picture
 
林丽丽
职称与职务
教 授
专      业
有机化学
电      话
E-Mail
简  历
1999–2003 ,四川大学,化学学院应用化学专业,本科
2003–2008 ,四川大学,化学学院有机化学专业,博士
2008–2011 ,四川大学,化学学院有机化学专业,讲师
2011–2016 ,四川大学,化学学院有机化学专业,副教授,硕导
2016 至今 四川大学,化学学院有机化学专业,教授
主要研究方向
不对称催化反应及其在天然产物合成中的应用。
主要工作业绩

        从事不对称合成领域的科研工作。近年来已经在Chem. Eur. J.Chem. Commun., Org. Lett.等刊物上发表多篇论文。目前承担国家自然科学基金面上项目两项:催化不对称Meerwein-Ponndorf-Verley类反应研究(批准号:21372162),经费85万元,执行时间:2014.01-2017.12;催化不对称反电子需求环化反应合成双杂原子环状化合物研究(批准号:21572136), 直接经费65万元,执行时间:2016.01-2019.12

      作为第三完成人获得2009年教育部自然科学奖一等奖和2012年国家自然科学奖二等奖。
代表性成果 (获奖成果、专著、论文、专利)
1.Lili Lin, Xiaoming Feng*, Catalytic Strategies for Diastereodivergent Synthesis, Chem. Eur. J. 2017, 23, 6464–6482.
2.Wangbin Wu, Sijia Zou, Lili Lin,* Jie Ji, Yuheng Zhang, Baiwei Ma, Xiaohua Liu, Xiaoming Feng*, Catalytic asymmetric Meerwein–Ponndorf–Verley reduction of glyoxylates induced by a chiral N,N’-dioxide/Y(OTf)3 complex, Chem. Commun., 2017, 53, 3232-3235.
3.Kai Fu, Jingchuan Zhang, Lili Lin,* Jun Li, Xiaohua Liu, and Xiaoming Feng*, Chiral N,N’-Dioxide/Lanthanide(III) Complex Catalyzed Asymmetric Bisvinylogous Mukaiyama Aldol Reactions, Org. Lett. 2017, 19, 332?335.
4.Juhua Feng, Xiao Yuan, Weiwei Luo, Lili Lin,* Xiaohua Liu, Xiaoming Feng*, Chiral N,N’-Dioxide-Organocatalyzed Regio-, Diastereo- and Enantioselective Michael Addition–Alkylation Reaction, Chem. Eur. J. 2016, 22, 15650–15653.
5.Jianfeng Zheng, Lili Lin,* Li Dai, Xiao Yuan, Xiaohua Liu, Xiaoming Feng*, Chiral N,N′-Dioxide–Scandium(III) Complex-Catalyzed Asymmetric Friedel-Crafts Alkylation Reaction of ortho-Hydroxybenzyl Alcohols with C3-Substitued N-Protected Indoles, Chem. Eur. J. 2016, 22, 18254-18258
6.Xiaohu Zhao, Hongjiang Mei, Qian Xiong, Kai Fu, Lili Lin,* Xiaohua Liu, Xiaoming Feng*, Highly enantioselective construction of carbazole derivatives via [4+2] cycloaddition of silyloxyvinylindoles and ?,γ-unsaturated a-ketoesters, Chem. Commun., 2016, 52,10692–10695
7.Yan Lu, Yuhang Zhou, Lili Lin,* Haifeng Zheng, Kai Fu, Xiaohua Liu, Xiaoming Feng*, N,N’-Dioxide/nickel(II)-catalyzed asymmetric Diels–Alder reaction of cyclopentadiene with 2,3-dioxopyrrolidines and 2-alkenoyl pyridines, Chem. Commun., 2016, 52, 8255—8258.
8.Kai Fu, Jianfeng Zheng, Lili Lin,* Xiaohua Liu and Xiaoming Feng*, Chiral N,N’-dioxide–In(OTf)3-catalyzed asymmetric vinylogous Mukaiyama aldol reactions, Chem. Commun., 2015, 51, 3106—3108.
9.Xiying Zhang, Jianlin Zhang, Lili Lin,* Haifeng Zheng, Wangbin Wu, Xiaohua Liu, Xiaoming Feng*, Chiral N,N’-Dioxide-Zinc(II) Complex-Catalyzed Asymmetric Aza-Friedel–Crafts Reaction of Isatin-Derived Ketimines with Indoles, Adv. Synth. Catal. 2016, 358, 3021-3026.
10.Xiao Xiao, Lili Lin,* Xiangjin Lian, Xiaohua Liu, Xiaoming Feng*, Catalytic asymmetric α-amination of β-ketoesters and β-keto amides with a chiral N,N’-dioxide–copper(I) complex, Org. Chem. Front., 2016, 3, 809–812
