冯小明博士： 教育部长江学者特聘教授，国家杰出青年科学基金获得者，国家人事部等七部委的“新世纪百千万人才工程”入选者，教育部《跨世纪优秀人才培养计划》入选者，四川大学学术委员会委员，四川大学学位委员会委员，中国化学会有机化学学科委员，四川大学教授、博士生导师，现任教育部绿色化学与技术重点实验室副主任。

    1981-1988 兰州大学化学系有机化学专业学习，分获理学学士学位和理学硕士学位。

    1993-1996 中国科学院化学研究所学习，获理学博士学位。

    1988-1993 西南师范大学化学系从事有机化学教学和科研工作，历任助教和副教授。

    1996-1997 中国科学院成都有机化学研究所从事不对称催化反应研究，历任副研究员和研究员，不对称合成联合开放实验室副主任，于1999被评聘为博士生导师。

    1998-1999 美国Colorado State University化学系做博士后研究。

    2000- 四川大学化学学院教授，博士生导师，四川大学学术委员会委员，四川大学学位委员会委员，中国化学会有机化学学科委员，绿色化学与技术教育部重点实验室副主任。

Prof. Dr. Xiaoming Feng

   Xiaoming Feng was born in Sichuan, China in 1964. Between 1981 and 1988, he studied chemistry at Lanzhou University. He received his BS in 1985 and MS in 1988 from the same university. Then he became an associate professor at Southwest Normal University in 1991 until 1993. In 1996, he received his PhD from Chinese Academy of Sciences under supervision of Professors Zhitang Huang and Yaozhong Jiang. He went to the Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences (1996–2000), and was appointed as a professor in 1997. After his postdoctoral research at Colorado State University (1998-1999) with Professor Yian Shi. He went back to Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences as a professor (1999-2000). In 2000, he moved to Sichuan University as a professor on the development of catalysts for asymmetric catalytic reactions and method of total synthesis for natural product.

Interested Research Areas: asymmetric synthesis; synthesis of heterocyclic compounds

Awards and Honors

  The Special Professor of the Chang Jiang Scholars by the Ministry of Education of China
  An award of the National Science Fund for Distinguished Young Scholars
  Research Award, by Trans-Century Training Programme Foundation for the Talents by the Ministry of Education of China

Course Taught

  asymmetric synthesis; chirotechnology; organic stereochemistry

    从事不对称合成方法学及手性医药、农药和具有生理活性化合物的合成研究。

    1. 新型催化剂的设计和合成及催化有机化学反应研究，国家自然科学基金重点项目（基金批准号：20732003），2008-2011，正在进行。

    2. 催化不对称多组分反应在手性C-N键形成中的应用研究， 国家自然科学基金项目（基金批准号：20872097），2009-2011，正在进行。

    3. 新型含氮双功能手性催化剂催化羰基化合物膦酰氢化反应研究，国家自然科学基金项目（基金批准号：20872096），2009-2011，正在进行。

    4. 新型双中心催化剂催化酮的不对称Henry反应研究，国家自然科学基金项目（基金批准号：20702033），2008-2010，正在进行。

    5. 手性有机酸盐催化酮的不对称腈化反应研究，国家自然科学基金项目（基金批准号：20602025），2007-2009，正在进行。

    6. 催化不对称α，β-不饱和羰基化合物的氧杂麦克尔反应研究，教育部博士点基金（基金批准号：20070610019），2008-2010，正在进行。

    7. 手性与手性药物研究中的若干科学问题研究，国家自然科学基金“十五”重大项目（基金批准号：20390055），2003-2007，已结题。

    8. 国家杰出青年科学基金，国家自然科学基金项目（基金批准号：20225206），2003-2006，已结题。

    9. 含氮氧偶极的手性催化剂催化醛与Brassard二烯的Hetero-Diels-Alder反应研究，国家自然科学基金项目（基金批准号：20472056），2005-2007，已结题。

