简历
主要教育和工作经历
2023.9- 四川大学化学学院，副教授
2018.5-2023.9 四川大学化学学院，特聘副研究员
2015.6-2017.12 清华大学化学系，博士后；合作导师：刘强教授
2009.9-2015.4 华南理工大学，化学与化工学院，有机化学专业，博士(指导老师：曾伟教授)
2005.9-2009.7 华南农业大学，理学院，应用化学毕业，学士(指导老师：倪春林教授)
主要研究方向
研究兴趣：
1.基于天然产物全合成的串联环化反应研究
2.天然产物全合成
科研项目：
1.国家自然科学基金面上项目(2026.1-2029.12)，项目批准号：22571207，主持
2.国家自然科学基金面上项目(2024.1-2027.12)，项目批准号：22371192，主持
3.四川省科技厅，面上项目(2023.1-2024.12)，项目批准号：2023NSFSC0105，主持
4.四川大学“从0到1”创新项目，2021, 主持
5.四川大学双百B人才项目, 2021，主持
6.国家自然科学基金青年基金项目(2020.1-2022.12), 项目批准号：21901170, 主持
7.国家自然基金委-区域创新联合发展基金，项目批准号：U19A2014，参与
8.四川大学引进人才科研启动经费项目(2019-2021)
9.中国博士后科学基金，二等(2015-2017)
获得奖励：
1.四川大学2021年度本科课堂教学质量优秀奖, 2022
2.四川大学2022届本科优秀毕业论文二等奖，指导教师，2022
3.四川省特聘专家, 2021
4.博士后创新研究基金, 华南理工大学, 2012
5.华南理工大学学术论文奖, 2011 和 2015
6.华南理工大学研究生新生一等奖学金，2009
7.华南农业大学学生二等奖学金, 2009
8.华南农业大学优秀毕业论文，2009
代表性成果 (获奖成果、专著、论文、专利)
聚焦天然产物合成领域 “简洁性与高效性” 核心科学问题，以 “发展有机合成串联反应新策略、突破天然产物简洁性合成瓶颈”为研究主线，取得系列创新性成果：1) 创新光催化烯醇硅醚的自由基串联反应，实现 C-20 氧化对映-贝壳杉烷二萜 sculponin U 全合成，解决该类二萜桥环骨架高效构筑的挑战；2）开发铁催化还原性 aldol 串联反应，8 步完成丁香烷倍半萜 rumphellclovane E 不对称全合成，这是少数铁催化缺电子烯烃的还原 aldol 反应成功应用于复杂产物全合成的实例。3) 设计钯催化半片呐醇重排串联 Csp2-H 芳基化反应，构建氢醌倍半萜 dysiherbols A-C 四环核心骨架，解决了氢醌类天然产物中连续季碳手性中心构建的挑战。4) 发展了甲酰基迁移/逆羟醛缩合/羟醛缩合/环氧化串联反应策略，首次成功构建了环氧瑞香烷二萜的正确环氧构型。5) 发展了光催化 de Mayo 碎裂化反应构筑巨大戟烷二萜三环核心骨架，有效解决复杂张力环系的构建难题。累计发表论文 62篇，它引超过 1700 次，其中以第一(共同)或者共同通讯作者发表论文44篇，包括 J. Am. Chem. Soc. 发表 2 篇， Angew. Chem. Int. Ed. 发表 2 篇，Org. Lett. 9篇，Chem. Comm. 1篇，Org. Chem. Front. 5篇，Chem. Eur J. 2篇，J. Org. Chem. 2篇；两篇论文入选ESI高被引论文，2篇论文引用超过300次。
Selected papers:
29.Wei Cao, Zhen Wang, Yan Hao, Tianli Wang, Shaomin Fu* and Bo Liu*. Total Synthesis of Sculponin U, A C-20 Oxygenated ent-Kaurane Diterpenoid, through Photoinduced Radical Cascade Cyclization. Angew. Chem. Int. Ed., 2023, 52, e202305516. 被微信公众号“化学谷”，“化学深耕堂”，“合成化学与分子表征”和“研之成理”推送介绍
28.Kanyu Yuan, Zhiyuan Li, Boning Li, Jinxuan Yang, Shaomin Fu,* and Bo Liu* . The Nazarov Renaissance: Strategic Electrocyclizations an Cascade Tactics in the Synthesis of Complex Molecules. Chem. Eur. J., 2026, accepted.
27. Shaomin Fu, Zhiyuan Li, Kanyu Yuan, Jinxuan Yang, Boning Li, Hong Yan,* Bo Liu*. Highlights of Modern Strategies for the Construction of Multiple Cycles in Natural Products and Bioactive Products. Org. Chem. Front., 2026, ASAP.
26.Zhuang Wang, Zhaoyu Zhang, Xinyu Xie, Yan Hao, Shaomin Fu* and Bo Liu*. Asymmetric Synthesis of the Tricyclic Core of Ingenane Diterpenoids via a Photocatalytic de Mayo Fragmentation Strategy. Org. Lett., 2026, 28, 1580–1585.
25.Zhuang Wang, Zhaoyu Zhang, Xinyu Xie, Song Qin, Shaomin Fu*, Bo Liu*. Construction of the Tricyclic Core of Rhamnofolane-type Diterpenoids. Org. Chem. Front., 2026, 13, 1617.
24. Canhui Tu, Yunlong Yang, Jiaxin Du, Cichang Ling, Shaomin Fu*, Bo Liu*. Asymmetric Construction of the Tricyclic Core Structure of Prostratin. Org. Lett., 2025, 27, 1579.
