Xiaoqi Yu

EDUCATION AND WORKING EXPERIENCE:

Sept. 1983 - Mar. 1993:   Organic Chemistry and Bio-organic Chemistry BSc, MS, PhD, Department of Chemistry, Sichuan University.

April 1993 - June 1999:    Lecturer, Associate Professor, Department of Chemistry, Sichuan University.

April 1998 - Mar. 2001:    Research Associate, Department of Chemistry, the University of Hong Kong.

July 1999 - Oct. 2009:      Professor, College of Chemistry, Sichuan University.

Nov. 2009 - present:         Chang Jiang Chair Professor, College of Chemistry, Sichuan University.

Dec. 2010 - present:        Dean and Chang Jiang Chair Professor, College of Chemistry, Sichuan University.

SELECTED AWARDS AND HONORS:

2001: Excellent teacher award          by College of Chem, Sichuan University

2003: Outstanding young scientist award        by Sichuan Province

2003: New century excellent talent award      by Ministry of Education of China

2004: Excellent teacher award                         by Sichuan University

2006: Scholar Leadership awarded                  by Sichuan Province

2007: Distinguished Young Scholars Awarded  by National Science Foundation of China

2009: Chang Jiang Chair Professor                   by Ministry of Education of China

RESEARCH INTERESTS AND EXPERTISE:

1. Biomedical Materials Chemistry

2. Methodology of Organic Syntheses

REPRESENTATIVE PUBLICATIONS:

(5).     Zhang, Q.-F., Yi, W.-J., Wang, B., Zhang, J.*, Ren, L.-F., Chen, Q.-M., Guo, L.-D.*, Yu, X.-Q.*, Linear polycations by ring-opening polymerization as non-viral gene delivery vectors. Biomaterials, 2013, 34, 5391-5401.

(4).     Huang, Q.-D., Ren, J., Chen, H., Ou, W.-J., Zhang, J.*, Fu, Y., Zhu, W.*, Yu, X.-Q.*, Cyclen-Based Cationic Lipids Containing Carbamate Linkages as Efficient Gene Delivery Vectors with Low Toxicity. ChemPlusChem, 2012, 77, 584-591.

(3).     Huang, Q.-D., Zhong, G.-X., Zhang, Y., Ren, J., Fu, Y., Zhang, J.*, Zhu, W.*, Yu, X.-Q.*, Cyclen-Based Cationic Lipids for Highly Efficient Gene Delivery towards Tumor Cells. PLoS ONE, 2011, 6, e23134. doi:10.1371/journal.pone.0023134.

(2).     Chen, X., Huang, Z., Chen, S.-Y., Li, K., Yu, X.-Q.*, Pu, L.*, Enantioselective Gel Collapsing: A New Means of Visual Chiral Sensing. J. Am. Chem. Soc., 2010, 132, 7297–7299.

(1).     Wen, J., Zhang, J., Chen, S.-Y., Li, J., Yu, X.-Q.*, Iron-Mediated Direct Arylation of Unactivated Arenes. Angew. Chem. Int. Ed., 2008, 47, 8897-8900.

SELECTED PUBLICATIONS

(110). Zhang, Q.-F., Yi, W.-J., Wang, B., Zhang, J.*, Ren, L.-F., Chen, Q.-M., Guo, L.-D.*, Yu, X.-Q.*, Linear polycations by ring-opening polymerization as non-viral gene delivery vectors, Biomaterials, 2013, 34, 5391-5401.

(109). Chen, W., Tay, J.-H. Ying, J., Sabat, M., Yu, X.-Q.*, Pu, L.*, A quick access to the spirotricyclic core analogue of mangicol A by a Rh( I )-catalyzed tandem Pauson–Khand/[4+2] cycloaddition, Chem. Commun., 2013, 49, 170-172.

(108). Xu, H.-R., Li, K.*, Liu, Q., Wu, T.-M., Wang, M.-Q., Hou, J.-T., Huang, Z., Xie, Y.-M.*, Yu, X.-Q.*, Dianthracene–cyclen conjugate: the ?rst equal-equivalent responding ?uorescent chemosensor for Pb2+ in aqueous solution, Analyst, 2013, 138, 2329–2334.

(107). Wu, M.-Y., He, T., Li, K.*, Wu, M.-B., Huang, Z., Yu, X.-Q.*, A real-time colorimetric and ratiometric ?uorescent probe for sul?te, Analyst, 2013, 138, 3018–3025.

(106). Liu, Q., Jiang, Q.-Q., Yi, W.-J., Zhang, J.*, Zhang, X.-C., Wu, M.-B., Zhang, Y.-M., Zhu, W.*, Yu, X.-Q.*, Novel imidazole-functionalized cyclen cationic lipids: Synthesis and application as non-viral gene vectors, Bioorg. Med. Chem. 2013, 21, 3105–3113.

