Faculty

Cao, Weidi     


Research direction: Asymmetric catalysis; organosilicon chemistry

Contact information: 86-28-85418249

Email: wdcao@scu.edu.cn

Professor

The website of group: http://www.scu.edu.cn/chem_asl

RESEARCH INTERESTS

Asymmetric catalysis; organosilicon chemistry

EDUCATION AND ACADEMIC CAREER

2021.9-present Professor, College of Chemistry, Sichuan University, Chengdu, China

2018.4-2021.8 Associate Professor, College of Chemistry, Sichuan University, Chengdu, China

2015.9-2018.2 Postdoctor, Division of Chemistry & Biological Chemistry, Nanyang Technological University, Singapore (with Prof. Choon-Hong Tan)

2010.9-2015.6 Ph.D., College of Chemistry, Sichuan University, China (with Prof. Xiaoming Feng)

2006.9-2010.6 B.Sc., College of Chemistry, Sichuan University, China

HONORS AND AWARDS

2021 High-level Talents Introduction Plan of Sichuan (Young Talents Program)

2021 The Young Scientific and Technological Academic Leaders Training Program of Sichuan University

2019 Higher Education Outstanding Scientific Research Output Awards (Science and Technology) from the Ministry of Education (First class, China)

2016 The 14th International Symposium for Chinese Organic Chemists (ISCOC) and the 11th International Symposium for Chinese Inorganic Chemists (ISCIC) poster award

PUBLICATIONS

1. Liuzhen Hou, Yuqiao Zhou, Han Yu, Tangyu Zhan, Weidi Cao,* Xiaoming Feng,* Enantioselective Radical Addition to Ketones through Lewis Acid-Enabled Photoredox Catalysis, J. Am. Chem. Soc. 2022, 144, 22140−22149.

2. Guihua Pan, Changli He, Min Chen, Qian Xiong, Weidi Cao,* Xiaoming Feng,* Synthesis of Dihydroisoquinoline and Dihydropyridine Derivatives via Asymmetric Dearomative Three-component Reaction, CCS Chem. 2022, 4, 20002008.

3. Liangkun Yang, Wang-Yuren Li, Liuzhen Hou, Tangyu Zhan, Weidi Cao,* Xiaohua Liu, Xiaoming Feng,* Nickel-catalyzed Asymmetric Photoenolization/Mannich Reaction of (2-Alkylphenyl) Ketones, Chem. Sci. 2022, 13, 8576–8582.

4. Fengcai Zhang, Xinpeng Sang, Yuqiao Zhou, Weidi Cao,* Xiaoming Feng,* Enantioselective Synthesis of Azetidines through [3 + 1]-Cycloaddition of Donor−Acceptor Aziridines with Isocyanides, Org. Lett. 2022, 24, 1513−1517.

5. Changqiang He, Zhikun Wu, Yuqiao Zhou, Weidi Cao,* Xiaoming Feng,* Asymmetric Catalytic Nitrooxylation and Azidation of β-Keto Amides/esters with Hypervalent Iodine Reagents, Org. Chem. Front. 2022, 9, 703−708.

6. Li Dai, Wen Liu, Yuqiao Zhou, Zi Zeng, Xinyue Hu, Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Halogenation/Semipinacol Rearrangement of 3-Hydroxyl-3-vinyl Oxindoles: A Stereodivergent Kinetic Resolution Process, Angew. Chem. Int. Ed. 2021, 60, 2659926603.

7. Mingming Guan, Shiyu Wang, Yao Luo, Weidi Cao,* Xiaohua Liu, Xiaoming Feng,* Catalytic Asymmetric Addition of Thiols to Silyl Glyoxylates for Synthesis of Multi-hetero-atom Substituted Carbon Stereocenter, Chem. Sci. 2021, 12, 7498–7503.

8. Mingyi Jiang, Kaiqi Hu, Yuqiao Zhou, Qian Xiong, Weidi Cao,* Xiaoming Feng,* Enantioselective Isocyanide-based Multicomponent Reaction with Alkylidene Malonates and Phenols, Org. Lett. 2021, 23, 5261–5265.

9. Weidi Cao, Xiaohua Liu,* Asymmetric Formal Hetero-Ene Reaction of Allylgold Intermediates, Chin. J. Org. Chem. 2021, 41, 857−858.

10. Ziwei Zhong, Zhijie Xiao, Xiaohua Liu, Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Synthesis of 3,2'-Pyrrolinyl Spirooxindoles via Conjugate Addition/Schmidt-type Rearrangement of Vinyl Azides and (E)-Alkenyloxindoles, Chem. Sci. 2020, 11, 11492−11497.