23. Shaomin Fu, Bo Liu*. Naturally Occurring [4+2] Type Terpenoid Dimers Assembled through Unmatched-electron-demand Cycloaddition. Chem. Eur. J., 2024, 30, e202402786
22.Jiaxin Du, Shaomin Fu* and Bo Liu*. A Photo-induced Radical Cascade Cyclization for the Synthesis of Angularly Fused Tricyclic Compounds. Org. Lett., 2024, 26, 4721–4726.
21. Shaomin Fu, and Bo Liu*. Total Synthesis with Gram-scale Radical Process: An Inspiration for Pharmaceutical Industry. Org. Process. Res. Dev., 2024, 28, 847–859.
20. Ying Sun, Jing Feng, Song Qin, Shaomin Fu* and Bo Liu*. Asymmetric Construction of the Core of C6, C7-Epoxy Daphnane Diterpenoid Orthoesters. Org. Lett., 2023, 25, 8072–8076.
19. Ganxing Huang, Zhengsong Huang, and Xianjian Ma, Zhihu Feng, Fengxia Yuan, Song Qin, Shaomin Fu* & Bo Liu *. Asymmetric Total Syntheses of Sarbracholide and Shizukaol B. Org. Chem. Front., 2023., 10, 3591-3597.
18. Lizhi Xun, Zhijiang Zhang, Yuqiao Zhou, Song Qin*, Shaomin Fu*, and Bo Liu. Stereo-divergent Construction of [5, 5]-Oxaspirolactone of Phainanoids. J. Org. Chem., 2023, 88, 3987-3991.
17. Mengqin Hu, Wei Cao, Zhen Wang, Yan Hao, Ganxing Huang, Yuqiao Zhou, Song Qin, Shaomin Fu,* and Bo Liu*. Construction of Angularly Fused Tricyclic Compounds via Photo-induced Radical Cascade Cyclization. Chin. J. Chem., 2023, 41, 2502—2506.
16. Cichang Ling, Zhengsong Huang, Yuqiao Zhou, Shaomin Fu*, and Bo Liu*. Alternative Construction of the Core of Lindenane Sesquiterpenoid. Chin. J. Chem., 2023, 41, 1931-1936.
15. Guoshen, Shaomin Fu*., Bo Liu*. Oxime Ester-Enabled Anti-Markovnikov Hydrosilylation of Alkenes. Chem. Commun., 2022, 58(87), 12204-12207.
14. Rong Liu, Mengwei Xia, Cichang Ling, Shaomin Fu*, Bo Liu*. Construction of the Tetracyclic Core Structure of Dysiherbols A−C. Org. Lett., 2022, 24(8), 1642-1646. Highlighted by CBG 资讯.
13. Ying Xie, Wei Huang, Song Qin, Shaomin Fu* and Bo Liu *, Catalytic Radical Cascade Cyclization of Alkene-Tethered Enones to Fused Bicyclic Cyclopropanols. Org. Chem. Front., 2021, 8, 6678-6686.
12. Yi Man, Chengying Zhou, Shaomin Fu*, Bo Liu*. Synthetic Study Aiming at Tricyclic Core of 12-epi-JBIR-23/24. Org. Lett., 2021, 23, 3151-3156.
11. Guanggen Liu+, Zhijiang Zhang+, Shaomin Fu*, Bo Liu*. Asymmetric Total Synthesis of Rumphellclovane E. Org. Lett., 2021, 23, 209-295. + These authors contribute equally to this article. Top ten downloaded article in Organic Letters in December 2020. Highlighted by synfacts, Synfacts 2021, 17(03), 248.;
10. Shaomin Fu, Bo Liu.* Recent Progress on Synthesis of Limonoids and Limonoid-like Natural Products. Org. Chem. Front., 2020, 7(14), 1903-1947 (review)
9. Bo Liu*, Shaomin Fu, Chengying Zhou. Nat. Prod. Rep., 2020, 37, 1627 - 1660. (review)
8. Guili Zhu, Chengying Zhou, Song Chen, Shaomin Fu*, Bo Liu*. Construction of BCDEF Core of Andilesin C. Org. Lett., 2019, 19, 7809.
7. Jing Feng, Hongli Yin, Yi Man, Shaomin Fu* and Bo Liu*. Chin. J. Chem. 2018, 36, 831-836. ● Selected as back cover paper.
Prior to Sichuan University
6. Shaomin Fu, † Zhihui Shao, † Yujie Wang, Qiang Liu*. J. Am. Chem. Soc., 2017, 139, 11941-11948. († Co-first Author.). Hightlighted by X-MOL. Highly Cited Paper (287 times).
5. Shaomin Fu, † Nan-Yu Chen, † Xufang Liu, † Zhihui Shao, Shu-Ping Luo, and Qiang Liu*. J. Am. Chem. Soc., 2016, 138, 8588-8594. († Co-first Author.). Highly Cited Paper (286 times).
4. Zhihui Shao, † Shaomin Fu, † Mufeng Wei, Shaolin Zhou, Qiang Liu*. Angew. Chem. Int. Ed., 2016, 55, 14653- 14657. († Co-first Author.). Highlighted by Chin. J. Org. Chem. 2017, 37, 242-244. (166 times)
3. Shaomin Fu, Honghao Yang, Guoqiang Li, Yuanfu Deng, Huanfeng Jiang and Wei Zeng *. Org. Lett., 2015, 17(4), 1018- 1021.
2. Shaomin Fu, Huanfeng Jiang, Yuanfu Deng, and Wei Zeng *. Adv. Synth. Catal. 2011, 353, 2795- 2804.
1. Libo Liang, † Shaomin Fu, † Dongen Lin, Xiao-Qi Zhang, Yuanfu Deng, Huanfeng Jiang and Wei Zeng*. J. Org. Chem., 2014, 79, 9472- 9480. († Co-first author.)