    10. 产生手性原因的基本问题研究，教育部科学技术研究重点项目（基金批准号：104209），2004-2006，已结题。

    11. 新型手性氮氧偶极双功能催化剂催化酮的不对称硅腈化反应研究，国家自然科学基金项目（基金批准号：20372050），2004-2006，已结题。

    12. 企业合作项目。

    根据分子设计、分子识别等概念设计、合成了多系列新的手性催化剂，并用于醛、酮、亚胺的腈化反应，杂-Diels-Alder反应，Henry反应，Michael反应，动力学拆分以及硫醚氧化成亚砜等反应研究，均获得了高的分离产率和高的对映选择性，深入研究了这些反应的催化机理，发现非共价等弱相互作用对反应活性和对映选择性有巨大影响。首次将氮氧偶极作为Lewis碱引入到醛、酮和亚胺的腈化反应中，取得了高的催化活性和高的对映选择性；同时发展出的氮氧双功能有机催化剂和金属络合物催化剂在腈化反应、Henry反应，Michael反应，羰基-ene反应和烯丙基化反应等研究中，都获得了好的结果；在手性双功能催化剂的基础上，创新性地发展了新的双活化催化剂体系，为筛选高效、价廉、易得的催化剂发展了实用的方法；尤其是发现了催化量的苯甘氨酸钠能催化酮的硅腈化反应，获得了大于90%的收率和高达97% ee的对映选择性；我们发展了手性Lewis酸催化的Hetero-Diels-Alder反应，设计合成的催化剂对大多数的底物都能获得大于90% ee以上的对映选择性，为制备光学活性二氢吡喃酮和δ-内酯发展了不对称合成方法，用此方法一步合成了天然产物(R)-(+)-Hepialone，其收率达88%, 对映选择性达94% ee。将基础研究成果应用到绿色农药手性甲霜灵的合成中取得了成功，申请了中国发明专利。现已分别在J. Am. Chem. Soc., Angew. Chem. Int. Ed.，Chem. Eur. J., J. Org. Chem., Org. Lett., Adv. Synth. Catal., Tetrahedron, Synlett等刊物上发表论文100多篇，其中J. Org. Chem., 2002, 67, 2275-82这篇论文，被美国化学会的 Chemical Reseach News中Heart Cut收录，并对此作了专门的正面评论, J. Am. Chem. Soc., 2005, 127, 12224-5这篇论文入选了J. Am. Chem. Soc. 2005年7至9月的Most Accessed Articles(共20篇论文)，Angew. Chem. Int. Ed. 2007, 46，8468-70被评为该刊物的VIP论文，Angew. Chem. Int. Ed. 2008, 47, 1308-11被英国皇家化学会的Chemistry World进行了详细介绍和正面评价，J. Org. Chem. 2007, 72, 7715-19被评为该刊物的2007年7至9月的Most Accessed Article； J. Org. Chem. 2007, 72, 204被评为该刊物2007年的Most Accessed Article。多篇论文被评述性论文正面评述，多次被邀请在国际、国内会议上做邀请报告。作为主研人员获得2002年四川省科技进步壹等奖(排名第七)，2001年入选教育部《跨世纪优秀人才培养计划》，2002年获国家杰出青年科学基金资助，2004年获国务院政府特殊津贴， 2002年获四川省有突出贡献优秀专家称号， 2004年入选四川省学术与技术带头人，2005年入选教育部长江学者特聘教授，2007年入选人事部“新世纪百千万人才工程”国家级人选，2009年获全国优秀教师和四川省模范教师称号。

已发表论文100多篇,近年代表性论文目录如下(Selected Publications)：

1. Fei Wang, Xiaohua Liu, Yulong Zhang, Lili Lin and Xiaoming Feng*，Highly enantioselective synthesis of tertiary alcohols: C2-symmetric N,N`-dioxide-Sc(III) complex promoted direct aldol reaction of a-ketoesters and diazoacetate esters，Chem. Commun.,, 2009, 7297-9..

2. Xin Zhou, Yanling Liu, Lu Chang, Jiannan Zhao, Deju Shang, Xiaohua Liu, Lili Lin, Xiaoming Feng*, Highly Efficient Synthesis of Quaternary a-Hydroxy Phosphonates via Lewis Acid-Catalyzed Hydrophosphonylation of Ketones, Adv. Synth. Catal. 2009, 351, 2567-72.

3. Xuan He, Xin Cui, Maosi Li, Lili Lin, Xiaohua Liu, Xiaoming Feng*, Highly enantioselective fluorescent sensor for chiral recognition of amino acid derivatives, Tetrahedron Letts.,2009, 50, 5853-6.

4. Zhenhua Dong, Lijia Wang, Xiaohong Chen, Xiaohua Liu, Lili Lin, Xiaoming Feng*, Organocatalytic Enantioselective Michael Addition of 4-Hydroxycoumarin to α,β-Unsaturated Ketones: A Simple Synthesis of Warfarin, Eur. J. Org. Chem. 2009, 5192-7.

5. Jun Jiang, Xiaohong Chen, Jun Wang, Yonghai Hui, Xiaohua Liu, Lili Lin, Xiaoming Feng*, Chiral biphenylamide derivative: an efficient organocatalyst for the enantioselective synthesis of a-hydroxy phosphonates, Org. Biomol. Chem., 2009, 7, 4355-7.

6. Jie Liu, Zhigang Yang, Xiaohua Liu, Zhen Wang, Yanling Liu, Sha Bai, Lili Lin, Xiaoming Feng*, Organocatalyzed highly stereoselective Michael addition of ketones to alkylidene malonates and nitroolefins using chiral primary-secondary diamine catalysts based on bispidine, Org. Biomol. Chem., 2009, 7, 4120-7.

7. Jun Wang, Wentao Wang, Wei Li, Xiaolei Hu, Ke Shen, Cheng Tan, Xiaohua Liu, Xiaoming Feng*, Asymmetric Cyanation of Aldehydes, Ketones, Aldimines, and Ketimines Catalyzed by a Versatile Catalyst Generated from Cinchona Alkaloid, Achiral Substituted 2,2’-Biphenol and Tetraisopropyl Titanate, Chem. Eur. J., 2009, 15, 11642-59.

8. Xiaohua Liu, Lili Lin, Xiaoming Feng*, Amide Based Bifunctional Organocatalysts in Asymmetric Reactions (Feature Article), Chem. Commun.,, 2009, 6145-58.