(105). Li, K., Xu, H.-R., Yu, K.-K., Hou, J.-T., Yu, X.-Q.*, A coumarin-based chromogenic and ratiometric probe for hydrazine, Anal. Methods, 2013, 5, 2653-2656.

(104). Chen, W., Tay, J.-H. Ying, J., Yu,,X.-Q.*, Pu, L.*, Catalytic Asymmetric Enyne Addition to Aldehdyes and Rh(I)-Catalyzed Stereoselective Domino Pauson ? Khand/[4 + 2] Cycloaddition, J. Org. Chem. 2013, 78, 2256 – 2265.

(103). Zhou, Y.-J., Hu, C.-L., Wang, N.*, Zhang, W.-W., Yu, X.-Q.*, Puri?cation of porcine pancreatic lipase by aqueous two-phase systems of polyethylene glycol and potassium phosphate, J. Chromatography B, 2013, 926, 77–82.

(102). Lu, Q.-S., Hou, J.-T., Wang, J., Xu, B.-Y., Zhang, J.*, Yu, X.-Q.*, Multichannel Chromogenic and Chiral Anions Recognition by Imidazolium Functionalized BINOL Derivatives, Chin. J. Chem. 2013, 31, 641-650.

(103). Zhou, L.-H., Wang, N.*, Zhang, W., Xie, Z.-B., Yu, X.-Q.*, Catalytical promiscuity of a-amylase: Synthesis of 3-substituted 2H-chromene derivatives via biocatalytic domino oxa-Michael/aldol condensations, J. Mol. Catal. B: Enzym., 2013, 91, 37–43.

(101). Tao, F-Y., Wang, C.-G., Ma, K.-Y., Li, D.-L., Tan, L.-L., Zhang, J., Dai, Y.*, Yu, X.-Q.*, A facile synthesis and application of protoporphyrin derivatives on reducing the tobacco specific N-nitroamines levels of smoke, J. Porphyrins Phthalocyanines 2013, 17, 309–316.

(100). Xun, M.-M., Zhang, X.-C., Zhang, J.*, Jiang, Q.-Q., Yi, W.-J., Zhu, W.*, Yu, X.-Q.*, Low molecular weight PEI-based biodegradable lipopolymers as gene delivery vectors, Org. Biomol. Chem., 2013, 11, 1242–1250.

(99).   Hou, J.-T., Li. K.*, Yu, K.-K., Wu, M.-Y., Yu, X.-Q.*, Coumarin–DPA–Cu(II) as a chemosensing ensemble towards histidine determination in urine and serum, Org. Biomol. Chem., 2013, 11, 717-720.

(98).   Hou, J.-T., Li, K.*, Liu, B.-Y., Liao, Y.-X., Yu, X.-Q.*, The ?rst ratiometric probe for lysine in water, Tetrahedron, 2013, 69, 2118-2123.

(97).   He, T., Li, K.*, Wu, M.-Y., Wu, M.-B., Wang, N., Pu, L., Yu, X.-Q.*, Water promoted enantioselective aldol Reaction by proline-cholesterol and -diosgenin based amphiphilic organocatalysts, Tetrahedron, 2013, 69, 5136-5143.

(96).   Xie, Z.-B., Wang, N.*, Jiang, G.-F., Yu, X.-Q.*, Biocatalytic asymmetric aldol reaction in buffer solution, Tetrahedron Lett. 2013, 54, 945–948.

(95).   Feng, J., Yang, X.-B., Liang, S., Zhang, J.*, Yu, X.-Q.*, An ef?cient oxidative coupling method for synthesis of novel diastereomeric biaryl diols derived from estrone, Tetrahedron Lett. 2013, 54, 355–357.

(94).   Wang, J., Wang, S., Wang, G., Zhang, J.*, Yu, X.-Q.*, Iron-mediated direct arylation with arylboronic acids through an aryl radical transfer pathway, Chem. Commun., 2012, 48, 11769–11771.

(93).   Huang, Z., Du, J., Zhang, J., Yu, X.-Q.*, Pu, L.*, A simple and e?cient ?uorescent sensor for histidine, Chem. Commun., 2012, 48, 3412-3414.

(92).   Huang, Q.-D., Ren, J., Chen, H., Ou, W.-J., Zhang, J.*, Fu, Y., Zhu, W.*, Yu, X.-Q.*, Cyclen-Based Cationic Lipids Containing Carbamate Linkages as Efficient Gene Delivery Vectors with Low Toxicity, ChemPlusChem, 2012, 77, 584-591.

(91).   Wen, J., Zhang, R.-Y., Chen, S.-Y., Zhang J.*, Yu, X.-Q.*, Direct Arylation of Arene and N-Heteroarenes with Diaryliodonium Salts without the Use of Transition Metal Catalyst, J. Org. Chem., 2012, 77, 766-771.

(90).   Wang, M.-Q., Li, K.*, Hou, J.-T., Wu, M.-Y., Huang, Z., Yu, X.-Q.*, BINOL-Based Fluorescent Sensor for Recognition of Cu(II) and Sul?de Anion in Water, J. Org. Chem., 2012, 77, 8350?8354.

