主要研究方向

手性配体或催化剂的设计合成及其在不对称催化中的应用

金属有机化学

主要工作业绩

研究经历

董顺喜博士毕业于四川大学，师从冯小明教授，博士研究方向主要是手性胍类小分子催化剂的设计、合成及其在吖内酯参与的环化反应中的应用。2013作为洪堡学者赴德国亚琛工业大学Carsten Bolm教授课题组开展博士后研究工作，主要从事氨基酸衍生的pentathiepin设计合成以及手性氮杂环卡宾(NHC)催化不对称转化领域研究。2016年，加入德国明斯特大学Gerhard Erker课题组，开展主族元素有机化学研究，主要开展新型受阻Lewis酸碱对(FLP)的设计合成及其反应性研究。目前为止，已取得一系列创新性的研究成果, 在Chem. Soc. Rev., J. Am. Chem. Soc.,   Angew. Chem. Int. Ed., Org. Lett., Chem. Commun., Chem. -Eur. J. 以及 Dalton. Trans. 等刊物发表 SCI 论文30余篇，多篇工作被Synfacts杂志刊登并给予高度评价。其中以第一作者身份发表   SCI 论文7篇，共同通讯作者论文5篇。

主要奖励及荣誉

2019 四川省千人计划青年项目

2019 四川大学“校百人计划”

2013 德国洪堡学者博士后奖学金

2011 教育部“博士研究生学术新人奖”

代表性成果 (获奖成果、专著、论文、专利)

论文发表情况

(1) Tang, Q.; Fu, K.;   Ruan, P. R.; Dong, S. X.*;   Su, Z. S; Liu, X. H.; Feng, X. M.*,   Asymmetric Catalytic Formal   1,4-Allylation of β,γ-Unsaturated α-Ketoesters   via   Allylboration/Oxy-Cope Rearrangement, Angew. Chem. Int. Ed. 2019, 58,     11846.

(2) Xiong, Q. Li, G. L.; Dong,   S. X.*; Liu, X. H.;   Feng, X. M.*, Enantioselective Synthesis of   Hydrothiazole Derivatives   via Isocyanide-based Multicomponent Reaction, Org.   Lett. 2019,   accepted.

(3) Liu, W.; Zhou, P. F.;   Lang, J. W.; Dong, S. X.*;   Liu, X. H.; Feng, X. M.*, A   nickel(II)-catalyzed asymmetric   intramolecular Alder-ene reaction of   1,7-dienes, Chem. Commun. 2019,   55, 4479.

(4) Li, X. Q.; Xiong, Q.;   Guan, M. M.; Dong, S. X.*;   Liu, X. H.; Feng, X. M.*, Divergent   Synthesis of Enantioenriched   β-Functional Amines via Desymmetrization of   meso-Aziridines with   Isocyanides, Org. Lett. 2019, 21, 6096.

(5) Dong, S. X.;   Feng, X. M.; Liu, X. H.* Chiral   Guanidine and Their Derivatives in Asymmetric Synthesis, Chem. Soc. Rev.   2018, 47, 8525.

(6) Zhong, X.; Tang, Q.,   Zhou, P. F.; Zhong, Z. W. Dong,   S. X.*; Liu, X. H.; Feng, X. M.*,   Asymmetric Synthesis of   Polysubstituted Methylenecyclobutanes via Catalytic   [2+2] Cycloaddition   Reaction of N-Allenamides, Chem. Commun. 2018, 54, 10511.

(7) Dong, S. X.;   Frings, M.; Cheng, H. C.; Wen,   J.; Zhang, D.; Rabbe, G.; Bolm, C.*   "Organocatalytic Kinetic   Resolution of Sulfoximines" J. Am. Chem.   Soc. 2016, 138, 2166.   Highlight by Synfacts (2016, 634)

(8) Dong, S. X.;   Liu X. H*.; Zhu, Y.; He, P.; Lin,   L. L.; Feng, X. M.* "Organocatalytic   Oxyamination of Azlactones:   Kinetic Resolution of Oxaziridines and Asymmetric   Synthesis of   Oxazolin-4-ones" J. Am. Chem. Soc. 2013, 135, 10026.   Highlight by   Synfacts (2013, 1006)

