng He, Xiaohua Liu,* Jian Shi, Lili Lin, Xiaoming Feng,* Organocatalytic Sequential Michael Reactions: Stereoselective Synthesis of Multifunctionalized Tetrahydroindan Derivatives, Org. Lett. 2011, 13, 936939.

168. Zhenhua Dong, Xiaohua Liu,* Juhua Feng, Min Wang, Lili Lin, Xiaoming Feng,* Efficient Asymmetric Synthesis of 4H-Chromene Derivatives through a Tandem Michael Addition–Cyclization Reaction Catalyzed by a Salen–Cobalt(II) Complex, Eur. J. Org. Chem. 2011, 137–142.

169. Xuan Fu, Juhua Feng, Zhenhua Dong, Lili Lin, Xiaohua Liu,* Xiaoming Feng,* Enantioselective Synthesis of 2-Substituted-1,5-Benzodiazepines through Domino Reaction of o-Phenylenediamine and Chalcone Derivatives, Eur. J. Org. Chem. 2011, 52335236.

170. Yonghai Hui, Weiliang Chen, Wentao Wang, Jun Jiang, Yunfei Cai, Lili Lin, Xiaohua Liu,* and Xiaoming Feng,* Highly Enantioselective Zinc-Catalyzed Friedel–Crafts Alkylation of Indoles with Ethyl Trifluoropyruvate, Adv. Synth. Catal. 2010, 352, 3174–3178.

171. Xiaohua Liu, Lili Lin, Xiaoming Feng,* Amide-Based Bifunctional Organocatalysts in Asymmetric Reactions, Chem. Commun. 2009, 45, 6145−6158.

172. Xiaohua Liu, Bo Qin, Bin He, Xiaoming Feng,* Catalytic Asymmetric Cyanosilylation of Ketones by a Chiral Amino Acid Salt, J. Am. Chem. Soc. 2005, 127, 12224−12225.

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