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杨 成
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2012年9月-                    教授 四川大学 化学学院

2008年10月-2012年3月    先驱研究员(PRESTO,兼任) 光物质作用领域 (JST)

2007年6月-2012年8月     助理教授, 大阪大学

2004年6月- 2007年5月    研究员, 日本科学技术振兴机构

2000年10月- 2004年3月   博士 (国费留学生) 长崎大学药学院

1998年9月- 2000年8月    助教 浙江大学药学院

1991年9月-1998年7月     学士及硕士 四川大学化学系

主要研究方向

“手性光化学反应;大环超分子光化学;主客体作用;分子光化学与光物理;光子能量上转换等。”

1. 发展了超分子科学在手性光化学领域里的应用: (1) 揭示了超分子主体分子结构, 外部环境因素的特殊效应。(2)建立了多重超分子控制手性光化学的方法,使反应获得了98%产率和99%ee的高选择性。(3)首次实现了非敏化手性光催化。

2. 首次证明了波长效应对光化学反应立体选择性的关键作用.

3. 构建了具有超强包接力的主客体作用体系: (1)发现CB[7]可以与氨基二茂铁衍生物形成结合能为3Í1015 M-1超强络合物。(2)证实基于金刚烷和双环[2.2.2]辛烷的客体分子和CB[7]的包接不遵守焓熵补偿原理,获得5Í1015 M-1这一人工超分子体系中最高的包接常数。

主要工作业绩

2000年-2004年 日本文部省国费奖学金

2005年  亚太环糊精学会 Nagai Semi-excellent奖

2008 年-2012年 日本科学技术振兴机构 先驱学者(PRESTO Researcher)

2012年 亚洲大洋洲光化学协会 青年科学家奖

2012年 中组部第7批”千人计划”青年项目入选

课题组主页: www.yangchenggroup.com

代表性成果 (获奖成果、专著、论文、专利)
2017
[4]   Temperature-Driven Planar Chirality Switching of a Pillar[5]arene-Based Molecular Universal Joint, Jiabin Yao +, Wanhua Wu +, Wenting Liang, Yujun Feng, Dayang Zhou, Jason J. Chruma, Gaku Fukuhara, Tadashi Mori,Yoshihisa Inoue, and Cheng Yang*, Angew.Chem. Int.Ed. 2017, 56, 6869–6873. DOI:10.1002/anie.201702542

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[3]  Enantiodifferentiation in the Photoisomerization of (Z,Z)-1,3-Cyclooctadiene in the Cavity of γ-Cyclodextrin–Curcubit[6]uril-Wheeled [4]Rotaxanes with an Encapsulated Photosensitizer, Zhiqiang Yan, Qinfei Huang, Wenting Liang, Xingke Yu, Dayang Zhou, Wanhua Wu, Jason J. Chruma, and Cheng Yang*, Org. Lett.201719, 898–901. DOI: 10.1021/acs.orglett.7b00057

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[2]  Switched enantioselectivity by solvent components and temperature in photocyclodimerization of 2-anthracenecarboxylate with 6A,6X-diguanidio?γ-cyclodextrins, Jigao Yi, Wenting Liang, Xueqin Wei, Jiabin Yao, Zhiqiang Yan, Dan Sua, Zhihui Zhong, Guowei Gao, Wanhua Wu *, Cheng Yang*,  Chin. Chem. Lett. (In Press). DOI10.1016/j.cclet.2017.05.004
[1]   Photochirogenic nanosponges: phase-controlled enantiodifferentiating photoisomerization of (z)-cyclooctene sensitized by pyromellitate-crosslinked linear maltodextrin, Wenting Liang, Meiling Zhao, Xueqin Wei, Zhiqiang Yan,Wanhua Wu, Fabrizio Caldera, Francesco Trotta, * Yoshihisa Inoue, * Dan Su, Zhihui Zhong and Cheng Yang*, RSC Adv., 2017,7, 17184-17192 .  DOI:  10.1039/C6RA28211C