(9) Dong, S. X.;   Liu, X. H.; Chen, X. H.; Mei, F.;   Gao, B.; Lin, L. L.; Feng, X. M.*   "Chiral Bisguanidine-Catalyzed Inverse-Electron-Demand     Hetero-Diels-Alder Reaction of Chalcones with Azlactones" J. Am. Chem.     Soc. 2010, 132, 10650. Highlight by Synfacts (2010, 1105)

(10) Dong, S. X.;   Frings, M.; Zhang, D.; Guo. Q.   Q.; Danilliuc, C. G.; Cheng, H. C.; Bolm, C.*   "Organocatalytic   Asymmetric Synthesis of trans-γ-Lactams" Chem.   Eur. J. 2017, 23,   13888.

(11) Dong, S. X.;   Wang, L.; Wang, T.; Daniliuc, C.   G.; Brinkkötter, M.; Eckert, H.; Kehra. G.;   Erker, G. "Formation   and Reactions of Active Five-membered   Phosphane/borane Frustrated   Lewis Pair Ring Systems" Dalton Trans. 2018,   47, 4449.

(12) Dong, S. X.;   Liu, X. H*.; Zhang, Y. L.; Lin,   L. L.; Feng, X. M *. "Asymmetric   Synthesis of   3,4-Diaminochroman-2-ones Promoted by Guanidine and Bisguanidium     Salt" Org. Lett. 2011, 13, 5060.

(13) Liu,   X. H.; Dong, S.   X.; Lin, L. L.; Feng, X. M.* " Chiral   Amino Acids-Derived Catalysts   and Ligands " Chin. J. Chem, 2018,   36, 791.

(14) Guo,   J.; Dong, S. X.;   Zhang, Y. L.; Kuang, Y. L.; Feng, X. M.*   "Chiral Scandium(III)-Catalyzed   Enantioselective α-Arylation of   N-Unprotected 3-Substituted Oxindoles with   Diaryliodonium Salts"   Angew. Chem., Int. Ed. 2013, 52, 10245. Highlight   by Synfacts (2013,   1262)

(15) Wang,   L.; Dong, S.   X.; Daniliuc, C. G.; Liu, L.; Grimme, S.; Knitsch,   R.; Eckert, H.;   Hansen, M. R.; Kehra. G.; Erker, G."Formation of   Macrocyclic Ring   Systems by Carbonylation of Trifunctional P/B/B   Frustrated Lewis Pairs"   Chem. Sci. 2018, 9, 1544.

(16) Xu,   X.; Zhang, J. L.; Dong,   S. X.; Lin. L. L.; Lin, X. B.; Liu, X.   H.; Feng, X. M.*   "Nickel(II)-Catalyzed Asymmetric Propargyl   [2,3]-Wittig Rearrangement of   Oxindole Derivatives: A Remarkable   Chiral Amplification Effect" Angew.   Chem., Int. Ed. 2018, 57,   8734.

(17) Zhu,   Y.; Liu, X. H.;* Dong,   S. X.; Zhou, Y. H.; Li, W.; Lin, L. L.;   Feng, X. M.* "Asymmetric N-H   Insertion of Secondary and Primary   Anilines under the Catalysis of Palladium   and Chiral Guanidine   Derivatives" Angew. Chem., Int. Ed. 2014, 53, 1636.

(18) Wen,   J.; Cheng, H. C.; Dong,   S. X.; Bolm, C.* "Copper-Catalyzed   S-C/S-N Bond Interconversions"   Chem. Eur. J. 2016, 22, 5547.

(19) Chen,   X. Y.; Bohmann,   R. A.; Wang, L.; Dong, S. X.; Räuber, C.; Bolm,   C.*   "Palladium/Copper-Cocatalyzed Oxidative Amidobrominations of     Alkenes" Chem. Eur. J. 2015, 21, 10330.