11.Xiao Yuan, Lili Lin,* Weiliang Chen, Wangbin Wu, Xiaohua Liu, Xiaoming Feng*, Synthesis of Chiral Tetrahydrofurans via Catalytic Asymmetric [3 + 2] Cycloaddition of Heterosubstituted Alkenes with Oxiranes, J. Org. Chem. 2016, 81, 1237?1243.
12.Ruixue Peng, Lili Lin,* Yuheng Zhang, Wangbin Wu, Yan Lu, Xiaohua Liu, Xiaoming Feng*, The assignment of the configuration for α-hydroxy acid esters using a CEC strategy, Org. Biomol. Chem., 2016, 14, 5258–5262.
13.Xuan Fu, Lili Lin,* Yong Xia, Pengfei Zhou, Xiaohua Liu, Xiaoming Feng*, Catalytic asymmetric [3 + 3] annulation of cyclopropanes with mercaptoacet aldehyde, Org. Biomol. Chem., 2016, 14, 5914–5917.
14.Jianfeng Zheng, Lili Lin*, Kai Fu, Haifeng Zheng, Xiaohua Liu, Xiaoming Feng*, Synthesis of Optically Pure Spiro[cyclohexane-oxindoline] Derivatives via Catalytic Asymmetric Diels?Alder Reaction of Brassard-Type Diene with Methyleneindolines, J. Org. Chem. 2015, 80, 8836?8842
15.Ruixue Peng, Lili Lin*, Weidi Cao, Jing Guo, Xiaohua Liu, Xiaoming Feng*, A racemic N,N’-dioxide-iron(III) complex chemosensor for determination of enantiomeric excess, concentration and identity of hydroxy carboxylic acids with circular dichroism and ?uorescence responses, Tetrahedron Letters 2015, 56, 3882–3885.
16.Hongjiang Mei, Xiao Xiao, Xiaohu Zhao, Bing Fang, Xiaohua Liu, Lili Lin,* Xiaoming Feng*, Catalytic Asymmetric Henry Reaction of Nitroalkanes and Aldehydes Catalyzed by a Chiral N,N’-Dioxide/Cu(I) Complex, J. Org. Chem. 2015, 80, 2272?2280.
17.Lili Lin, Yulong Kuang, Xiaohua Liu, Xiaoming Feng*, Indium(III)-Catalyzed Asymmetric Hetero-Diels–Alder Reaction of Brassard-Type Diene with Aliphatic Aldehydes, Org. Lett, 2011, 13, 3868-3871.
18.Lili Lin, Zhenling Chen, Xu Yang, Xiaohua Liu, and Xiaoming Feng*, An Efficient Enantioselective Hetero-Diels-Alder Reaction of Brassard’s Dienes with Aliphatic Aldehydes: A One-Step Synthesis of (R)-(+)-Kavain and (S)-(+)-Dihydrokavain, Org. Lett. 2008, 10, 1311-1314.
19.Lili Lin, Qian Fan, Bo Qin, and Xiaoming Feng*, Highly Enantio- and Diasteroselective Brassard Type Hetero-Diels-Alder Approach to 5-Methyl-Containing α,β-Unsaturated δ-Lactones, J. Org. Chem. 2006, 71, 4141-4146.
20.Lili Lin, Xiaohua Liu, Xiaoming Feng, Asymmetric Hetero-Diels–Alder Reactions of Danishefsky’s and Brassard’s Dienes with Aldehydes, Synlett 2007, 14, 2147-2157.
21.Zhenhua Dong, Juhua Feng, Weidi Cao, Xiaohua Liu, Lili Lin*, Xiaoming Feng*, N,N’-Dioxide–nickel(II) complex catalyzed asymmetric Michael addition of cyclic 1,3-dicarbonyl compounds to ?β,γ-unsaturated α-ketoesters, Tetrahedron Lett, 2011, 52, 3433-3436.
 

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