(89).   Chen, W., Tay, J.-H., Yu, X.-Q.*, Pu, L.*, Diastereoselective [4 + 1] Cycloaddition of Alkenyl Propargyl Acetates with CO Catalyzed by [RhCl(CO)2]2, J. Org. Chem., 2012, 77, 6215?6222.

(87).   Wu, M.-Y., Li, K*, Hou, J.-T., Huang, Z., Yu, X.-Q.*, A selective colorimetric and ratiometric ?uorescent probe for hydrogen sul?de, Org. Biomol. Chem., 2012, 10, 8342-8347.

(86).   Huang, Q.-D., Ren, J., Ou, W.-J., Fu, Y., Cai, M.-Q., Zhang, J.*, Zhu, W.*, Yu, X.-Q.*, Cationic Lipids Containing Cyclen and Ammonium Moieties as Gene Delivery Vectors, Chem. Biol. Drug Des., 2012, 79, 879-887.

(85).   Li, S., Wang, Y., Wang, S., Zhang, J.*, Wu, S.-F., Wang, B.-L., Zhu, W.*, Yu, X.-Q.*, Biodegradable cyclen-based linear and cross-linked polymers as non-viral gene vectors, Bioorg. Med. Chem., 2012, 20, 1380–1387.

(84).   Zhang, W.-W., Wang, N.*, Zhou, Y.-J., He, T., Yu, X.-Q.*, Enhancement of activity and stability of lipase by microemulsion-based organogels (MBGs) Immobilization and application for synthesis of arylethyl acetate, J. Mol. Catal. B: Enzymatic, 2012, 78, 65–71.

(83).   Feng, J., Liang, S., Chen, S.-Y., Zhang, J.*, Fu, S.-S., Yu, X.-Q.*, A Metal-Free Oxidative Esterification of the Benzyl C-H Bond, Adv. Synth. Catal., 2012, 354, 1287-1292.

(82).   Huang, Z., Du, J., Zhang, J., Yu, X.-Q.*, Pu, L.*, Highly selective ?uorescent recognition of Zn2+ in water by terpyridine–CuCl2, Anal. Methods, 2012, 4 , 1909-1912.

(81).   Xie, Z.-B., Wang, N.*, Wu, M.-Y., He, T., Le, Z.-G., Yu, X.-Q.*, Catalyst-free and solvent-free Michael addition of 1,3-dicarbonyl compounds to nitroalkenes by a grinding method, Beilstein J. Org. Chem., 2012, 8, 534–538.

(80).   Wen, J., Fu, Y., Zhang, R.-Y., Zhang, J.*, Chen, S.-Y., Yu, X.-Q.*, A simple and ef?cient synthesis of pyrazoles in water, Tetrahedron, 2011, 67, 9618-9621.

(79).   Zhang, Q.-F., Yang, W.-H., Yi, W.-J., Zhang, J.*, Ren, J., Luo, T.-Y., Zhu, W.*, Yu, X.-Q.*, TACN-containing cationic lipids with ester bond: Preparation and application in gene delivery Bioorg. Med. Chem. Lett., 2011, 21, 7045–7049.

(78).   Wang, J., Hou, J.-T., Wen, J., Zhang, J.*, Yu, X.-Q.*, Iron-catalyzed direct amination of azoles using formamides or amines as nitrogen sources in air, Chem. Commun., 2011, 47, 3652-3654.

(77).   Wang, M.-Q., Liu, J.-L., Wang, J.-Y., Zhang, D.-W., Zhang, J., Streckenbach, F., Tang, Z.*, Lin, H.-H.*, Liu, Y., Zhao, Y.-F., Yu, X.-Q.*, Site-selective DNA Hydrolysis Induced by a Metal-free Peptide Nucleic Acid-Cyclen Conjugate, Chem. Commun.,  2011, 47, 11059-11061.

(76).   Liu, J.-L., Ma, Q.-P., Huang, Q.-D., Yang, W.-H., Zhang, J.*, Wang, J.-Y., Zhu, W., Yu, X.-Q.*, Cationic lipids containing protonated cyclen and different hydrophobic groups linked by uracil-PNA monomer: Synthesis and application for gene delivery, Eur. J. Med. Chem., 2011, 46, 4133-4141.

(75).   Huang, Q.-D., Zhong, G.-X., Zhang, Y., Ren, J., Fu, Y., Zhang, J.*, Zhu, W.*, Yu, X.-Q.*, Cyclen-Based Cationic Lipids for Highly Efficient Gene Delivery towards Tumor Cells, PLoS ONE, 2011, 6, e23134. doi:10.1371/journal.pone.0023134.

(74).   Huang, Q.-D., Ou, W.-J., Chen, H., Feng, Z.-H., Wang, J.-Y., Zhang, J.*, Zhu, W.*, Yu, X.-Q.*, Novel cationic lipids possessing protonated cyclen and imidazolium salt for gene delivery, Eur. J. Pharm. Biopharm., 2011, 78, 326–335.