9. Yonghai Hui, Qi Zhang, Jun Jiang, Lili Lin, Xiaohua Liu, Xiaoming Feng*, Highly Efficient Asymmetric Synthesis of 3-Indolyl(hydroxy)acetates via Friedel-Crafts Alkylation of Indoles, J. Org. Chem., 2009, 74, 6878-80.

10. Jian Shi, Min Wang, Ling He, Ke Zheng, Xiaohua Liu, Lili Lin, Xiaoming Feng*，Enantioselective Michael addition of malononitrile to chalcones catalyzed by a simple quinine–Al(OiPr)3 complex: a simple method for the synthesis of a chiral 4H-pyran derivative, Chem. Commun., 2009, 4711-3.

11. Donghui Chen, Zhenling Chen, Xiao Xiao, Zhigang Yang, Lili Lin, Xiaohua Liu, Xiaoming Feng*, Highly Enantioselective Michael Addition of Malonates to Enones Catalyzed by N,N'-Dioxide-Scandium(III) Complex, Chem. Eur. J., 2009, 6807-10.

12. Zhipeng Yu, Xiaohua Liu, Lin Zhou, Lili Lin, Xiaoming Feng*, Bifunctional Guanidine via an Amino Amide Skeleton for Asymmetric Michael Reactions of b-Ketoesters with Nitroolefins: A Concise Synthesis of Bicyclic b-Amino Acids, Angew. Chem. Int. Ed., 2009, 48, 5195-8.

13. Wentao Wang, Ke Shen, Xiaolei Hu, Jun Jiang, Xiaohua Liu, Xiaoming Feng*, Highly Enantioselective Synthesis of α–Diazo-β-Hydroxy Esters Using a Bifunctional Titanium Complex, Synlett, 2009, 1655-8.

14. Xiaolei Hu, Jun Wang, Wei Li, Lili Lin, Xiaohua Liu, Xiaoming Feng *，Cinchona alkaloid-derived quaternary ammonium salt combined with NaH: a facile catalyst system for the asymmetric trifluoromethylation of ketones，Tetrahedron Letts.,2009, 50, 4378-80.

15. Ke Shen, Xiaohua Liu, Yunfei Cai, Lili Lin, and Xiaoming Feng*，Facile and Efficient Enantioselective Strecker Reaction of Ketimines by Chiral Sodium Phosphate，Chem. Eur. J., 2009, 15, 6008-14.

16. Shikui Chen, Zongrui Hou, Yin Zhu, Jing Wang, Lili Lin, Xiaohua Liu, Xiaoming Feng*, Highly Enantioselective One-Pot, Three-Component Mannich-type Reaction Catalyzed by N,N'-Dioxide-Scandium(III) Complex, Chem. Eur. J., 2009, 15, 5884-7.

17. Xin Zhou, Deju Shang, Qi Zhang, Lili Lin, Xiaohua Liu, Xiaoming Feng*, Enantioselective Three-Component Kabachnik-Fields Reaction Catalyzed by Chiral Scandium(III)-N,N’-Dioxide Complexes, Organ. Lett., 2009, 11, 1401-4.

18. Deju Shang, Yanling Liu, Xin Zhou, Xiaohua Liu, Xiaoming Feng*, N,N'-Dioxide-Copper(II) Complex as Efficient Catalyst for Enantioselective and Diastereoselective Mannich-Type Reaction of Glycine Schiff Base with Aldimines, Chem. Eur. J., 2009, 15, 3678-81.

19. Yanling Liu, Deju Shang, Xin Zhou, Xiaohua Liu, Xiaoming Feng*, Enantioselective Friedel-Crafts Alkylation of Indoles with Alkylidene Malonates Catalyzed by N,N'-Dioxide-Scandium(III) Complexes: Asymmetric Synthesis of β-carbolines, Chem. Eur. J., 2009, 15, 2055-8.

20. Fei Wang, Xiaohua Liu, Yan Xiong, Xin Zhou, Xiaoming Feng*, Asymmetric Hydrophosphonylation of α-Ketoesters Catalyzed by Cinchona-derived Thiourea Organocatalyst, Chem. Eur. J., 2009, 15, 589-92.

21. Xiaohong Chen, Jun Wang, Yin Zhu, Deju Shang, Bo Gao, Xiaohua Liu, Xiaoming Feng,* Zhishan Su, Changwei Hu*，Secondary Amine Amide Organocatalyst for the Asymmetric Nitroaldol Reaction of alpha-Ketophosphonates，Chem. Eur. J., 2008, 14, 10896-9.

22. Cheng Tan, Xiaohua Liu, Liwei Wang, Jun Wang, Xiaoming Feng*, Highly Enantioselective Aza-Henry Reaction of Ketoimines Catalyzed by Chiral N,N’-Dioxide-Copper(I) Complexes, Org. Lett., 2008, 10，5305-8.

23. Ke Zheng, Jian Shi, Xiaohua Liu, Xiaoming Feng*, Asymmetric Carbonyl-Ene Reaction Catalyzed by Chiral N,N'-Dioxide-Nickel(II) Complex: Remarkably Broad Substrate Scope, J. Am. Chem. Soc., 2008, 130, 15770–1.

24. Lijia Wang, Xiaohua Liu, Zhenhua Dong, Xuan Fu, Xiaoming Feng*, Asymmetric Intramolecular Oxa-Michael Addition of Activated α,β-Unsaturated Ketones Catalyzed by Chiral N,N'-Dioxide-NiII Complex: Highly Enantioselective Synthesis of Flavanones, Angew. Chem. Int. Ed., 2008, 47, 8670-3.

