Research Interests
Biomimetic Asymmetric Catalysis
Chiral Peptide Phosphonium Salt (PPS) Catalysis
Asymmetric Synthetic Chemistry
Mechanistic Studies
New Synthetic Methodologies for Biologically Active Molecules
Education and Academic Career
2016.09—Present, College of Chemistry, Sichuan University, Professor
2012.06—2016.08, National University of Singapore，Postdoctoral Research Fellow, Collaborating Advisor: Prof. Yixin Lu
2011.08—2012.05, Institute of Chemistry, Chinese Academy of Sciences, Assistant Researcher
2006.09—2011.07, Institute of Chemistry, Chinese Academy of Sciences, Ph.D. in Organic Chemistry, Advisor: Prof. Qing-Hua Fan
2002.09—2006.07, Sichuan University, B.S. in Applied Chemistry，Advisors: Prof. Xiao-Ming Feng and Prof. Qing-Hua Fan
Honors and Awards
2026，National Natural Science Foundation of China Young Scientists Fund Type A (formerly the National Science Fund for Distinguished Young Scholars)
2026，China-Singapore Synthetic Chemistry Award
2026，Outstanding Ph.D. Dissertation Supervisor, Sichuan University (Ph.D. student: Yan Guo)
2025，CAST Young Talent Support Program, Doctoral Special Program Supervisor (Ph.D. students: Zanjiao Liu, Fan Wang)
2025，Outstanding Undergraduate Graduates Supervisor, Sichuan Province (Students: Jialu Chen, Naixin Zhang)
2025，Outstanding Undergraduate Graduation Design Supervisor, Sichuan University（Undergraduate student: Jialu Chen）
2024，Industrial Professor, Chengdu High-tech Industrial Development Zone
2024，Sichuan Academic and Technical Leader
2024，Nominated Outstanding Ph.D. Dissertation Supervisor, Sichuan University (Ph.D. student: Jiahong Wu)
2024，CAST Young Talent Support Program, Doctoral Special Program Supervisor (Ph.D. students: Fengyuan Guo)
2023，Young Investigator Award, 24th International Conference on Phosphorus Chemistry
2023，Outstanding Oral Presentation Award, 23rd International Conference on Organic Synthesis
2023，Outstanding Ph.D. Dissertation Supervisor, Sichuan University（Ph.D. student: Hongkui Zhang）
2023，Outstanding Undergraduate Graduation Design Supervisor, Sichuan University（Undergraduate: Ao Xu）
2022，National Natural Science Foundation of China Young Scientists Fund Type B (formerly the National Science Found for Excellent Young Scholars)
2022，Sichuan Provincial Science Fund for Distinguished Young Scholars
2022，Thieme Chemistry Journals Award
2022，Outstanding Ph.D. Dissertation Supervisor, Sichuan University (Ph.D. student: Si-Qiang Fang)
2022，Outstanding Undergraduate Graduation Design Supervisor, Sichuan University（Undergraduate: Bowei Zhou）
2020，Outstanding Mentor for Innovation, Entrepreneurship and Practical Education, Sichuan University
2020，Outstanding Mentor for the Cultivation of Top Innovative Talents, Sichuan University
2019，ACP Lectureship Award
2019，Outstanding Mentor for the Cultivation of Top Innovative Talents, Sichuan University
2019，Outstanding Mentor for Undergraduate Innovation and Entrepreneurship Education, Sichuan University
2019，First Prize for Outstanding Undergraduate Graduation Design Supervisor, Sichuan University
2019，Outstanding Female Achievement Award, Sichuan University
2019，Specially Appointed Expert of Chengdu
2018，Specially Appointed Expert of Sichuan Province
2018，Outstanding Undergraduate Graduation Design Supervisor, Sichuan University
2018，Outstanding Supervisor for Cultivation of Top-Notch Innovative Talents, Sichuan University
2018，Outstanding Supervisor for Undergraduate Innovation, Entrepreneurship, and Practice Education, Sichuan University
2017，National Young Thousand Talents Program
2017，Sichuan Provincial Young Thousand Talents Program
2017，Young Scientist Award, China Science and Technology Daily / Scientific Chinese 2017 Annual Figures
2017，Sichuan University Young Scientific and Technological Talent Award
2017，Sichuan University Future Excellent Scholar Award
2016，Gold Award of Outstanding Mentor for “Singapore Science and Engineering Fair (SSEF, 2016), Ministry of Education, Singapore
Prior to 2016, See the research group website for additional awards and honors
Editorial Boards
2026.01—Present, Young Editorial Board Member, Science China Chemistry
2025.01—Present, Young Editorial Board Member, Chinese Chemical Letters
2023.01—Present, Young Editorial Board Member, Chinese Journal of Organic Chemistry
2023.01—Present, Committee Member, Chirality Chemistry Committee, Chinese Chemical Society
2022.01—Present, Young Editorial Board Member, Green Synthesis & Catalysis
2022.01—2024.12, Early Career Advisory Board Member, Science of Synthesis
Representative Publications (see more on the research group website)
87. Siqiang Fang,+ Zanjiao Liu,+ Fan Wang,+ Tianli Wang* "Bioinspired Chiral Peptide–Phosphonium Salt Catalysis: From Enzymes to Cationic Small-Molecule Enzyme Mimics" Acc. Chem. Res. 2025, 58(13), 2088-2109.