(73).   Wang, H.-Y., Zhou, Y.-J., Wang, Z., Wang, N.*, Li, K., Yu, X.-Q.*, Enzyme-Catalyzed Synthesis of a Novel Thermosensitive Polyester with Pendant Ketoprofen, Macromol. Biosci., 2011, 11, 595–599.

(72).   Wu, M.-Y., Li, K.*, Wang, N., He, T., Yu, X.-Q.*, A Novel Catalyst-Free Tandem Reaction for the Synthesis of 5-Hydroxy-1,5-dihydro-2H-pyrrol-2-ones in Water Medium, Synthesis, 2011, 12, 1831–1839.

(71).   Li, S., Wang, Y., Zhang, J.*, Yang, W.-H., Dai, Z.-H., Zhu, W.*, Yu, X.-Q.*, Biodegradable cross-linked poly(amino alcohol esters) based on LMW PEI for gene delivery, Mol. BioSyst., 2011, 7, 1254-1262.

(70).   Yi, W.-J., Feng, Z.-H., Zhang, Q.-F., Zhang, J.*, Li, L.-D., Zhu, W.*, Yu, X.-Q.*, Diol glycidyl ether-bridged cyclens: preparation and their applications in gene delivery, Org. Biomol. Chem., 2011, 9, 2413-2421.

(69).   Wang, M.-Q., Zhang, J., Zhang, Y., Zhang, D.-W., Liu, Q., Liu, J.-L., Lin, H.-H.*, Yu, X.-Q.*, Metal-free Cleavage Efficiency toward DNA by a Novel PNA Analog-bridged Macrocyclic Polyamine, Bioorg. Med. Chem. Lett., 2011, 21, 5866-5869.

(68).   Ye, Y.-H., Zhang, J., Wang, G., Chen, S.-Y.*, Yu, X.-Q.*, Cobalt-catalyzed benzylic CeH amination via dehydrogenative-coupling reaction, Tetrahedron, 2011, 67, 4649-4654.

(67).   Hou, J.-T., Zhang, Q.-F., Xu, B.-Y., Lu, Q.-S., Liu, Q., Zhang, J., Yu, X.-Q.*, A novel BINOL-based cyclophane via click chemistry: synthesis and its applications for sensing silver ions, Tetrahedron Lett., 2011, 52, 4927–4930.

(66).   Du, X., Wang, Q.*, He, X., Peng, R.-G., Zhang, X., Yu, X.-Q.*, Highly enantioselective addition of linear alkyl alkynes to aromatic aldehydes, Tetrahedron: Asymmetry, 2011, 22, 1142–1146.

(65).   Wu, M.-Y., Li, K.*, He, T., Feng, X.-W., Wang, N., Wang, X.-Y., Yu, X.-Q.*, A novel enzymatic tandem process: utilization of biocatalytic promiscuity for high stereoselective synthesis of 5-hydroxyimino-4,5-dihydrofurans, Tetrahedron, 2011, 67, 2681-2688.

(64).   Wu, M.-Y., Wang, M.-Q., Li, K.*, Feng, X.-W., He, T., Wang, N., Yu, X.-Q.*, An ef?cient, transition-metal-free process for the synthesis of substituted dihydrofurans via a Michael/cyclization tandem reaction, Tetrahedron Lett. 2011, 52, 679–683.

(63).   Huang, Z., Chen, X., Zhang, J., Yu, X.-Q.*, Pu, L.*, Connecting BINOL and Terpyridine:  The Electronic Effects of the Linkage, Tetrahedron Lett., 2011, 52, 5497–5500.

(62).   Zhang, Y., Wang, M.-Q., Zhang, J., Zhang, D.-W., Lin, H.-H.*, Yu, X.-Q.*, Synthesis, DNA Binding, and Cleavage Studies of Novel PNA Binding Cyclen Complexes, Chem. Biodivers., 2011, 8, 827-840.

(61).   Zhang, Y., Huang, Y., Zhang, J., Zhang, D.-W., Liu, J.-L., Liu, Q., Lin, H.-H.*, Yu, X.-Q.*, Synthesis, DNA binding and cleavage studies of the copper(II) complexes of PNA-cyclen conjugates,  Sci. China Chem., 2011, 54(1), 129-136.

(60).   Wang, H.-Y., Zhang, W.-W., Wang, N.,* Li, C., Li, K., Yu, X.-Q.*, Biocatalytic Synthesis and in Vitro Release of Biodegradable Linear Polyesters with Pendant Ketoprofen Biomacromolecules, 2010, 11, 3290–3293.

(59).   Liu, Q., Zhang, J., Wang, M.-Q., Zhang, D.-W., Lu, Q.-S., Huang, Y., Lin, H.-H.*, Yu, X.-Q.*, Synthesis, DNA binding and cleavage activity of macrocyclic polyamines bearing mono- or bis-acridine moieties, Eur. J. Med. Chem., 2010, 45, 5302-5308.