(20)   Cheng, H.; Dong, W.;   Dannenberg, C. A.; Dong, S. X.; Guo, Q.;   Bolm, C.*   "Ruthenium-Catalyzed Hydroarylations of Oxa- and   Azabicyclic   Alkenes" ACS Cat. 2015, 5, 2770.

(21) Yao,   Q.; Yu, H.; Zhang,   H.; Dong, S. X.; Chang, F. Z.; Lin, L. L.;   Liu, X. H.; Feng, X. M.*   "Lewis acid catalyzed asymmetric [4+2]   cycloaddition of cyclobutenones   to synthesize α,β-unsaturated δ-lactones"   Chem. Commun. 2018, 54, 3375.

(22) Chen,   X. H.; Dong,   S. X.; Qiao, Z.; Zhu, Y.; Xie, M. S.; Lin, L. L.;   Liu, X. H.;* Feng, X.   M.* "Guanidine Organocatalyst for   Asymmetric Mannich-Type Reaction   between α-Isothiocyanato Imide and   Sulfonyl Imines" Chem. Eur. J. 2011,   17, 2583.

(23)   Zhang, Y. L.; Dong,   S. X.; Liu, X. H.; Xie. M. S.; Zhu, Y.;   Lin, L. L.; Feng, X. M.*   "Asymmetric Synthesis of   cis-4-Aminobenzopyran Derivatives Catalyzed by   N,N'-Dioxide-Sc(OTf)3   Complex" Chem. Eur. J. 2011, 17, 13684.

(24) Yang,   Y.; Dong, S.   X.; Liu, X. H.; Lin, L. L.; Feng, X. M.*   "Chiral guanidine-catalyzed   asymmetric direct vinylogous Michael   reaction of α,β-unsaturated   γ-butyrolactams with alkylidene   malonates" Chem. Commun., 2012, 48,   5040.

(25) Xiao,   X.; Liu X. H*.; Dong,   S. X.; Cai, Y. F.; Lin, L. L.; Feng, X.   M.* "Asymmetric Synthesis of   2,3-Dihydroquinolin-4-one   Derivatives Catalyzed by Chiral Bisguanidium   Salt" Chem. Eur. J.   2012, 18, 15922.

(26) Zhu,   Y.; Xie, M. S.; Dong,   S. X.; Zhao, X. H.; Lin, L. L.; Liu, X.   H.; Feng, X. M.* "Asymmetric   Cycloaddition of β,γ-Unsaturated α-Ketoesters   with Electron-Rich Alkenes   Catalyzed by a Chiral Er(OTf)3/N,N′-Dioxide   Complex: Highly Enantioselective   Synthesis of   3,4-Dihydro-2H-pyrans" Chem. Eur. J. 2011, 17, 8202.

(27) Wang,   J.; Liu, X. H.;* Dong,   S. X.; Lin, L. L.; Feng, X. M.* "Asymmetric   Organocatalytic   Cyclopropanation of Cinnamone Derivatives with   Stabilized Sulfonium   Ylides" J. Org. Chem., 2013, 78, 6322.

(28)   Xiong, Y.; Wang, F.; Dong,   S. X.; Liu, X. H.; Feng, X. M.*   "Asymmetric Bisprolinamide-Catalyzed   Cross-Aldol Reaction of   Aldehydes" Synlett. 2008, 1, 73.

(29) Zhu,   Y.; Chen, X. H.;   Xie, M. S.; Dong, S. X.; Qiao, Zhen.; Lin, L.   L.; Liu, X. H.; Feng, X.   M.* "Asymmetric Diels–Alder and   Inverse-Electron-Demand   Hetero-Diels–Alder Reactions of   β,γ-Unsaturated α-Ketoesters with   Cyclopentadiene Catalyzed by   N,N′-Dioxide Copper(II) Complex" Chem. Eur.   J. 2010, 16, 11963.

(30)   Wen, Y. H.; Gao, B.;   Fu, Y. Z.; Dong, S. X.; Liu, X. H.; Feng,   X. M.* "Asymmetric   Three-Component Strecker Reactions Catalyzed   by   trans-4-Hydroxy-L-proline-Derived N,N′-Dioxides" Chem. Eur. J.   2008, 14,   6789.