86. Fan Wang,+ Jian-Ping Tan,+ Ganlu Qian,+ Siqiang Fang, Zanjiao Liu, Kehan Li, Jiayan Zheng, Jia-Hong Wu, Xin Hong,* Tianli Wang* "Stepwise-Controllable Catalytic Asymmetric Atherton–Todd Reaction to Access Diverse P(V)-Stereogenic Compounds" Nat. Chem. 2026, 18(1), 23-32. (selected as Front Cover by Nat. Chem.; highlighted by Nat. Chem. 2026, 18, 6-7.)
85. Yan Guo,+ Lu Yu,+ Siqiang Fang,+ Shanshan Ding, Zhaowei Bao, Jixing Che, Xiao-Song Xue,* Tianli Wang* "Atroposelective organocatalytic nucleophilic aromatic substitution for C–O bond construction" Nat. Catal. 2026, 9(1), 448-459.
84. Jingxuan Wei,+ Siqiang Fang,+ Zanjiao Liu,+ Jia-Hong Wu, Xingjie Luo, Yichao Wang,* Fan Wang, Xingtao Zheng, Tianli Wang* "Synergistic Ion-Pair/Lewis Acid Catalysis Enables Enantioselective Synthesis of Helically Chiral Oxa[6]Helicenes" Angew. Chem. Int. Ed. 2026, 65(12), e5562213.
83. Yan Guo,+ Siqiang Fang,+ Lixiang Zhu,+ Jintong Song, Jixing Che, Haifeng Xiang, Tianli Wang* "Stereodivergent Access to C-N Atropisomers via Phosphonium Salt-Enabled Desymmetrizing Remote Cyclization/Aromatization Cascade" Angew. Chem. Int. Ed. 2026, 65(1), e18310. (Very Important Paper by Angew Chem. Int. Ed.)
82. Jia-Hong Wu,+ Qing Yang,+ Mengwei You,+ Jingxuan Wei, Fangfang Zhang, Liejin Zhou,* Tianli Wang* "Enantioselective Synthesis of Chiral Azepines: A Cascade Strategy Featuring 1-Aza-Cope Rearrangement" Angew. Chem. Int. Ed. 2025, 64(42), e202514823. (Hot Paper by Angew Chem. Int. Ed.)
81. Siqun Yang,+ Xingjie Luo,+ Zanjiao Liu,+ Siqiang Fang,* Jia-Hong Wu, Tianli Wang* "Bioinspired Peptide-Phosphonium Salt Catalysis Unlocks Asymmetric Desymmetrization of Phosphoryl Acids: Programmable Synthesis of P(V)-Stereogenic Molecules" Angew. Chem. Int. Ed. 2025, 64(39), e202510513.
80. Zhengdong Wu,+ Siqiang Fang,+ Jiajia He, Jixing Che, Zanjiao Liu, Xin Wei,* Zhishan Su, Tianli Wang* "Desymmetrization/Kinetic Resolution of Planar Chiral [2.2]Paracyclophanes by Bioinspired Peptide-Iminophosphorane Catalysis" Angew. Chem. Int. Ed. 2025, 64(17), e202423702.
79. Siqiang Fang,+ Zhaowei Bao,+ Zanjiao Liu, Zhengdong Wu, Jian-Ping Tan, Xin Wei,* Bo Li, Tianli Wang* "Cationic Foldamer-Catalyzed Asymmetric Synthesis of Inherently Chiral Cages" Angew. Chem. Int. Ed. 2024, 63(46), e202411889.
78. Zanjiao Liu,+ Siqiang Fang,+ Haoze Li,+ Chunxiu Xiao, Kai Xiao, Zhishan Su,* Tianli Wang* "Organocatalytic Skeletal Reorganization for Enantioselective Synthesis of S-stereogenic Sulfinamides" Nat. Commun. 2024, 15(1), 4348.
77. Lingzhu Chen, Youlin Deng, Tingting Li, Deyu Hu,* Xiaoyu Ren, Tianli Wang* "Asymmetric Nucleophilic Additions Promoted by Quaternary Phosphonium Ion-Pair Catalysts" CCS Chemistry. 2024, 6, 2110-2130. (Selected as an “Outstanding Review Article” by CCS Chemistry)
76. Jia-Yan Zheng, Fan Wang, Yan Zhang, Zheng Zheng, Jia-Hong Wu, Xiaoyu Ren, Zhishan Su, Wenchuan Chen,* Tianli Wang* "Novel Stereo-Induction Pattern in Pudovik Addition/Phospha-Brook Rearrangement towards Chiral Trisubstituted Allenes" Angew. Chem. Int. Ed. 2024, 63(22), e202403707. (Hot Paper by Angew Chem. Int. Ed.; highlighted by Pengfei Li,* Chin. J. Org. Chem. 2024, 44, 2059-2060.)