(58).   Li, C., Zhou, Y.-J., Wang N.*, Feng, X.-W., Li, K., Yu, X.-Q.*, Promiscuous protease-catalyzed aldol reactions: A facile biocatalytic protocol for carbon–carbon bond formation in aqueous media, J. Biotech., 2010, 150, 539–545.

(57).   Qin, J., Meng, X.-W., Li, B.-J., Ha, W., Yu, X.-Q.*, Zhang, S.*, Self-assembly of b-cyclodextrin and pluronic into hollow nanospheres in aqueous solution, J. Colloid Interface Sci., 2010, 350, 447–452.

(56).   He, T., Li, K.*, Wu, M.-Y., Feng, X.-W., Wang, N., Wang, H.-Y., Li, C., Yu, X.-Q.*,  Utilization of biocatalytic promiscuity for direct Mannich reaction, J. Mol. Catal. B: Enzym., 2010, 67, 189–194.

(55).   Wang, L., Li, C., Wang, N.*, Li, K., Chen, X., Yu, X.-Q.*, Enzyme-mediated domino synthesis of 2-alkylbenzimidazoles in solvent-free system: A green route to heterocyclic compound, J. Mol. Catal. B: Enzym., 2010, 67, 16–20.

(54).   Turlington, M., Yue, Y., Yu, X.-Q.*, Pu, L.*, Catalytic Asymmetric Synthesis of Chiral Propargylic Alcohols for the Intramolecular Pauson-Khand Cycloaddition, J. Org. Chem., 2010, 75, 6941–6952.

(53).   Feng, X.-W., Wang, J., Zhang, J., Yang, J., Wang, N., Yu, X.-Q.*, Copper-Catalyzed Nitrogen Loss of Sulfonylhydrazones: A Reductive Strategy for the Synthesis of Sulfones from Carbonyl Compounds, Org. Lett., 2010, 12, 4408-4411.

(52).   Lu, Q.-S., Zhang, J., Jiang, L., Hou, J.-T., Yu, X.-Q.*, Highly selective ratiometric estimation of ?uoride ion based on a BINOL imidazolium cyclophane with dual-channel, Tetrahedron Lett., 2010, 51, 4395–4399.

(51).   Chen, X., Huang, Z., Chen, S.-Y., Li, K., Yu, X.-Q.*, Pu, L.*, Enantioselective Gel Collapsing: A New Means of Visual Chiral Sensing, J. Am. Chem. Soc., 2010, 132, 7297–7299.

(50).   Wen, J., Qin, S., Ma, L.-F., Dong, L., Zhang, J., Liu, S.-S., Duan, Y.-S., Chen, S.-Y., Hu, C.-W.*, Yu, X.-Q.*, Iron-Mediated Direct Suzuki-Miyaura Reaction: A New Method for the ortho-Arylation of Pyrrole and Pyridine, Org. Lett., 2010, 12, 2694-2697.

(49).   Xiang, Y.-Z., Feng, Z.-H., Zhang, J.*, Liao, Y.-L., Yu, C.-J., Yi, W.-J., Zhu, W.*, Yu, X.-Q.*, Linear cyclen-based polyamine as a novel and efficient reagent in gene delivery, Org. Biomol. Chem., 2010, 8, 640–647.

(48).   Chen, X., Chen, W., Wang, L., Yu, X.-Q.*, Huang, D.-S., Pu, L.*, Synthesis of a C1 symmetric BINOL–terpyridine ligand and highly enantioselective methyl propiolate addition to aromatic aldehydes, Tetrahedron, 2010, 66, 1990–1993.

(47).   Chen, X., Liu, Q., Sun, H.-B., Yu, X.-Q.*, Pu, L.*, A BINOL–terpyridine-based multi-task catalyst for a sequential oxidation and asymmetric alkylation of alcohols, Tetrahedron Lett., 2010, 51, 2345–2347.

(46).   Huang, Y., Liu, J.-L., Zhang, J., Liu, Q., Hou, J.-T., Zhang, Y., Zhang, D.-W., Lu, Q.-S., Chen, S.-Y., Lin, H.-H., Yu, X.-Q.*, Interaction of bis-aryl functionalized molecules with nucleosides and nucleic acids, Sci. China Chem., 2010, 53, 103–112.

(45).   Zhou, L.-H., Yu, X.-Q.*, Pu, L.*, Reactivity of a propiolate dimer with nucleophiles and an efficient synthesis of dimethyl a-aminoadipate, Tetrahedron Lett., 2010, 51, 425–427.

(44).   Zhou, L.-H., Yu, X.-Q.*, Pu, L.*, Na-promoted aerobic oxidation of alcohols to ketones, Tetrahedron Lett., 2010, 51, 475–477.