25. Zhigang Yang, Jie Liu, Xiaohua Liu, Zhen Wang, Xiaoming Feng*, Zhishan Su, Changwei Hu*, Highly Efficient Amine Organocatalysts Based on Bispidine for the Asymmetric Michael Addition of Ketones to Nitroolefins, Adv. Synth. Catal., 2008, 350, 2001-6.

26. Lu Chang, Deju Shang, Junguo Xin, Xiaohua Liu, Xiaoming Feng*，Chiral N,N`-dioxide-iron(II) complexes catalyzed enantioselective oxa-Michael addition of α,β--unsaturated aldehydes，Tetrahedron Lett., 2008, 49, 6663-6.

27. Xu Yang, Xin Zhou, Lili Lin, Lu Chang, Xiaohua Liu, Xiaoming Feng*, Highly Enantioselective Direct Michael Addition of Nitroalkanes to Nitroolefins Catalyzed by La(OTf)3/N,N′-Dioxide Complexes, Angew. Chem. Int. Ed., 2008, 47, 7079-81.

28. Liwei Wang, Cheng Tan, Xiaohua Liu, Xiaoming Feng*，Aza-Henry Reaction of Ketoimines Catalyzed by Na2CO3: An Efficient Way to β-Nitroamines, Synlett, 2008, 2075-7.

29. Yuehong Wen, Bo Gao, Yngzi Fu, Shunxi Dong, Xiaohua Liu, Xiaoming Feng*, Asymmetric Three-Component Strecker Reactions Catalyzed by Trans-4-Hydroxy-L-Proline-Derived N,N'-Dioxides, Chem., Eur., J., 2008, 14，6789-95.

30. Xing Li, Xiaohua Liu, Yingzi Fu, Lijia Wang, Lin Zhou, Xiaoming Feng*, Direct Allylation of Aldimines Catalyzed by C2-Symmetric N,N’-Dioxide–ScIII Complexes: Highly Enantioselective Synthesis of Homoallylic Amines, Chem., Eur., J., 2008, 14，4796-8.

31. Zongrui Hou, Jun Wang, Xiaohua Liu, Xiaoming Feng*, Highly Enantioselective Strecker Reaction of Ketoimines Catalyzed by an Organocatalyst from (S)-BINOL and L-Prolinamide, Chem., Eur., J., 2008, 14，4484-6.

32. Jie Liu, Zhigang Yang, Zhen Wang, Fei Wang, Xiaohong Chen, Xiaohua Liu, Xiaoming Feng,* Zhishan Su, Changwei Hu,* Asymmetric Direct Aldol Reaction of Functionalized Ketones Catalyzed by Amine Organocatalysts Based on Bispidine, J. Am. Chem. Soc., 2008, 130, 5664-5.

33. Junguo Xin, Lu Chang, Zongrui Hou, Deju Shang, Xiaohua Liu, Xiaoming Feng*，An Enantioselective Biginelli Reaction Catalyzed by a Simple Chiral Secondary Amine and Achiral Brosted Acid by a Dual-Activation Route, Chem., Eur., J., 2008, 14, 3177-83.

34. Lili Lin, Zhenling Chen, Xu Yang, Xiaohua Liu, Xiaoming Feng*, Efficient Enantioselective Hetero-Diels-Alder Reaction of Brassard’s Diene with Aliphatic Aldehydes: A One-Step Synthesis of (R)-(+)-Kavain and (S)-(+)-Dihydrokavain, Org. Lett., 2008, 10, 1311-4.

35. Bo Gao, Yuehong Wen, Zhigang Yang, Xiao Huang, Xiaohua Liu, Xiaoming Feng*, Asymmetric Ring Opening of meso-Epoxides with Aromatic Amines Catalyzed by a New Proline-Based N,N’-Dioxide-Indium Tris(triflate) Complex, Adv. Synth. Catal., 2008, 350, 385-90.

36. Jinlun Huang, Jin Wang, Xiaohong Chen, Yuehong Wen, Xiaohua Liu, Xiaoming Feng*, Highly Enantioselective Allylation of Aromatic α-Keto Phosponates Catalyzed by Chiral N,N'-Dioxide-Indium(III) Complexes，Adv. Synth. Catal., 2008, 350, 287-94.

37. Shaohua Gou, Xin Zhou, Jun Wang, Xiaohua Liu, Xiaoming Feng*, Asymmetric hydrophosphonylation of aldehydes catalyzed by BINOL-containing nitrogen Al(III) complexes，Tetrahedron，2008，64，2664-70。

38. Zhipeng Yu, Xiaohua Liu, Zhenhua Dong, Mingsheng Xie, Xiaoming Feng*, Highly Effective N,N'-Dioxide-In(OTf)3 Complex for the Asymmetric Hetero-Diels-Alder Reaction of Danishefsky's Dienes and Aldehydes: An Application in Concise Total Synthesis of Triketide, Angew. Chem. Int. Ed., 2008, 47, 1308-11.