11. Liuzhen Hou, Tengfei Kang, Liangkun Yang, Weidi Cao,* Xiaoming Feng,* Enantioselective Imino-Ene Reaction of N-Sulfonyl Ketimines with Silyl Enol Ethers: Access to Chiral Benzosultams, Org. Lett. 2020, 22, 1390−1395.

12. Yu Zhang, Hao Pan, Wen Liu, Weidi Cao,* Xiaoming Feng,*Asymmetric Catalytic Synthesis of Epoxides via Three-Component Reaction of Diazoacetates, 2‑Oxo-3-ynoates, and Nitrosoarenes, Org. Lett. 2020, 22, 67446749.

13. Xiangqiang Li, Mingyi Jiang, Tangyu Zhan, Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Three-component Hydroacyloxylation/1,4-Conjugate Addition of Ynamides, Chem Asian J. 2020, 15, 1953−1956.

14. Weidi Cao, Xiaohua Liu, Xiaoming Feng,* Chiral N,Nʹ-dioxide and Their Metal Complexes in Asymmetric Catalysis (in Chinese), Chin. Sci. Bull. 2020, 65, 2941−2951.

15. Bin Shen, Wen Liu, Weidi Cao,* Xiaohua Liu, Xiaoming Feng,* Asymmetric Synthesis of α,β-Epoxy-γ-lactams through Tandem Darzens/Hemiaminalization Reaction, Org. Lett. 2019, 21, 47134716.

16. Yan Wang, Kaixuan Wang, Weidi Cao,* Xiaohua Liu, Xiaoming Feng,* Diastereo- and Enantioselective 1,6-Conjugate Addition of 2‑Azaarylacetamides to para-Quinone Methides, Org. Lett. 2019, 21, 6063−6067.

17. Weidi Cao, Xiaoming Feng, Xiaohua Liu,* Reversal of Enantioselectivity in Chiral Metal Complex-catalyzed Asymmetric Reactions, Org. Biomol. Chem. 2019, 17, 6538−6550.

18. Wen Liu, Weidi Cao,* Haipeng Hu, Lili Lin, Xiaoming Feng,* Dynamic Kinetic Asymmetric Transformations of β-Halo-α-Keto Esters by N,N′-Dioxide/Ni(II)-Catalyzed Carbonyl-Ene Reaction, Chem. Commun. 2018, 54, 89018904.

19. Hang Zhang, Qian Yao, Weidi Cao,* Shulin Ge, Jinxiu Xu, Xiaohua Liu and Xiaoming Feng,* Catalytic Enantioselective Ene-type Reactions of Vinylogous Hydrazone: Construction of α-Methylene-g-butyrolactone Derivatives, Chem. Commun. 2018, 54, 12511–12514.

20. Lifeng Wang, Weidi Cao,* Hongjiang Mei, Linfeng Hu, Xiaoming Feng,* Catalytic Asymmetric Synthesis of Chiral Spiro-Cyclopropyl Oxindoles from 3-Alkenyl-Oxindoles and Sulfoxonium Ylides, Adv. Synth. Catal. 2018, 360, 4089-4093. (VIP)

21. Changqiang He, Weidi Cao,* Jianlin Zhang, Shulin Ge, Xiaoming Feng,* Chirall N,N'-Dioxide/Scandium(III)-Catalyzed Asymmetric Alkylation of N-Unprotected 3-Substituted Oxindoles, Adv. Synth. Catal. 2018, 360, 4301-4305.

22. Weidi Cao, Xiaohua Liu,* Xiaoming Feng, Chiral Organobases: Properties and Applications in Asymmetric Catalysis, Chin. Chem. Lett. 2018, 29, 12011208.

23. Weidi Cao, Davin Tan, Richmond Lee,* Choon-Hong Tan,* Enantioselective 1,2-Anionotropic Rearrangement of Acylsilane through a Bisguanidinium Silicate Ion Pair, J. Am. Chem. Soc. 2018, 140, 19521955.

24. Weidi Cao, Xiaohua Liu, Jing Guo, Lili Lin, Xiaoming Feng,* Asymmetric Tandem 1,5-Hydride Shift/Ring Closure for the Synthesis of Chiral Spirooxindole Tetrahydroquinolines, Chem. Eur. J. 2015, 21, 16321636.

25. Weidi Cao, Xiaohua Liu, Ruixue Peng, Peng He, Lili Lin, Xiaoming Feng,* Catalytic Asymmetric Cross-Dehydrogenative Coupling: Activation of C–H Bonds by a Cooperative Bimetallic Catalyst System, Chem. Commun. 2013, 49, 34703472.

26. Weidi Cao, Xiaohua Liu, Wentao Wang, Lili Lin, Xiaoming Feng,* Highly Enantioselective Synthesis of Tetrahydroquinolines via Cobalt(II)-Catalyzed Tandem 1,5-Hydride Transfer/Cyclization, Org. Lett. 2011, 13, 600603.

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