(43).   Meng, X.-W., Qin, J., Liu, Y., Fan, M.-M., Li, B.-J.*Zhang, S.*, Yu, X.-Q., Degradable hollow spheres based on self-assembly inclusion, Chem. Commun., 2010, 46, 643–645.

(42).   Zhang, J., Meng, X.-G., Zeng, X.-C., Yu, X.-Q.*, Metallomicellar supramolecular systems and their applications in catalytic reactions, Coord. Chem. Rev., 2009, 253, 2166–2177.

(41).   Yue, Y., Yu, X.-Q.*, Pu, L.*, Base-Catalyzed Highly Stereoselective Conversion of g-Hydroxy- a,b-acetylenic Esters to g-Acetoxy Dienoates, Chem. Eur. J., 2009, 15, 5104-5107.

(40).   Lu, Q.-S., Dong, L., Zhang, J., Li, J., Jiang, L., Huang, Y., Qin, S., Hu, C.-W., Yu, X.-Q.*, Imidazolium-Functionalized BINOL as a Multifunctional Receptor for Chromogenic and Chiral Anion Recognition, Org. Lett., 2009, 11, 669-672.

(39).   Li, K., He, T., Li, C., Feng, X.-W., Wang, N., Yu, X.-Q.*, Lipase-catalysed direct Mannich reaction in water: utilization of biocatalytic promiscuity to C-C bond formation in a “one-pot” synthesis, Green Chem., 2009, 11, 777-779.

(38).   Zhou, L.-H., Yu, X.-Q.*, Pu, L.*, Reactivity of γ-Hydroxy-α,β-acetylenic Esters with Amines: Facile Synthesis of the Optically Active 4-Amino-2(5H)-furanones, J. Org. Chem., 2009, 74, 2013–2017.

(37).   Huang, Y., Zhang, Y., Zhang, J., Zhang, D.-W., Lu, Q.-S., Liu, J.-L., Chen, S.-Y., Lin, H.-H., Yu, X.-Q.*, Synthesis, DNA binding and photocleavage study of novel anthracene-appended macrocyclic polyamines, Org. Biomol. Chem., 2009, 7, 2278-2285.

(36).   Wang, H.-Y., Li, C., Wang, N.*, Li, K., Feng, X.-W., He, T., Yu, X.-Q.*, Two-step enzymatic selective synthesis of water-soluble ketoprofen -saccharide conjugates in organic media, Bioorg. Med. Chem., 2009, 17, 1905-1910.

(35).   Li, K., Zhou, L.-H., Zhang, J., Chen, S.-Y., Zhang, Z.-W., Zhang, J.-J., Lin, H.-H., Yu, X.-Q.*, “Self-activating” Chemical Nuclease: Ferrocenyl Cyclen Cu(II) Complexes Act as Efficient DNA Cleavage Reagents in the Absence of Reductant, Eur. J. Med. Chem., 2009, 44, 1768-1772.

(34).   Xiang, Y.-Z., Liao, Y.-L., Zhang, J.*, Zhang, D.-W., Chen, S.-Y., Lu, Q.-S., Zhang, Y., Lin, H.-H,*, Yu, X.-Q.*, Linear disulfide-containing low polymer as efficient DNA cleavage reagent, Bioorg. Med. Chem. Lett., 2009, 19, 3458–3460.

(33).   Li, J., Zhang, J., Lu, Q.-S., Yue, Y., Huang, Y., Zhang, D.-W., Lin, H.-H., Chen, S.-Y., Yu, X.-Q.*, Hydrolytic cleavage of DNA by urea-bridged macrocyclic polyamines, Eur. J. Med. Chem., 2009, 44, 5090–5093.

(32).   Chen, S.-Y., Zhang, J., Li, Y.-H., Wen, J., Bian, S.-Q., Yu, X.-Q.*, Cobalt-catalyzed homo-coupling of aryl and alkenyl bromide using atmospheric oxygen as oxidant, Tetrahedron Lett., 2009, 50, 6795–6797.

(31).   Feng, X.-W., Li, C., Wang, N.*, Li, K., Zhang, W.-W., Wang, Z., Yu, X.-Q.*Lipase-catalysed decarboxylative aldol reaction and decarboxylative Knoevenagel reaction, Green Chem., 2009, 11, 1933-1936.

(30).   Yue, Y, Turlington, M., Yu, X.-Q.*, Pu, L.*, 3,3’-Anisyl-Substituted BINOL, H4BINOL, and H8BINOL Ligands: Asymmetric Synthesis of Diverse Propargylic Alcohols and Their Ring-Closing Metathesis to Chiral Cycloalkenes, J. Org. Chem., 2009, 74, 8681-8689.

(29).   Wen, J., Zhang, J., Chen, S.-Y., Li, J., Yu, X.-Q.*, Iron-Mediated Direct Arylation of Unactivated Arenes, Angew. Chem. Int. Ed., 2008, 47, 8897-8900.