39. Xin Zhou, Xiaohua Liu, Xu Yang, Deju Shang, Junguo Xin, Xiaoming Feng*, Highly Enantioselective Hydrophosphonylation of Aldehydes Catalyzed by Tridentate Schiff Base-Aluminum(III) Complexes，Angew. Chem. Int. Ed., 2008, 47, 392-4.

40. Deju Shang, Junguo Xin, Yanling Liu, Xin Zhou, Xiaohua Liu, Xiaoming Feng*, Enantioselective Aza-Diels-Alder Reaction of Aldimines with “Danishefsky Type Diene” Catalyzed by Chiral Scandium(III)- N,N’-Dioxide Complexes, J. Org. Chem., 2008, 73，630-7.

41. Yan Xiong, Fei Wang, Shunxi Dong, Xiaohua Liu, Xiaoming Feng*, Bisprolinamide-Catalyzed Cross-Aldol Reaction of Aldehydes, Synlett, 2008, 73-5.

42. Ke Shen, Xiaohua Liu, Qinghan Li，Xiaoming Feng*，Highly enantioselective cyanosilylation of ketones catalyzed by a bifunctional Ti(IV) complex，Tetrahedron，2008, 64, 147-53.

43. Jun Wang, Xiaolei Hu, Jun Jiang, Shaohua, Xiao Huang, Xiaohua Liu, Xiaoming Feng*, Asymmetric Activation of tropos 2,2`-Biphenol with Cinchonine Generating a Remarkably Effective Catalyst for the Asymmetric Strecker Reaction of N-Ts Protected Aldimines and Ketoimines, Angew. Chem. Int. Ed., 2007, 46, 8468-70.

44. Hui Zhou, Dan Peng, Bo Qin, Zongrui Hou, Xiaohua Liu, Xiaoming Feng*, Highly Enantioselectivity Aza-Henry Reaction of N-Tosyl Imines Catalyzed by N,N’-Dioxide-Cu(I) Complexes, J. Org. Chem., 2007, 72，10302-4.

45. Fei Wang, Yan Xiong, Xiaohua Liu, Xiaoming Feng*, Asymmetric Direct Aldol Reaction of α-Keto Esters and Acetone Catalyzed by Bifunctional Organocatalysts, Adv. Synth. Catal., 2007, 349, 2665-8.

46. Bo Qin, Xiao Xiao, Xiaohua Liu, Jinlun Huang, Yuehong Wen, Xiaoming Feng*, Highly Enantioselective Henry (Nitroaldol) Reaction of Aldehydes and ?-Ketoesters Catalyzed by N,N’-dioxide-Copper(I) Complexes, J. Org. Chem., 2007, 72, 9323-8.

47. Ke Zeng, Bo Qin, Xiaohua Liu, Xiaoming Feng*, Highly Enantioselective Allylation of α-Ketoesters Catalyzed by N,N'-Dioxide-In(III) Complexes, J. Org. Chem., 2007, 72, 8478-83.

48. Yuehong Wen, Yan Xiong, Lu Chang, Jinglun Huang, Xiaohua Liu, Xiaoming Feng*, Chiral Bisformamides as Effective Organocatalysts for Asymmetric One-pot, Three-Component Strecker Reaction, J. Org. Chem., 2007, 72, 7715-19.

49. Wentao Wang, Saohua Gou, Xiaohua Liu, Xiaoming Feng*, Catalytic Asymmetric Cyanoethoxycarbonylation of Aldehydes Using Self-Assembled Titanium Catalysts, Synlett, 2007, 2875-8.

50. Dan Peng, Hui Zhou, Xiaohua Liu, Liwei Wang, Shikui Chen, Xiaoming Feng*, Enantioselective Cyanoformylation of Aldehydes Catalyzed by a Chiral Quaternary Ammonium Salt and Triethylamine, Synlett, 2007, 2448-50.

51. Yan Xiong, Yuehong Wen, Fei Wang, Bo Gao, Xiaohua Liu, Xiao Huang, Xiaoming Feng*, A Chiral Functionalized Salt-Catalyzed Asymmetric Michael Addition of Ketones to Nitroolefines, Adv. Synth. Catal., 2007, 349, 2156-66.

52. Lili Lin, Xiaohua Liu, Xiaoming Feng*, Asymmetric Hetero-Diels_alser Reactions of Danishefsky`s and Brassard`s Dienes with Aldehydes, Synlett(account), 2007, 2147-57.

53. Shaohua Gou, Xiaohua Liu, Xin Zhou, Xiaoming Feng*, Asymmetric Cyano-Ethoxycarbonylation of Aldehydes Catalyzed by Self-Assembled Titanium Catalyst, Tetrahedron, 2007, 63, 7935-41.

54. Xin Zhang, Donghui Chen, Xiaohua Liu, Xiaoming Feng*, Enantioselective Allylation of Ketones Catalyzed by N,N`-Dioxide and Indium(III) Complex, J. Org. Chem., 2007, 72, 5227-33.

55. Haitao Zhao, Bo Qin, Xiaohua Liu, Xiaoming Feng*, Enantioselective Trifluoromethylation of Aromatic Aldehydes Catalyzed by Combinatorial Catalysts, Tetrahedron, 2007, 63, 6822-6.