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2016
[8]  Fabrication of chiral-molecular@ nanoparticle complex materials with great chiroptical effect in visible region, Duan Xie, Yarong Su, Cheng Yang, Yidong Hou, Fuhua Gaoa, , Jinglei Dua, Jianhua Zhua *, Microelectronic Engineering , 2016,153, 24–28. DOI:org/10.1016/j.mee.2016.01.008
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[7]  Temporal analysis of blood–brain barrier disruption and cerebrospinal fluid matrix metalloproteinases in rhesus monkeys subjected to transient ischemic stroke, Yingqian Zhang, Feng Fan, Guojun Zeng, Linlin Zhou, Yinbing Zhang, Jie Zhang, He Jiao, Ting Zhang, Dan Su, Cheng Yang, Xin Wang, Kai Xiao, Hongxia Li, Zhihui Zhong*,  Journal of Cerebral Blood Flow & Metabolism, 2016,   DOI:  10.1177/0271678X16680221
[6]  Supramolecular Photochirogenesis with a Higher-Order Complex: Highly Accelerated Exclusively Head-to-Head Photocyclodimerization of 2-Anthracenecarboxylic Acid via 2:2 Complexation with Prolinol, Yuko Kawanami, Shin-ya Katsumata, Masaki Nishijima, Gaku Fukuhara, Kaori Asano, Takeyuki Suzuki, Cheng Yang, Asao Nakamura, Tadashi Mori, and Yoshihisa Inoue *J. Am. Chem. Soc. 2016, 138 (37), 12187–12201. DOI: 10.1021/jacs.6b05598
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[5]  Electrostatically promoted dynamic hybridization of glucans with cationic polythiophene,  Gaku Fukuhara, Mami Imai, Denis Fuentealba, Yuki Ishida, Hiroki Kurohara, Cheng Yang, Tadashi Mori, Hiroshi Uyama, Cornelia Bohne and Yoshihisa Inoue  *, Org. Biomol. Chem. , 2016, 14, 9741-9750.  DOI:  10.1039/C6OB01353H
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[4]  Enhanced Triplet–Triplet Energy Transfer and Upconversion Fluorescence through Host–Guest Complexation, Chunying Fan , Wanhua Wu , Jason J. Chruma , Jianzhang Zhao , and Cheng Yang*, J. Am. Chem. Soc.2016, 138 (47), 15405–15412. DOI:10.1021/jacs.6b07946
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[3]  Enantiodifferentiating [4 + 4] photocyclodimerization of 2-anthracenecarboxylate mediated by a self-assembled iron tetrahedral coordination cage, Mani Alagesan,  Kuppusamy Kanagaraj, Shigang Wan, Huiqin Sun, Dan Su, Zhihui Zhong, Dayang Zhou, Wanhua Wu, Guowei Gao, Hui Zhang, Cheng Yang*,  M. Alagesan et al. /Journal of Photochemistry and Photobiology A: Chemistry, 2016, 331 ,95–101.  DOI :10.1016/j.jphotochem.2015.10.023 
[2]  Enhanced head-to-head photodimers in the photocyclodimerization of anthracenecarboxylic acid with a cationic pillar[6]arene, Jian-Chang Gui 1, Zhi-Qiang Yan  1, Yuan Peng, Ji-Gao Yi, Da-Yang Zhou, Dan Su, Zhi-Hui Zhong, Guo-Wei Gao, Wan-Hua Wu, Cheng Yang *, Chinese Chemical Letters, 2016, 27, 1017–1021. DOI:org/10.1016/j.cclet.2016.04.021