(28).   Zheng, Z.-G., Wen, J., Wang, N., Wu, B., Yu, X.-Q.*, N-Arylation of amines, amides, imides and sulfonamides with arylboroxines catalyzed by simple copper salt/EtOH system, Beilstein J. Org. Chem., 2008, 4, No. 40. doi:10.3762/bjoc.4.40

(27).   Li, C., Feng, X.-W., Wang, N., Zhou, Y.-J., Yu, X.-Q.*, Biocatalytic promiscuity: the first lipase-catalysed asymmetric aldol reaction, Green Chem., 2008, 10, 616-618.

(26).   Yang, X.-B., Feng, J., Zhang, J., Wang, N., Wang, L., Liu, J.-L., Yu, X.-Q*, Highly Enantioselective Hetero-Diels?-Alder Reaction of trans-1-Methoxy-2-methyl-3-trimethylsiloxybuta-1,3-diene with Aromatic and Aliphatic Aldehydes Catalyzed by 3-Substituted BINOL-Titanium Complex, Org. Lett., 2008, 10, 1299-1302.

(25).  Huang, Y., Lu, Q.-S., Zhang, J., Zhang, Z.-W., Zhang, Y., Chen, S.-Y., Li, K., Tan, X.-Y., Lin, H.-H., Yu, X.-Q.*, DNA cleavage by novel copper (II) complex and the role of ?-cyclodextrin in promoting cleavage, Bioorg. Med. Chem., 2008, 16, 1103-1110.

(24).   Yang, X.-B., Feng, J., Zhang, J., Zhang, Z.-W., Lin, H.-H., Zhou, L.-H., Yu, X.-Q.*, Synthesis, DNA binding and cleavage activities of the copper (II) complexes of estrogen-macrocyclic polyamine conjugates, Bioorg. Med. Chem., 2008, 16, 3871-3877.

(23).   Li, C., Wang, H.-Y. Wang, N.,* Fang, Y.-G., Chen, X., Yu, X.-Q.*, Highly regioselective enzymatic synthesis of polymerizable derivatives of methyl shikimate, Bioorg. Med. Chem. Lett., 2007, 17, 6687-6690.

(22).   He, L., Yu, J., Zhang, J., Yu, X.-Q.*, ?-Amidation of cyclic ethers catalyzed by simple copper salts and a mild and efficient preparation method for ?,?-aminoalcohols, Org. Lett., 2007, 9, 2277-2280.

(21).   Wang, Q., Chen, X., Tao, L., Wang, L., Xiao, D., Yu, X.-Q.*, Pu, L.*, Enantioselective Fluorescent Recognition of Amino Alcohols by a Chiral Tetrahydroxyl 1,1’-Binaphthyl Compound, J. Org. Chem., 2007, 72, 97-101.

(20).   Fang, Y.-G., Zhang, J., Chen, S.-Y., Jiang, N., Lin, H.-H., Zhang, Y., Yu, X.-Q.*, Chiral multinuclear macrocyclic polyamine complexes: Synthesis, characterization and their interaction with plasmid DNA, Bioorg. Med. Chem., 2007, 15, 696-701.

(19).   Wang, Q., Chen, S.-Y., Yu, X.-Q.*, Pu, L.*, 1,1’-Binaphthyl ligands with bulky 3,3’-tertiaryalkyl substitutes for the asymmetric alkyne addition to aromatic aldehydes, Tetrahedron, 2007, 63, 4422-4428.

(18). Zhao, Y.-C., Zhang, J., Huang, Y., Wang, G.-Q., Yu, X,-Q.*, DNA cleavage promoted by 2, 9-dimethyl-4, 7-diazadecane-2, 9-dithiol (DMDD) derivatives, Bioorg. Med. Chem. Lett., 2007, 17, 2745-2748.

(17).   Gao, G., Wang, Q., Yu, X.-Q.*, Xie, R.-G., Pu, L.*, Highly Enantioselective Synthesis of g-Hydroxy-a,b-acetylenic Esters by Asymmetric AlkyneAddition to Aldehydes, Angew. Chem. Int. Ed. 2006, 45, 122-125.

(16).   Zhao, Y.-C., Xiang, Y.-Z., Pu, L., Yang, M., Yu, X.-Q.*, Highly  b-Selective Epoxidation of the D5- and D4-Unsaturated Steroids Catalyzed by the Silica-Supported Polyhalogenated Ruthenium Porphyrin, Applied Catal. A: General, 2006, 301, 176-181.

(15).   Li, Q.-L., Huang, J., Wang, Q., Jiang, N., Xia, C.-Q., Lin, H.-H., Wu, J.,* Yu, X.-Q.*, Monometallic complexes of 1,4,7,10-tetraazacyclododecane containing an imidazolium side: Synthesis, characterization, and their interaction with plasmid DNA, Bioorg. Med. Chem., 2006, 14, 4151–4157.