56. Baiqing Zeng, Xin Zhou, Xiaohua Liu, Xiaoming Feng*, Enantioselective Cyanosilylation of Aldehydes Catalyzed by a Novel N,N`-Dioxide–Ti(OiPr)4 Bifunctional Catalyst, Tetrahedron, 2007, 63, 5129-36.

57. Bo Qin, Xiaohua Liu., Jian Shi, Ke Zheng, Haitao Zhao, Xiaoming Feng*, Enantioselective Cyanosilylation of ?,?-Dialkoxy Ketones Catalyzed by Proline-Derived in Situ Prepared N-Oxides as Bifunctional Organocatalysts, J. Org. Chem., 2007, 72, 2374-8.

58. Shaohua Gou, Jun Wang, Xiaohua Liu, Wentao Wang, Fuxue Chen, Xiaoming Feng*, Asymmetric Cyano-ethoxycarbonylation of Aldehydes Catalyzed by Heterobimetallic Aluminum Lithium Bis(binaphthoxide) and Cinchonine, Adv. Synth. Catal., 2007, 349, 343-9.

59. Jinglun Huang, Xiaohua Liu, Yuehong Wen, Bo Qin, Xiaoming Feng*, Enantioselective Strecker Reaction of Phosphinoyl Ketoimines Catalyzed by in situ Prepared Chiral N,N`-Dioxides, J. Org. Chem., 2007, 72，204-8.

60. Shikui Chen, Dan Peng, Hui Zhou, Liwei Wang, Fuxue Chen, Xiaoming Feng*, Highly Enantioselective Cyanation of Aldehydes Catalyzed by In Situ Salen-Ti(OiPr)4 Mononuclear Complex, Eur. J. Org. Chem., 2007, 639-44.

61. Yan Xiong, Fei Wang, Xiao Huang, Yuehong Wen, Xiaoming Feng*, A New Copper(I)- Tetrahydrosalen-Catalyzed Asymmetric Henry Reaction and Its Extending to Synthesis of (S)-Norphenylephrine, Chem. Eur. J., 2007, 13, 829-33.

62. Xiao Huang, Jinglun Huang, Yuehong Wen, Xiaoming Feng*, Asymmetric Strecker Reaction of Ketoimines Catalyzed by a Novel Chiral Bifunctional N,N`-Dioxide, Adv. Synth. Catal., 2006, 348, 2579-84.

63. Shaohua Gou, Xiaohong Chen, Yan Xiong, Xiaoming Feng*, Highly Enantioselective Cyanation of Aldehydes Catalyzed by a Multicomponent Titanium Complex, J. Org. Chem., 2006, 71, 5732-6.

64. Qinghan Li, Lu Chang, Xiaohua Liu, Xiaoming Feng*, Catalytic Asymmetric Cyano- Ethoxycarbonylation reaction of Aldehydes Using a Novel C2-Symmetric Chiral N,N`-Dioxide Titanium Complex, Synlett, 2006, 1675-8.

65. Lili Lin, Qian Fan, Bo Qin, Xiaoming Feng*, Highly Enantio- and Diastereoselective Brassard Type Hetero-Diels-Alder Approach to 5-Methyl-Containing α,β-Unsaturated δ-Lactones，J. Org. Chem., 2006, 71, 4141-6.

66. Qinghan Li, Xiaohua Liu, Jun Wang, Ke Shen, Xiaoming Feng*, Asymmetric Cyanosilylation of ketones catalyzed by Novel Chiral N,N`-Dioxide Titanium Complexes，Tetrahedron Letts.,2006, 47, 4011-4.

67. Yanling Liu, Xiaohua Liu, Junguo Xin, Xiaoming Feng*，Asymmetric Cyanosilylation of Aldehydes Catalyzed by Novel Chiral Tetraaza Titanium Complexes，Synlett, 2006, 1085-9.

68. Jie Liu，Xing Li，Jun Wang，Xiaoming Feng*, Highly Efficient Approach to 4-Ethoxy-5, 6-disubstituted Pyran-2-ones using a combinational Lewis Acid-Base System, Adv. Synth. Catal., 2006, 348, 939-44.

69. Yan Xiong, Xiao Huang, Shaohua Gou, Jinglun Huang, Yuehong Wen, Xiaoming Feng*, Enantioselective cyanosilylation of ketones catalyzed by a nitrogen-containing bifunctional catalyst, Adv. Synth. Catal., 2006, 348, 538-44.

70. Zhishan Su, Changwei Hu*, Song Qin, Xiaoming Feng*, A quantum chemical study on the mechanism of chiral N-oxides-catalyzed Strecker reaction, Tetrahedron, 2006, 62, 4071-80.

71. Lijia Wang, Xiao Huang, Jun Jiang, Xiaohua Liu, Xiaoming Feng*, Catalytic cyanosilylation of ketones using organic catalyst 1,1,3,3-tetramethylguanidine, Tetrahedron Letts.,2006, 47, 15581-4.

72. Bo Gao, Zhipeng Yu, Zhengyan Fu, Xiaoming Feng*, A convenient and versatile approach to 2,3-dihydro-4H-pyran-4-ones via tandem aldol reaction-conjuagate addition, Tetrahedron Letts.,2006, 47, 1537-9.