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[1]  Inherently Chiral Azonia[6]helicene-Modified β-Cyclodextrin: Synthesis, Characterization, and Chirality Sensing of Underivatized Amino Acids in Water, Qinfei Huang, Liangwei Jiang, Wenting Liang, Jianchang Gui, Dingguo Xu, Wanhua Wu, Yoshito Nakai, Masaki Nishijima, Gaku Fukuhara, Tadashi Mori, Yoshihisa Inoue*, and Cheng Yang* , J. Org. Chem.201681, 3430–3434. DOI: 10.1021/acs.joc.6b00130
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2015
[ 3]  Recent advance of photochromic diarylethenes-containing supramolecular systems, Chao Xiao 1, Wei-Ye Zhao 1, Da-Yang Zhou, Yan Huang, Ye Tao, Wan-Hua Wu* , Cheng Yang*,  Chinese Chemical Letters, 2015, 26, 817–824. DOI: org/10.1016/j.cclet.2015.05.013
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[2] Catalytic Supramolecular Photochirogenesis, Zhiqiang Yan, Wanhua Wu, Cheng Yang, Yoshihisa Inoue*,  Supramolecular Catalysis, 2015, 2(1).  DOI: 10.1515/supcat-2015-0002
[1] Solvent- and Phase-Controlled Photochirogenesis. Enantiodifferentiating Photoisomerization of (Z)-Cyclooctene Sensitized by Cyclic Nigerosylnigerose-based Nanosponges Crosslinked by Pyromellitate, X. Wei, W. Liang, W. Wu, C. Yang *, F. Trotta, F. Caldera, A. Mele, T. Nishimoto, Y. Inoue *Org. Biomol. Chem, 2015, 13, 2905-2912.  DOI:10.1039/C4OB02390K
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2014
[5] 基于环糊精的超分子手性光化学反应 [J] 姚家斌,徐梦瑜,严志强,伍晚花,杨成 *有机化学 2014,1, 26-35. DOI:10.6023/cjoc201308038
[4]  Manipulating γ-cyclodextrin-mediated photocyclodimerization of anthracenecarboxylate by wavelength ,temperature,solvent and host, C. Yang*, Q. Wang, M. Yamauchi, J. Yao, D. Zhou, M. Nishijima, G. Fukuhara, T. Mori, Y. Liu * and Y. Inoue*,  Photochem. Photobiol. Sci., 2014, 13, 190-198.  DOI: 10.1039/C3PP50255D
[3]  Mammalian serum albumins as a chiral mediator library for bio-supramolecular photochirogenesis: optimizing enantiodifferentiating photocyclodimerization of 2-anthracenecarboxylate, M. Nishijima, M. Goto, M. Fujikawa, C. Yang, T. Mori, T. Wada and Y. Inoue *,   Chem. Commun.2014, 50, 14082-14085.  DOI: 10.1039/C4CC04818K
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[2]  Supramolecular Photochirogenesis, C. Yang*and Y. Inoue *Chem. Soc. Rev., 2014, 43, 4123--4143.  DOI: 10.1039/C3CS60339C
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[1]  Masaki Nishijima, Gaku Fukuhara,Tadashi Mori, and Yoshihisa Inoue*. Ammonia-Driven Chirality Inversion and Enhancement in Enantiodifferentiating Photocyclodimerization of 2- Anthracenecarboxylate Mediated by Diguanidino-γ-cyclodextrin, Jiabin Yao, Zhiqiang Yan, Jiecheng Ji, Wanhua Wu, Cheng Yang*,  J. Am. Chem. Soc., 2014, 136, 6916-6919. DOI: org/10.1021/ja5032908