(14).   Xia, C.-Q., Jiang, N., Zhang, J., Chen, S.-Y., Lin, H.-H.*, Tan, X.-Y., Yue, Y., Yu, X.-Q.*, The Conjugates of Uracil-Cyclen Zn (II) Complexes: Synthesis, Characterization and Their Interaction with Plasmid DNA, Bioorg. Med. Chem., 2006, 14, 5756-5764.

(13).   Wang, X.-Y., Zhang, J., Li, K., Jiang, N., Chen, S.-Y., Lin, H.-H.*, Huang, Y., Ma, L.-J., Yu, X.-Q.*, Synthesis and DNA cleavage activities of mononuclear macrocyclic polyamine zinc(II), copper(II), cobalt(II) complexes which linked with uracil, Bioorg. Med. Chem., 2006, 14, 6745-6751.

(12).    Jiang, F.-B., Huang, L.-Y., Meng, X.-G., Du, J., Yu, X.-Q.*, Zhao, Y.-F., Zeng, X.-C.*, Metallomicellar catalysis: Hydrolysis of phosphate monoester and phosphodiester by Cu(II), Zn(II) complexes of pyridyl ligands in CTAB micellar solution, J. Colloid Interface Sci., 2006, 303, 236-242.

(11).   Yue, Y., Zheng, Z.-G., Wu, B., Xia, C.-Q., Yu X.-Q.*, Copper-Catalyzed Cross-Coupling Reactions of Nucleobases with Arylboronic Acids: An Efficient Access to N-Arylnucleobases, Eur. J. Org. Chem., 2005, 5154–5157.

(10).   Peng, W., Liu, P.-Y., Jiang, N., Lin, H.-H., Zhang, G.-L., Liu, Y., Yu, X.-Q.*, Dinuclear macrocyclic polyamine zinc(II) complexes linked with Xexible spacers: Synthesis, characterization, and DNA cleavage, Bioorg. Chem., 2005, 33, 374–385.

(9).     Xiang, Q.-X.; Zhang, J.; Liu, P.-Y.; Xia, C.-Q.; Zhou, Z.-Y.; Xie, R.-G.; Yu, X.-Q.*, Dinuclear macrocyclic polyamine zinc (II) complexes: Syntheses, characterization and their interaction with plasmid DNA, J. Inorg. Biochem., 2005, 99(8), 1661-1669.

(8).     Jiang, F.-B.; Du J.; Yu, X.-Q.; Bao, J.-K.; Zeng, X.-C.*, Metallomicellar catalysis: accelerated hydrolysis of BNPP by copper(II), zinc(II), and nickel(II) complexes of long alkanol-imidazole in CTAB micellar solution, J. Colloid Interface Sci., 2004, 273, 497-504.

(7).     Lan, J.-B.; Chen, L.; Yu, X.-Q.*; You, J.-S.; Xie, R.-G.*, A simple copper salt catalysed the coupling of imidazole with arylboronic acids in protic solvent, Chem. Commun., 2004, 188-189.

(6).     Jiang, F.-B.; Jiang, B.-Y.; Yu, X.-Q.; Zeng, X.-C.*, Metallomicellar Catalysis. Effects of Bridge-Connecting Ligands on the Hydrolysis of PNPP Catalyzed by Zn(II), Co(II), and Ni(II) Complexes of Ethoxyl Diamine Ligands, Langmuir2002, 18(18), 6769~6774.

(5).     Liang, J.-L.; Huang, J.-S.; Yu, X.-Q.; Zhu, N.-Y. and Che, C.-M.*, Metalloporphyrin-Mediated Asymmetric Nitrogen-Atom Transfer to Hydrocarbons: Aziridination of Alkenes and Amidation of Saturated C-H Bonds Catalyzed by Chiral Ruthenium and Manganese Porphyrins, Chem. - Eur. J. , 2002, 8(7), 1563~1572.

(4).     Liang, J.-L.; Yu, X.-Q.; Che, C.-M.*, Amidation of silyl enol ethers and cholesteryl acetates with chiral ruthenium(II) Schiff base catalysts: catalytic and enantioselective studies, Chem. Commun., 2002, 124~125.

(3).     You, J.-S.; Yu, X.-Q.; Zhang, G.-L.; Xiang, Q.-X.; Lan, J.-B.; Xie, R.-G.*, Novel chiral imidazole cyclophane receptors: Synthesis and enantioselective recoginition for amino acid derivatives, Chem. Commun., 2001, 1816~1817.

(2).     Yu,X.-Q.; Huang, J.-S.; Yu, W.-Y.; Che, C.-M.*, Polymer-supported ruthenium porphyrins: Versatile and robust epoxidation catalysts with unusual selectivity, J. Am. Chem. Soc., 2000, 122, 5337~5342.

(1).     Yu, X.-Q.; Huang, J.-S.; Zhou, X.-G.; Che, C.-M.*, Amidation of saturated C-H bonds catalyzed by electron-deficient ruthenium and manganese porphyrins. A highly catalytic nitrogen atom transfer process, Org. Lett., 2000, 2, 2233~2236.