73. Fuxue Chen，Xiaoming Feng*，Asymmetric Synthesis of Cyanohydrins，Current Org. Synth., 2006, 3, 77-97.

74. Weiqing Yang, Deju Shang, Yanling Liu, Ying Du, Xiaoming Feng*, Highly Enantioselective Synthesis of 2, 6-Disubstituted and 2, 2, 6-Trisubstituted Dihydropyrones: A One-Step Synthesis of (R)-(+)-Hepialone and its Analogues, J. Org.. Chem., 2005, 70, 8533-7.

75. Yuehong Wen, Xiao Huang, Jinglun Huang, Yan Xiong, Bo Qin, Xiaoming Feng*, Asymmetric Cyanosilylation of Aldehydes Catalyzed by Novel Organocatalysts, Synlett, 2005, 2445-8.

76. Xiaohua Liu, Bo Qin, Bin He, and Xiaoming Feng*，Catalytic Asymmetric Cyanosilylation of Ketones by a Chiral Amino Acid Salt，J. Am. Chem. Soc., 2005, 127, 12224-5.

77. Ke Cheng, Lili Lin, Shikui Chen, Xiaoming Feng*, A Mild and Efficient Aza-Diels-Alder Reaction of N-benzhydryl Imines With trans-1-Methoxy-2-Methyl-3- Trimethylsiloxybuta-1,3-Diene Catalyzed by Yb(OTf)3, Tetrahedron, 2005, 61, 9594-9.

78. Qian Fan, Lili Lin, Jie Liu, Yaozong Huang, Xiaoming Feng*， A Mild and Efficient Asymmetric Hetero-Diels-Alder Reaction of Brassard Diene with Aldehydes，Eur. J. Org. Chem.，2005，3542-52.

79. Daijun Xiao, Lijia Wang, Xiaoming Feng*，A Practical Synthetic Pathway to Multi-substituted Tetrahydropyridines via Multicomponent Reactions Catalyzed by BF3??Et2O，Synlett，2005，1531-4.

80. Bo Gao，Zhengyan Fu, Zhipeng Yu, Lan Yu, Yaozhong Huang, Xiaoming Feng*，Highly Efficient Enantioselective Hetero-Diels-Alder Reaction between trans-1-Methoxy-2-methyl-3- trimethylsiloxybuta-1,3-diene and Aldehydes Catalyzed by (R)-BINOL－Ti(IV) Complex, Tetrahedron, 2005, 61, 5822-30.

81. Ke Cheng, Baiqing Zeng, Zhipeng Yu, Bo Gao, Xiaoming Feng?, A Mild and Efficient Synthesis of 2,5-Disubstituted 2,3-Dihydro-4-Pyridones Catalyzed by Yb(OTf)3, Synlett, 2005, 1018-20.

82. Fu-Xue Chen, Xiaoming Feng*, Synthesis of Racemic Tertiary Cyanohydrins, Synlett, 2005, 892-9.

83. Bin He, Fu-Xue Chen, Yan Li, Xiaoming Feng*, Guolin Zhang, Effective Activation of Chiral Salen/Ti(OiPr)4 Catalyst with Achiral Phenolic N-Oxides as Additives in the Enantioselective Cyanosilylation of Ketones，Eur. J. Org. Chem., 2004, 4657-66.

84. Yan Li， Bin He， Bo Qin， Xiaoming Feng*， Guolin Zhang，Highly Enantioselective Cyanosilylation of Aldehydes Catalyzed by Novel β-Amino Alcohol-Titanium Complexes，J. Org. Chem.， 2004，69，7910-3.

85. Fu-Xue Chen, Hui Zhou， Xiaohua Liu，Bo Qin, Xiaoming Feng*, Guolin Zhang, Yaozhong Jiang, Enantioselective cyanosilylation of ketones by a catalytic double-activation method using aluminum complex and N-oxide, Chem. Eur. J., 2004, 10，4790-7。

86. Fu-Xue Chen, Bo Qin, Xiaoming Feng*, Guolin Zhang, Yaozhong Jiang, Enantioselective cyanosilylation of ketones catalyzed by double-activation catalysts with N-oxides, Tetrahedron( symposium in print), 2004, 60, 10049-60.

87. Fu-Xue Chen, Xiaohua Liu, Bo Qin, Hui Zhou, Xiaoming Feng*, Guolin Zhang, Highly Efficient Double-Activation Catalysts for the Synthesis of Ketone Cyanohydrins, Synthesis, 2004, 2266-72.

88. Bin He, Yan Li, Xiaoming Feng*, Guolin Zhang, Inorganic/Organic salt as heterogeneous basic catalysts for cyanosilylation of carbonyl compounds, Synlett, 2004, 1776-8.

89. Bin He, Fu-Xue Chen, Yan Li, Xiaoming Feng*, Guolin Zhang, Achiral phenolic N-oxides as additives: an alternative strategy for asymmetric cyanosilylation of ketones, Tetrahedron Letts.,2004, 45, 5465-7.

90. Zhengyan Fu, Bo Gao, Zhipeng Yu, Lan Yu, Yaozhong Huang, Xiaoming Feng*, Guolin Zhang, An Efficient and Enantioselective Approach to 2,5-Disubstituted Dihydropyrones, Synlett, 2004, 1772-5.

91. Yan Li, Bin He, Xiaoming Feng*, Guolin Zhang, Phenolic N-oxide as a Highly Efficient Organocatalyst for Cyanosilylation of Ketones, Synlett, 2004, 1598-600.