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2013
[8]  Recent progress in supramolecular chiral photochemistry, Cheng Yang, Chin. Chem. Lett., 201324, 437-441. DOI: org/10.1016/j.cclet.2013.03.028
[7]  Diastereodifferentiating Photocyclodimerization of 2-Anthracenecarboxylates Tethered to a Cyclic Tetrasaccharide Scaffold: Critical Control of Photoreactivity and Stereoselectivity , G. Fukuhara *, T. Nakamura, Y. Kawanami,  C. Yang, T. Mori, H. Hiramatsu, Y. Dan-oh, T. Nishimoto, K. Tsujimoto and Y. Inoue *J. Org. Chem., 201378, 10996-11006.  DOI: 10.1021/jo401977f
[6]  Cross- versus Homo-Photocyclodimerization of Anthracene and 2-Anthracenecarboxylic Acid Mediated by a Chiral Hydrogen-Bonding Template. Factors Controlling the Cross-/Homo-Selectivity and Enantioselectivity , Y. Kawanami, H. Umehara, J.-i. Mizoguchi, M. Nishijima, G. Fukuhara,  C. Yang, T. Mori and Y. Inoue *, J. Org. Chem., 201378, 3073-3085. DOI: 10.1021/jo302818w

IMG_256
[5]  Phase-controlled supramolecular photochirogenesis in cyclodextrin nanosponges, W. Liang,  C. Yang *, D. Zhou, H. Haneoka, M. Nishijima, G. Fukuhara, T. Mori, F. Castiglione, A. Mele *, F. Caldera, F. Trotta *and Y. Inoue*. Chem. Commun. (Cambridge, U. K.), 201349, 3510-3512. DOI: 10.1039/c3cc40542g
[4]  Chiral recognition and supramolecular photoreaction of 1, 1′-binaphthol with bovine and human serum albumins , M. Nishijima, J.-W. Chang,  C. Yang, G. Fukuhara, T. Mori and Y. Inoue *Res. Chem. Intermed., 201339, 371-383. DOI: 10.1007/s11164-012-0655-1
[3]  Photochirogenesis with mutant human serum albumins: enantiodifferentiating photocyclodimerization of 2-anthracenecarboxylate,M. Nishijima, H. Kato, G. Fukuhara,  C. Yang, T. Mori, T. Maruyama, M. Otagiri * and Y. Inoue *, Chem. Commun. (Cambridge, U. K.), 201349, 7433-7435. DOI: 10.1039/c3cc42656d
[2]   Catalytic Bio-Supramolecular Photochirogenesis: Batch-Operated Enantiodifferentiating Photocyclodimerization of 2-Anthracenecarboxylate with Human Serum Albumin, M. Nishijima, H. Kato, C. Yang, G. Fukuhara, T. Mori, Y. Araki, T. Wada and Y. Inoue*, Chem Cat Chem, 2013, 5, 3237-3240. DOI: 10.1002/cctc.201300160.
[1]   Supramolecular photochirogenesis with functional amyloid superstructures, M. Nishijima, H. Tanaka,  C. Yang, G. Fukuhara, T. Mori, V. Babenko, W. Dzwolak *and Y. Inoue *, Chem. Commun. (Cambridge, U. K.), 201349, 8916-8918. DOI: 10.1039/c3cc44235g
2012
[7]   Strictly Diastereocontrolled Photocyclodimerization of 2-Anthracenecarboxylates Tethered to Cyclic Tetrasaccharide, G. Fukuhara*, T. Nakamura, Y. Kawanami,  C. Yang, T. Mori, H. Hiramatsu, Y. Dan-oh, K. Tsujimoto and Y. Inoue*,  Chem. Commun. (Cambridge, U. K.), 201248, 9156-9158. DOI: 10.1039/c2cc34880b
[6]  Enantiodifferentiating Photocyclodimerization of 2?Anthracenecarboxylic Acid via Competitive Binary/Ternary Hydrogen-Bonded Complexes with 4?Benzamidoprolinol,Y. Kawanami, S.-y. Katsumata, J.-i. Mizoguchi, M. Nishijima, G. Fukuhara,  C. Yang, T. Mori and Y. Inoue*,  Org. Lett., 201217, 4962-4965. DOI : 10.1021/ol3023402
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[5]  Cyclodextrin nanosponge-sensitized enantiodifferentiating photoisomerization of cyclooctene and 1,3-cyclooctadiene, W. Liang,  C. Yang*, M. Nishijima, G. Fukuhara, T. Mori, A. Mele*, F. Castiglione, F. Caldera, F. Trotta* and Y. Inoue*, Beilstein J. Org. Chem., 20128, 1305-1311. DOI: 10.3762/bjoc.8.149
[4]  Theoretical and Experimental Investigations of Circular Dichroism and Absolute Configuration Determination of Chiral Anthracene Photodimers, Wakai, H. Fukasawa,  C. Yang, T. Mori* and Y. Inoue*, J. Am. Chem. Soc., 2012134, 4990-4997. DOI : 10.1021/ja300522y
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[3]    Comprehensive Chiroptical Spectroscopy, 2 Volume Set , C. Yang and Y. Inoue, Compr, Chiroptical Spectrosc. , 2012, 2, 317-353. ISBN: 978-0-470-64135-4
[2]   CRC Handbook of Organic Photochemistry and Photobiology, Third Edition - Two Volume Set, C. Yang and Y. Inoue,  Org. Photochem. Photobiol. (3rd Ed.), 2012, 1, 125-176. ISBN: 9781439899335 - CAT# K14351
[1]   Supramolecular Photochirogenesis with Novel Cyclic Tetrasaccharide: Enantiodifferentiating Photoisomerization of (Z)-Cyclooctene with Cyclic Nigerosylnigerose-Based Sensitizers, C. Yang*, W. Liang, M. Nishijima, G. Fukuhara, T. Mori, H. Hiramatsu, Y. Dan-oh, K. Tsujimoto and Y. Inoue *Chirality, 201224, 921-927. DOI: 10.1002/chir.22014
 

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