75. Jia-Hong Wu, Siqiang Fang, Xingtao Zheng, Jiajia He, Yi Ma, Zhishan Su, Tianli Wang* "Organocatalytic Dynamic Kinetic ResolutionEnabled Asymmetric Synthesis of Phosphorus-Containing Chiral Helicenes" Angew. Chem. Int. Ed. 2023, 62(49), e202309515. (highlighted by Benjamin List, Synfacts, 2024, 20, 76.)
74. Fengyuan Guo,+ Siqiang Fang,+ Jiajia He,+ Zhishan Su* and Tianli Wang* "Enantioselective Organocatalytic Synthesis of Axially Chiral Aldehyde-containing Styrenes via SNAr Reaction-Guided Dynamic Kinetic Resolution" Nat. Commun. 2023, 14(1), 5050.
73. Siqiang Fang,+, Zanjiao Liu,+ Tianli Wang* "Design and Application of Peptide-Mimic Phosphonium Salt Catalysts in Asymmetric Synthesis" Angew. Chem. Int. Ed. 2023, 62(47), e202307258.
72. Jia-Hong Wu,† Jian-Ping Tan,† Jia-Yan Zheng,† Jiajia He, Zhenlei Song,* Zhishan Su, Tianli Wang* "Towards Axially Chiral Pyrazole-Based Phosphorus Scaffolds by Dipeptide-Phosphonium Salt Catalysis" Angew. Chem. Int. Ed. 2023, e202215720. (highlighted by Chin. J. Org. Chem. 2023, 43, 1208 and Chem. Catal. 2023, 3, 100579.)
71. Yuan Chen,† Jiajia He,† Cheng Zhuang, Zanjiao Liu, Kai Xiao, Zhishan Su,* Xiaoyu Ren, Tianli Wang* "Synergistic Catalysis between a Dipeptide Phosphonium Salt and a Metal-Based Lewis Acid for Asymmetric Synthesis of N-Bridged [3.2.1] Ring Systems" Angew. Chem. Int. Ed. 2022, e202207334. (Selected as the Inside Back Cover by Angew Chemie)
70. Lixiang Zhu, Heling Peng, Yan Guo, Jixing Che, Jia-Hong Wu, Zhishan Su, Tianli Wang* "Enantioselective Synthesis of Atropisomeric Biaryl Phosphorus Compounds by Chiral Phosphonium-Salt-Enabled Cascade Arene Formation" Angew. Chem. Int. Ed. 2022, e202202467.
69. Jian-Ping Tan,# Kehan Li,# Boming Shen,# Cheng Zhuang, Zanjiao Liu, Kai Xiao, Peiyuan Yu*, Bing Yi,* Xiaoyu Ren and Tianli Wang* "Asymmetric synthesis of N-bridged [3.3.1] ring systems by phosphonium salt/Lewis acid relay catalysis" Nat. Commun. 2022, 13, 357. (highlighted by Benjamin List*, Synfacts, 2022, 18, 666)
68. Hongkui Zhang,# Jiajia He,# Yayun Chen,# Cheng Zhuang, Chunhui Jiang,* Kai Xiao, Zhishan Su,* Xiaoyu Ren, and Tianli Wang* “Regio- and Stereoselective Cascade of β,γ-Unsaturated Ketones by Dipeptided Phosphonium Salt Catalysis: Stereospecific Construction of Dihydrofuro-Fused [2,3-b] Skeletons” Angew. Chem. Int. Ed. 2021, 60, 19860-19870.
67. Siqiang Fang#, Jian-Ping Tan#, Jianke Pan, Hongkui Zhang, Yuan Chen, Xiaoyu Ren, Tianli Wang* "Enantiodivergent Kinetic Resolution of 1,1'-Biaryl-2,2'-Diols and Amino Alcohols by Dipeptide-Phosphonium Salt Catalysis Inspired by the Atherton-Todd Reaction" Angew. Chem. Int. Ed. 2021, 60, 14921-14930. (Selected as the Frontispiece and Hot Paper by Angew. Chem. Int. Ed.)
66. Jianke Pan, Jia-Hong Wu, Hongkui Zhang, Xiaoyu Ren, Jian-Ping Tan, Lixiang Zhu, Hong-Su Zhang, Chunhui Jiang, Tianli Wang,* “Highly Enantioselective Synthesis of Fused Tri- and Tetrasubstituted Aziridines: aza-Darzens Reaction of Cyclic Imines with α-Halogenated Ketones Catalyzed by Bifunctional Phosphonium Salt”, Angew. Chem. Int. Ed. 2019, 58, 7425-7430. (Highlighted by Synlett. 2019, 30, 2101)
For a complete list of representative publications and research achievements, please visit the research group website: http://www.chem-wang.com/