92. Qian Fan, Lili Lin, Jie Liu, Yaozong, Xiaoming Feng*, Guolin Zhang, Highly Enantioselective Hetero-Diels-Alder Reaction of Brassard Diene with Aromatic Aldehydes, Org. Lett., 2004, 6, 2185-8.

93. Hui Zhou, Fu-Xue Chen, Bo Qin, Xiaoming Feng*, Guolin Zhang, Cyanosilylation of Ketones Catalyzed by Quaternary Ammonium Salt and N-oxide, Synlett, 2004, 1077-9.

94. Yongcun Shen, Xiaoming Feng*, Yan Li, Guolin Zhang, Yaozhong Jiang, Asymmetric cyanosilylation of krtones catalyzed by bifunctional chiral N-oxide titanium complex catalysts, Eur J. Org. Chem., 2004, 129-37.

95. Zhigang Jiao, Xiaoming Feng*, Bo Liu, Fuxue Chen, Guolin Zhang, Yaozhong Jiang, Enantioselective strecker reaction of aldimines and trimethylsilyl cyanide promoted by chiral N,N’-dioxide，Eur J. Org. Chem., 2003, 3818-26.

96. Yongcun Shen, Xiaoming Feng*, Yan Li, Guolin Zhang, Yaozhong Jiang, A mild and efficient cyanosilylation of ketones catalyzed by a Lewis acid-Lewis base bifunctional catalyst, Tetrahedron, 2003, 59, 5667-75.

97. Fuxue Chen, Xiaoming Feng*, Bo Qin, Guolin Zhang, Yaozhong Jiang, Highly Efficient Silylcyanation of Ketones by a Catalytic Double Activation Method Using Lewis Acid and N-Oxide Catalysts, Synlett, 2003, 558-60.

98. Fuxue Chen, Xiaoming Feng*, Bo Qin, Guolin Zhang, Yaozhong Jiang, Enantioselective cyanosilation of ketones by a catalytic double activation method employing chiral Lewis acid and achiral N-oxide catalysts, Org. Lett., 2003, 5, 949-52.

99. Yaozong Huang, Xiaoming Feng*, Bin Wang, Guolin Zhang, Yaozhong Jiang, Catalytic Enantioselective Synthesis of 2,6-Disubstituted Dihydropyrones by Hetero-Diels-Alder Reaction Using Chiral Binol-Ti(IV) complex, Synlett, 2002, 2122-4.

100. Yongcun Shen, Xiaoming Feng*, Guolin Zhang, Yaozhong Jiang; Asymmetric Cyanosilylation of Ketones Catalyzed by Chiral N-oxide-Titanium Complex, Synlett, 2002, 1353-5.

101. Yongcun Shen, Xiaoming Feng*, Yan Li, Guolin Zhang, Yaozhong Jiang, A Mild and Efficient Cyanosilylation of Ketones Using in situ Generated N-oxides-Ti(OiPr) Complexes as Catalysts. Synlett, 2002, 793-5.

102. Bin Wang, Xiaoming Feng*, Yaozong Huang, Hui Liu, Xin Cui, Yaozhong Jiang, A Highly Enantioselective Hetero-Diels-Alder Reaction of Aldehydes with Danishefsky`s Diene Catalyzed by Chiral Titanium(IV) (5,5’6,6’7,7’8,8’-Octahydro-1,1’-Bi-2-Naphthol) Complexes, J. Org. Chem., 2002, 67, 2175-82.

103. Xiaoming Feng, Lianhe Shu, Yian Sh*, Chiral Lewis Acid Catalyzed Resolution of Racemic Enol Ester Epoxides. Conversion of Both Enantiomers of an Enol Ester Epoxide to the Same Enantiomer of a-Acyloxy Ketones, J. Org. Chem., 2002, 67, 2831-6.

104. Bo Liu, Xiaoming Feng*, Fuxue Chen, Guolin Zhang, Xin Cui, Yaozhong Jiang, Enantioselective Strecker Reaction Promoted by Chiral Lewis Bases, Synlett., 2001, 1551-4.

105. Yungui Peng, Xiaoming Feng*, Kaibai Yu, Zhi Li,Yaozhong Jiang, Chi-Hung Yeung, Synthesis and Crystal Structure of Bis[(4S,5S)-4,5-dihydro-4,5-diphenyl-2-(2’-oxidophenyl-cO)Oxazole-cN] Copper(II) and Its Application in the Asymmetric Baeyer-Villiger Reaction, J. Organomet. Chem., 2001, 619(1-2), 204-8.

106. Bin Wang, Xiaoming Feng*, Xin Cui, Hui Liu, Yaozhong Jiang, Highly efficient enantioselective synthesis of optically active dihydropyrones by chiral Titanium(IV) (5,5’,6,6’,7,7’,8,8’-octahydro-1,1’-bi-2-naphthol) complexes, Chem. Commun., 2000, (17), 1605-6.

107. Xiaoming Feng, Lianhe Shu, Yian Shi*, Complete Conversion of Racemic Enol Ester Epoxides into Optically Active a-Acyloxy Ketones, J. Am. Chem. Soc., 1999, 121, 11002-3.